1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	W	C	P	S	V	S	L	S	I	W	A	N	A	W	L	A	G	K	A	A	P	D	D	V	L	D	A	L	S	L	W	A	P	T	Q	S	V	A	A	Y	D	A	V	A	A	G	H	T	G	L	P	W	P	D	V	H	D	A	G
Secondary structure
SS confidence
Disorder		?	?	?	?																															?			?	?	?	?	?	?	?			?									?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	V	S	L	L	Q	T	L	R	A	A	V	G	R	R	R	L	R	G	T	I	N	V	V	L	P	V	P	G	D	V	R	G	L	A	A	G	T	Q	F	E	H	D	A	L	A	A	G	E	A	V	I	V	A	N	P	E	D	P	G
Secondary structure
SS confidence
Disorder		?	?	?								?	?	?	?	?	?																		?				?	?	?																		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	A	V	G	L	V	P	E	F	S	Y	G	D	V	D	E	A	A	Q	S	E	P	L	T	P	E	L	C	A	L	S	W	M	V	Y	S	L	P	G	A	P	V	L	E	H	Y	E	L	G	D	A	E	Y	A	L	R	S	A	V	R
Secondary structure
SS confidence
Disorder												?	?	?	?	?	?	?	?	?	?	?	?	?		?																?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	A	A	E	A	L	S	T	I	G	L	G	S	S	D	V	A	K	P	R	G	L	V	E	Q	L	L	E	S	S	R	Q	H	R	V	P	D	H	A	P	S	R	A	L	R	V	L	E	N	A	A	H	V	D	A	I	I	A	V	S
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?	?		?								?	?	?	?	?					?	?	?											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.
Sequence		A	G	L	S	R	L	P	I	G	T	Q	S	L	S	D	A	Q	R	A	T	D	A	L	R	P	L	T	A	V	V	R	S	A	R	M	S	A	V	T	A	I	L	H	S	A	W	P	D
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?										?	?	?																				?		?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 31%) Alpha helix ( 48%) Beta strand ( 7%)

Rank Aligned region

PDB 2n3x chain A Region: 273 - 287 Aligned: 15 Modelled: 15 Confidence: 30.1% Identity: 47% PDB header:dna binding protein Chain: A: PDB Molecule:tar dna-binding protein 43; PDBTitle: solution structure of tdp-43 amyloidogenic core region Phyre2 PDB 1wnk chain A Region: 268 - 280 Aligned: 13 Modelled: 13 Confidence: 24.8% Identity: 54% PDB header:transcription Chain: A: PDB Molecule:fibroin-modulator-binding-protein-1; PDBTitle: nmr structure of fmbp-1 tandem repeat 3 in 30%(v/v) tfe2 solution Phyre2 PDB 2n2c chain A Region: 273 - 287 Aligned: 15 Modelled: 15 Confidence: 19.4% Identity: 47% PDB header:dna binding protein Chain: A: PDB Molecule:tar dna-binding protein 43; PDBTitle: nmr structure of tdp-43 prion-like hydrophobic helix in dpc Phyre2 PDB 1vd9 chain A Region: 268 - 280 Aligned: 13 Modelled: 13 Confidence: 12.6% Identity: 54% PDB header:transcription Chain: A: PDB Molecule:fibroin-modulator-binding-protein-1; PDBTitle: solution structure of fmbp-1 tandem repeat 3 Phyre2 PDB 4gua chain B Region: 97 - 193 Aligned: 62 Modelled: 63 Confidence: 9.5% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:non-structural polyprotein; PDBTitle: alphavirus p23pro-zbd Phyre2 PDB 3v24 chain V Region: 3 - 18 Aligned: 16 Modelled: 16 Confidence: 8.5% Identity: 31% PDB header:ribosome Chain: V: PDB Molecule:ribosome modulation factor; PDBTitle: crystal structure of rmf bound to the 70s ribosome. this pdb entry2 contains coordinates for the 30s subunit with bound rmf of the 2nd3 ribosome in the asu Phyre2 PDB 2jrm chain A Region: 3 - 18 Aligned: 16 Modelled: 16 Confidence: 5.7% Identity: 25% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ribosome modulation factor; PDBTitle: solution nmr structure of ribosome modulation factor vp1593 from2 vibrio parahaemolyticus. northeast structural genomics target vpr55 Phyre2 1 c2n3xA_ 2 c1wnkA_ 3 c2n2cA_ 4 c1vd9A_ 5 c4guaB_ 6 c3v24V_ 7 c2jrmA_