1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	L	A	L	Q	I	T	L	I	V	T	S	V	L	V	V	L	L	V	L	L	H	R	A	K	G	G	G	L	S	T	L	F	G	G	G	V	Q	S	S	L	S	G	S	T	V	V	E	K	N	L	D	R	L	T	L	F	V	T
Secondary structure
SS confidence
Disorder		?																																				?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.
Sequence		G	I	W	L	V	S	I	I	G	V	A	L	L	I	K	Y	R
Secondary structure
SS confidence
Disorder															?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 21%) Alpha helix ( 88%) Beta strand ( 0%) TM helix ( 47%) (View membrane topology prediction)

Rank Aligned region

PDB 2aki chain A Region: 1 - 77 Aligned: 77 Modelled: 77 Confidence: 98.2% Identity: 21% PDB header:protein transport Chain: A: PDB Molecule:protein-export membrane protein secg; PDBTitle: normal mode-based flexible fitted coordinates of a translocating2 secyeg protein-conducting channel into the cryo-em map of a secyeg-3 nascent chain-70s ribosome complex from e. coli Phyre2 PDB 3din chain E Region: 10 - 73 Aligned: 64 Modelled: 64 Confidence: 97.9% Identity: 22% PDB header:membrane protein, protein transport Chain: E: PDB Molecule:preprotein translocase subunit secg; PDBTitle: crystal structure of the protein-translocation complex formed by the2 secy channel and the seca atpase Phyre2 PDB 3dl8 chain F Region: 10 - 71 Aligned: 61 Modelled: 62 Confidence: 97.5% Identity: 28% PDB header:protein transport Chain: F: PDB Molecule:protein-export membrane protein secg; PDBTitle: structure of the complex of aquifex aeolicus secyeg and bacillus2 subtilis seca Phyre2 PDB 5aww chain G Region: 3 - 75 Aligned: 71 Modelled: 73 Confidence: 87.8% Identity: 20% PDB header:protein transport/immune system Chain: G: PDB Molecule:putative preprotein translocase, secg subunit; PDBTitle: precise resting state of thermus thermophilus secyeg Phyre2 PDB 5uz5 chain G Region: 50 - 56 Aligned: 7 Modelled: 7 Confidence: 11.7% Identity: 71% PDB header:nuclear protein/rna Chain: G: PDB Molecule:56 kda u1 small nuclear ribonucleoprotein component; PDBTitle: s. cerevisiae u1 snrnp Phyre2 PDB 2mxb chain A Region: 3 - 22 Aligned: 20 Modelled: 20 Confidence: 8.5% Identity: 40% PDB header:membrane protein Chain: A: PDB Molecule:erythropoietin receptor; PDBTitle: structure of the transmembrane domain of the mouse erythropoietin2 receptor Phyre2 PDB 1v54 chain L Region: 50 - 77 Aligned: 28 Modelled: 28 Confidence: 8.1% Identity: 14% Fold: Single transmembrane helix Superfamily: Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) Family: Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) Phyre2 PDB 3ipr chain C Region: 30 - 41 Aligned: 12 Modelled: 12 Confidence: 7.4% Identity: 8% PDB header:transferase Chain: C: PDB Molecule:pts system, iia component; PDBTitle: crystal structure of the enterococcus faecalis gluconate2 specific eiia phosphotransferase system component Phyre2 PDB 1pdo chain A Region: 30 - 40 Aligned: 11 Modelled: 11 Confidence: 7.1% Identity: 27% Fold: PTS system fructose IIA component-like Superfamily: PTS system fructose IIA component-like Family: EIIA-man component-like Phyre2 PDB 4tkz chain A Region: 30 - 40 Aligned: 11 Modelled: 11 Confidence: 6.9% Identity: 36% PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein gbs1890; PDBTitle: crystal structure of phosphotransferase system component eiia from2 streptococcus agalactiae Phyre2 PDB 3hl6 chain B Region: 22 - 38 Aligned: 17 Modelled: 17 Confidence: 6.9% Identity: 24% PDB header:unknown function Chain: B: PDB Molecule:pathogenicity island protein; PDBTitle: staphylococcus aureus pathogenicity island 3 orf9 protein Phyre2 PDB 2zvf chain G Region: 25 - 56 Aligned: 32 Modelled: 32 Confidence: 6.5% Identity: 25% PDB header:ligase Chain: G: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of archaeoglobus fulgidus alanyl-trna2 synthetase c-terminal dimerization domain Phyre2 PDB 6fmg chain C Region: 30 - 41 Aligned: 12 Modelled: 12 Confidence: 6.4% Identity: 25% PDB header:transferase Chain: C: PDB Molecule:pts system mannose-specific transporter subunit iiab; PDBTitle: structure of the mannose transporter iia domain from streptococcus2 pneumoniae Phyre2 PDB 2lp1 chain A Region: 5 - 26 Aligned: 22 Modelled: 22 Confidence: 6.3% Identity: 23% PDB header:membrane protein Chain: A: PDB Molecule:c99; PDBTitle: the solution nmr structure of the transmembrane c-terminal domain of2 the amyloid precursor protein (c99) Phyre2 PDB 1spf chain A Region: 51 - 74 Aligned: 24 Modelled: 24 Confidence: 6.1% Identity: 38% PDB header:lipoprotein(surface film) Chain: A: PDB Molecule:pulmonary surfactant-associated polypeptide c; PDBTitle: the nmr structure of the pulmonary surfactant-associated2 polypeptide sp-c in an apolar solvent contains a valyl-3 rich alpha-helix Phyre2 PDB 3lpz chain A Region: 30 - 41 Aligned: 12 Modelled: 12 Confidence: 6.0% Identity: 42% PDB header:protein transport Chain: A: PDB Molecule:get4 (yor164c homolog); PDBTitle: crystal structure of c. therm. get4 Phyre2 PDB 3lfh chain F Region: 30 - 41 Aligned: 12 Modelled: 12 Confidence: 6.0% Identity: 33% PDB header:transferase Chain: F: PDB Molecule:phosphotransferase system, mannose/fructose-specific PDBTitle: crystal structure of manxa from thermoanaerobacter tengcongensis Phyre2 PDB 5t3u chain A Region: 30 - 40 Aligned: 11 Modelled: 11 Confidence: 5.6% Identity: 36% PDB header:transport protein Chain: A: PDB Molecule:pts system, iia component; PDBTitle: crystal structure of the pts iia protein associated with the fucose2 utilization operon from streptococcus pneumoniae Phyre2 1 c2akiA_ 2 c3dinE_ 3 c3dl8F_ 4 c5awwG_ 5 c5uz5G_ 6 c2mxbA_ 7 d1v54l_ 8 c3iprC_ 9 d1pdoa_ 10 c4tkzA_ 11 c3hl6B_ 12 c2zvfG_ 13 c6fmgC_ 14 c2lp1A_ 15 c1spfA_ 16 c3lpzA_ 17 c3lfhF_ 18 c5t3uA_