1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	V	A	L	I	W	L	I	A	A	L	V	L	V	G	A	E	A	L	T	G	D	M	F	L	L	M	L	G	G	G	A	L	A	A	S	V	S	S	W	L	L	A	W	P	M	W	A	D	G	A	V	F	L	L	V	S	V	L
Secondary structure
SS confidence
Disorder		?	?																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	L	V	L	V	R	P	A	V	R	R	R	L	T	Q	T	K	G	V	Q	L	G	I	E	A	L	E	G	K	K	A	V	V	L	G	R	V	A	R	D	G	G	Q	V	K	L	D	G	Q	V	W	T	A	R	P	L	N	D	G	D
Secondary structure
SS confidence
Disorder																?	?	?	?	?	?	?	?	?	?																																?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.
Sequence		V	F	E	P	G	D	S	V	T	V	V	Q	I	D	G	A	T	A	V	V	F	K	D	V
Secondary structure
SS confidence
Disorder		?	?		?																		?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 17%) Alpha helix ( 49%) Beta strand ( 26%) TM helix ( 39%) (View membrane topology prediction)

Rank Aligned region

PDB 3cp0 chain A Region: 84 - 143 Aligned: 60 Modelled: 60 Confidence: 99.5% Identity: 43% PDB header:membrane protein Chain: A: PDB Molecule:membrane protein implicated in regulation of membrane PDBTitle: crystal structure of the soluble domain of membrane protein implicated2 in regulation of membrane protease activity from corynebacterium3 glutamicum Phyre2 PDB 2k5h chain A Region: 71 - 142 Aligned: 69 Modelled: 72 Confidence: 99.5% Identity: 35% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved protein; PDBTitle: solution nmr structure of protein encoded by mth693 from2 methanobacterium thermoautotrophicum: northeast structural3 genomics consortium target tt824a Phyre2 PDB 3wwv chain A Region: 80 - 143 Aligned: 62 Modelled: 64 Confidence: 99.4% Identity: 31% PDB header:unknown function Chain: A: PDB Molecule:stomatin operon partner protein; PDBTitle: c-terminal domain of stomatin operon partner protein 1510-c from2 pyrococcus horikoshii Phyre2 PDB 2exd chain A domain 1 Region: 71 - 142 Aligned: 68 Modelled: 72 Confidence: 99.4% Identity: 32% Fold: OB-fold Superfamily: NfeD domain-like Family: NfeD domain-like Phyre2 PDB 2k14 chain A Region: 82 - 143 Aligned: 61 Modelled: 62 Confidence: 99.0% Identity: 26% PDB header:unknown function Chain: A: PDB Molecule:yuaf protein; PDBTitle: solution structure of the soluble domain of the nfed2 protein yuaf from bacillus subtilis Phyre2 PDB 4xi7 chain A Region: 68 - 112 Aligned: 45 Modelled: 45 Confidence: 65.0% Identity: 16% PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase mib1; PDBTitle: crystal structure of the mzm-rep domains of mind bomb 1 in complex2 with jagged1 n-box peptide Phyre2 PDB 4tse chain A Region: 69 - 112 Aligned: 44 Modelled: 44 Confidence: 57.0% Identity: 16% PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase mib1; PDBTitle: crystal structure of the mib repeat domain of mind bomb 1 Phyre2 PDB 1tke chain A domain 1 Region: 104 - 131 Aligned: 23 Modelled: 28 Confidence: 53.1% Identity: 17% Fold: beta-Grasp (ubiquitin-like) Superfamily: TGS-like Family: TGS domain Phyre2 PDB 5z81 chain A Region: 101 - 130 Aligned: 25 Modelled: 30 Confidence: 35.0% Identity: 40% PDB header:chaperone Chain: A: PDB Molecule:heat shock protein 15; PDBTitle: trimeric structure of vibrio cholerae heat shock protein 15 at 2.32 angstrom resolution Phyre2 PDB 1dm9 chain A Region: 101 - 141 Aligned: 35 Modelled: 41 Confidence: 34.5% Identity: 29% Fold: Alpha-L RNA-binding motif Superfamily: Alpha-L RNA-binding motif Family: Heat shock protein 15 kD Phyre2 PDB 1dm9 chain A Region: 101 - 141 Aligned: 35 Modelled: 41 Confidence: 34.5% Identity: 29% PDB header:structural genomics Chain: A: PDB Molecule:hypothetical 15.5 kd protein in mrca-pcka intergenic PDBTitle: heat shock protein 15 kd Phyre2 PDB 1k25 chain A domain 2 Region: 103 - 131 Aligned: 29 Modelled: 29 Confidence: 33.3% Identity: 3% Fold: Penicillin-binding protein 2x (pbp-2x), c-terminal domain Superfamily: Penicillin-binding protein 2x (pbp-2x), c-terminal domain Family: Penicillin-binding protein 2x (pbp-2x), c-terminal domain Phyre2 PDB 1nyr chain A domain 2 Region: 104 - 131 Aligned: 23 Modelled: 28 Confidence: 32.1% Identity: 30% Fold: beta-Grasp (ubiquitin-like) Superfamily: TGS-like Family: TGS domain Phyre2 PDB 1ywk chain E Region: 76 - 135 Aligned: 58 Modelled: 60 Confidence: 31.7% Identity: 14% PDB header:isomerase Chain: E: PDB Molecule:4-deoxy-l-threo-5-hexosulose-uronate ketol- PDBTitle: crystal structure of 4-deoxy-1-threo-5-hexosulose-uronate2 ketol-isomerase from enterococcus faecalis Phyre2 PDB 3e0e chain A Region: 97 - 132 Aligned: 31 Modelled: 36 Confidence: 30.4% Identity: 23% PDB header:replication Chain: A: PDB Molecule:replication protein a; PDBTitle: crystal structure of a domain of replication protein a from2 methanococcus maripaludis. northeast structural genomics3 targe mrr110b Phyre2 PDB 1vio chain A domain 2 Region: 101 - 130 Aligned: 26 Modelled: 30 Confidence: 29.6% Identity: 15% Fold: Alpha-L RNA-binding motif Superfamily: Alpha-L RNA-binding motif Family: Pseudouridine synthase RsuA N-terminal domain Phyre2 PDB 6i52 chain B Region: 96 - 132 Aligned: 32 Modelled: 37 Confidence: 28.3% Identity: 25% PDB header:dna binding protein Chain: B: PDB Molecule:replication factor a protein 2; PDBTitle: yeast rpa bound to ssdna Phyre2 PDB 1v43 chain A domain 2 Region: 81 - 130 Aligned: 49 Modelled: 50 Confidence: 27.7% Identity: 24% Fold: OB-fold Superfamily: MOP-like Family: ABC-transporter additional domain Phyre2 PDB 1ywk chain A domain 1 Region: 76 - 135 Aligned: 58 Modelled: 60 Confidence: 26.1% Identity: 14% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: KduI-like Phyre2 PDB 1xru chain A domain 1 Region: 81 - 132 Aligned: 50 Modelled: 52 Confidence: 25.5% Identity: 18% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: KduI-like Phyre2 1 c3cp0A_ 2 c2k5hA_ 3 c3wwvA_ 4 d2exda1 5 c2k14A_ 6 c4xi7A_ 7 c4tseA_ 8 d1tkea1 9 c5z81A_ 10 d1dm9a_ 11 c1dm9A_ 12 d1k25a2 13 d1nyra2 14 c1ywkE_ 15 c3e0eA_ 16 d1vioa2 17 c6i52B_ 18 d1v43a2 19 d1ywka1 20 d1xrua1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99