1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	T	A	A	P	N	D	W	D	V	V	L	R	P	H	W	T	P	L	F	A	Y	A	A	A	F	L	I	A	V	A	H	V	A	G	G	L	L	L	K	V	G	S	S	G	V	V	F	Q	T	A	D	Q	V	A	M	G	A	L	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																				?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	V	L	A	G	A	V	L	L	F	A	R	P	R	L	R	V	G	S	A	G	L	S	V	R	N	L	L	G	D	R	I	V	G	W	S	E	V	I	G	V	S	F	P	G	G	S	R	W	A	R	I	D	L	A	D	D	E	Y	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.
Sequence		P	V	M	A	I	Q	A	V	D	K	D	R	A	V	A	A	M	D	T	V	R	S	L	L	A	R	Y	R	P	D	L	C	A	R
Secondary structure
SS confidence
Disorder										?	?																		?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 12%) Alpha helix ( 44%) Beta strand ( 24%) TM helix ( 11%) (View membrane topology prediction)

Rank Aligned region

PDB 1ef1 chain A domain 2 Region: 77 - 120 Aligned: 44 Modelled: 44 Confidence: 47.9% Identity: 20% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 1gg3 chain A domain 2 Region: 77 - 118 Aligned: 42 Modelled: 42 Confidence: 39.6% Identity: 26% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 1e5w chain A domain 2 Region: 77 - 120 Aligned: 44 Modelled: 44 Confidence: 38.4% Identity: 18% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 1j19 chain A domain 2 Region: 77 - 120 Aligned: 44 Modelled: 44 Confidence: 36.7% Identity: 18% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 1isn chain A domain 2 Region: 77 - 120 Aligned: 44 Modelled: 44 Confidence: 34.2% Identity: 14% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 1e5w chain A Region: 77 - 120 Aligned: 44 Modelled: 44 Confidence: 31.7% Identity: 18% PDB header:membrane protein Chain: A: PDB Molecule:moesin; PDBTitle: structure of isolated ferm domain and first long helix of moesin Phyre2 PDB 3bzk chain A domain 5 Region: 98 - 151 Aligned: 53 Modelled: 54 Confidence: 26.8% Identity: 15% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: Tex RuvX-like domain-like Phyre2 PDB 6adq chain P Region: 14 - 69 Aligned: 45 Modelled: 56 Confidence: 23.7% Identity: 18% PDB header:electron transport Chain: P: PDB Molecule:prokaryotic respiratory supercomplex associate factor 1 PDBTitle: respiratory complex ciii2civ2sod2 from mycobacterium smegmatis Phyre2 PDB 1iwg chain A domain 2 Region: 96 - 151 Aligned: 56 Modelled: 56 Confidence: 20.9% Identity: 20% Fold: Ferredoxin-like Superfamily: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Family: Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Phyre2 PDB 2kl4 chain A Region: 125 - 154 Aligned: 30 Modelled: 30 Confidence: 18.7% Identity: 17% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:bh2032 protein; PDBTitle: nmr structure of the protein nb7804a Phyre2 PDB 2i1j chain A Region: 77 - 107 Aligned: 31 Modelled: 31 Confidence: 17.1% Identity: 26% PDB header:cell adhesion, membrane protein Chain: A: PDB Molecule:moesin; PDBTitle: moesin from spodoptera frugiperda at 2.1 angstroms resolution Phyre2 PDB 1h4r chain A domain 2 Region: 77 - 148 Aligned: 69 Modelled: 72 Confidence: 15.9% Identity: 17% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 4gio chain A Region: 91 - 125 Aligned: 35 Modelled: 35 Confidence: 15.4% Identity: 9% PDB header:unknown function Chain: A: PDB Molecule:putative lipoprotein; PDBTitle: crystal structure of campylobacter jejuni cj0090 Phyre2 PDB 6ijj chain K Region: 45 - 69 Aligned: 25 Modelled: 25 Confidence: 12.2% Identity: 36% PDB header:membrane protein Chain: K: PDB Molecule:psak; PDBTitle: photosystem i of chlamydomonas reinhardtii Phyre2 PDB 6d2q chain A Region: 75 - 120 Aligned: 44 Modelled: 46 Confidence: 11.9% Identity: 27% PDB header:signaling protein Chain: A: PDB Molecule:ferm, rhogef (arhgef) and pleckstrin domain protein 1 PDBTitle: crystal structure of the ferm domain of zebrafish farp1 Phyre2 PDB 6igz chain K Region: 45 - 69 Aligned: 25 Modelled: 25 Confidence: 11.7% Identity: 24% PDB header:plant protein Chain: K: PDB Molecule:psak; PDBTitle: structure of psi-lhci Phyre2 PDB 2zpy chain A domain 2 Region: 77 - 148 Aligned: 69 Modelled: 72 Confidence: 11.6% Identity: 20% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 2i1k chain A Region: 77 - 106 Aligned: 30 Modelled: 30 Confidence: 10.8% Identity: 27% PDB header:cell adhesion, membrane protein Chain: A: PDB Molecule:moesin; PDBTitle: moesin from spodoptera frugiperda reveals the coiled-coil domain at2 3.0 angstrom resolution Phyre2 PDB 6odi chain H Region: 109 - 129 Aligned: 21 Modelled: 21 Confidence: 10.3% Identity: 24% PDB header:translocase Chain: H: PDB Molecule: PDBTitle: structure of cagy from a cryo-em reconstruction of a t4ss Phyre2 PDB 5n76 chain C Region: 81 - 129 Aligned: 49 Modelled: 49 Confidence: 9.8% Identity: 22% PDB header:nickel-binding protein Chain: C: PDB Molecule:coot; PDBTitle: crystal structure of the apo-form of the co dehydrogenase accessory2 protein coot from rhodospirillum rubrum Phyre2 1 d1ef1a2 2 d1gg3a2 3 d1e5wa2 4 d1j19a2 5 d1isna2 6 c1e5wA_ 7 d3bzka5 8 c6adqP_ 9 d1iwga2 10 c2kl4A_ 11 c2i1jA_ 12 d1h4ra2 13 c4gioA_ 14 c6ijjK_ 15 c6d2qA_ 16 c6igzK_ 17 d2zpya2 18 c2i1kA_ 19 c6odih_ 20 c5n76C_ 21 22 23 24 25 26 27 28 29 30