1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	T	G	I	V	E	E	R	G	E	V	T	G	R	E	A	L	V	D	A	A	R	L	T	I	R	G	P	M	V	T	A	D	A	G	H	G	D	S	I	A	V	N	G	V	C	L	T	V	V	D	V	L	P	D	G	Q	F	T
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	D	V	M	A	E	T	L	N	R	S	N	L	G	E	L	R	P	G	S	R	V	N	L	E	R	A	A	A	L	G	S	R	L	G	G	H	I	V	Q	G	H	V	D	A	T	G	E	I	V	A	R	C	P	S	E	H	W	E	V
Secondary structure
SS confidence
Disorder														?	?		?		?											?	?		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	R	I	E	M	P	A	S	V	A	R	Y	V	V	E	K	G	S	I	T	V	D	G	I	S	L	T	V	S	G	L	G	A	E	Q	R	D	W	F	E	V	S	L	I	P	T	T	R	E	L	T	T	L	G	S	A	A	V	G	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.
Sequence		R	V	N	L	E	V	D	V	V	A	K	Y	V	E	R	L	M	R	S	A	G
Secondary structure
SS confidence
Disorder																				?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 7%) Alpha helix ( 12%) Beta strand ( 53%)

Rank Aligned region

PDB 4e0f chain B Region: 1 - 200 Aligned: 197 Modelled: 200 Confidence: 100.0% Identity: 37% PDB header:transferase Chain: B: PDB Molecule:riboflavin synthase subunit alpha; PDBTitle: crystallographic structure of trimeric riboflavin synthase from2 brucella abortus in complex with riboflavin Phyre2 PDB 1kzl chain A Region: 1 - 200 Aligned: 196 Modelled: 200 Confidence: 100.0% Identity: 39% PDB header:transferase Chain: A: PDB Molecule:riboflavin synthase; PDBTitle: riboflavin synthase from s.pombe bound to2 carboxyethyllumazine Phyre2 PDB 1i8d chain B Region: 1 - 199 Aligned: 190 Modelled: 190 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: B: PDB Molecule:riboflavin synthase; PDBTitle: crystal structure of riboflavin synthase Phyre2 PDB 3a35 chain B Region: 1 - 186 Aligned: 181 Modelled: 186 Confidence: 100.0% Identity: 26% PDB header:luminescent protein Chain: B: PDB Molecule:lumazine protein; PDBTitle: crystal structure of lump complexed with riboflavin Phyre2 PDB 3ddy chain A Region: 1 - 186 Aligned: 172 Modelled: 186 Confidence: 100.0% Identity: 28% PDB header:luminescent protein Chain: A: PDB Molecule:lumazine protein; PDBTitle: structure of lumazine protein, an optical transponder of luminescent2 bacteria Phyre2 PDB 1kzl chain A domain 2 Region: 93 - 200 Aligned: 105 Modelled: 108 Confidence: 100.0% Identity: 36% Fold: Reductase/isomerase/elongation factor common domain Superfamily: Riboflavin synthase domain-like Family: Riboflavin synthase Phyre2 PDB 1i8d chain A domain 2 Region: 94 - 199 Aligned: 103 Modelled: 106 Confidence: 100.0% Identity: 37% Fold: Reductase/isomerase/elongation factor common domain Superfamily: Riboflavin synthase domain-like Family: Riboflavin synthase Phyre2 PDB 1i18 chain B Region: 1 - 97 Aligned: 96 Modelled: 97 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: B: PDB Molecule:riboflavin synthase alpha chain; PDBTitle: solution structure of the n-terminal domain of riboflavin synthase2 from e. coli Phyre2 PDB 1hze chain B Region: 1 - 97 Aligned: 96 Modelled: 97 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: B: PDB Molecule:riboflavin synthase alpha chain; PDBTitle: solution structure of the n-terminal domain of riboflavin synthase2 from e. coli Phyre2 PDB 1i8d chain A domain 1 Region: 1 - 93 Aligned: 92 Modelled: 93 Confidence: 100.0% Identity: 35% Fold: Reductase/isomerase/elongation factor common domain Superfamily: Riboflavin synthase domain-like Family: Riboflavin synthase Phyre2 PDB 1pkv chain A Region: 1 - 87 Aligned: 86 Modelled: 87 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: A: PDB Molecule:riboflavin synthase alpha chain; PDBTitle: the n-terminal domain of riboflavin synthase in complex with2 riboflavin Phyre2 PDB 1kzl chain A domain 1 Region: 1 - 92 Aligned: 91 Modelled: 92 Confidence: 100.0% Identity: 43% Fold: Reductase/isomerase/elongation factor common domain Superfamily: Riboflavin synthase domain-like Family: Riboflavin synthase Phyre2 PDB 1pkv chain B Region: 1 - 87 Aligned: 86 Modelled: 87 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: B: PDB Molecule:riboflavin synthase alpha chain; PDBTitle: the n-terminal domain of riboflavin synthase in complex with2 riboflavin Phyre2 PDB 5opj chain A Region: 104 - 188 Aligned: 66 Modelled: 84 Confidence: 79.9% Identity: 11% PDB header:oxidoreductase Chain: A: PDB Molecule:rhamnogalacturonan lyase; PDBTitle: rhamnogalacturonan lyase Phyre2 PDB 1a3x chain A domain 1 Region: 18 - 84 Aligned: 60 Modelled: 67 Confidence: 69.5% Identity: 25% Fold: PK beta-barrel domain-like Superfamily: PK beta-barrel domain-like Family: Pyruvate kinase beta-barrel domain Phyre2 PDB 1pkl chain A domain 1 Region: 17 - 84 Aligned: 61 Modelled: 68 Confidence: 69.1% Identity: 18% Fold: PK beta-barrel domain-like Superfamily: PK beta-barrel domain-like Family: Pyruvate kinase beta-barrel domain Phyre2 PDB 5mqo chain A Region: 104 - 188 Aligned: 66 Modelled: 85 Confidence: 66.4% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:non-reducing end beta-l-arabinofuranosidase; PDBTitle: glycoside hydrolase bt_1003 Phyre2 PDB 4qk0 chain C Region: 104 - 188 Aligned: 67 Modelled: 84 Confidence: 66.1% Identity: 18% PDB header:hydrolase Chain: C: PDB Molecule:gh127 beta-l-arabinofuranoside; PDBTitle: crystal structure of ara127n-se, a gh127 beta-l-arabinofuranosidase2 from geobacillus stearothermophilus t6 Phyre2 PDB 2g50 chain A domain 1 Region: 18 - 84 Aligned: 59 Modelled: 67 Confidence: 57.6% Identity: 29% Fold: PK beta-barrel domain-like Superfamily: PK beta-barrel domain-like Family: Pyruvate kinase beta-barrel domain Phyre2 PDB 6ex6 chain A Region: 104 - 188 Aligned: 69 Modelled: 85 Confidence: 53.2% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:six-hairpin glycosidase; PDBTitle: the gh127, beta-arabinofuranosidase, bt3674 Phyre2 1 c4e0fB_ 2 c1kzlA_ 3 c1i8dB_ 4 c3a35B_ 5 c3ddyA_ 6 d1kzla2 7 d1i8da2 8 c1i18B_ 9 c1hzeB_ 10 d1i8da1 11 c1pkvA_ 12 d1kzla1 13 c1pkvB_ 14 c5opjA_ 15 d1a3xa1 16 d1pkla1 17 c5mqoA_ 18 c4qk0C_ 19 d2g50a1 20 c6ex6A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99