1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	N	A	P	L	R	G	Q	V	Y	R	C	D	L	G	Y	G	A	K	P	W	L	I	V	S	N	N	A	R	N	R	H	T	A	D	V	V	A	V	R	L	T	T	T	R	R	T	I	P	T	W	V	A	M	G	P	S	D	P	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?																																																		?		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.
Sequence		T	G	Y	V	N	A	D	N	I	E	T	L	G	K	D	E	L	G	D	Y	L	G	E	V	T	P	A	T	M	N	K	I	N	T	A	L	A	T	A	L	G	L	P	W	P
Secondary structure
SS confidence
Disorder																																									?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 13%) Alpha helix ( 20%) Beta strand ( 39%)

Rank Aligned region

PDB 5xe3 chain B Region: 1 - 105 Aligned: 100 Modelled: 105 Confidence: 100.0% Identity: 97% PDB header:hydrolase/antitoxin Chain: B: PDB Molecule:endoribonuclease mazf4; PDBTitle: endoribonuclease in complex with its cognate antitoxin from2 mycobacterial species Phyre2 PDB 1ub4 chain A Region: 4 - 101 Aligned: 97 Modelled: 97 Confidence: 100.0% Identity: 22% Fold: SH3-like barrel Superfamily: Cell growth inhibitor/plasmid maintenance toxic component Family: Kid/PemK Phyre2 PDB 5wyg chain C Region: 1 - 103 Aligned: 102 Modelled: 102 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: C: PDB Molecule:probable endoribonuclease mazf7; PDBTitle: the crystal structure of the apo form of mtb mazf Phyre2 PDB 1m1f chain A Region: 5 - 100 Aligned: 96 Modelled: 96 Confidence: 100.0% Identity: 33% Fold: SH3-like barrel Superfamily: Cell growth inhibitor/plasmid maintenance toxic component Family: Kid/PemK Phyre2 PDB 1ne8 chain A Region: 3 - 103 Aligned: 101 Modelled: 101 Confidence: 100.0% Identity: 24% Fold: SH3-like barrel Superfamily: Cell growth inhibitor/plasmid maintenance toxic component Family: Kid/PemK Phyre2 PDB 4mzp chain C Region: 5 - 103 Aligned: 99 Modelled: 99 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: C: PDB Molecule:mazf mrna interferase; PDBTitle: mazf from s. aureus crystal form iii, c2221, 2.7 a Phyre2 PDB 5hk3 chain B Region: 5 - 102 Aligned: 95 Modelled: 98 Confidence: 99.9% Identity: 31% PDB header:hydrolase/dna Chain: B: PDB Molecule:endoribonuclease mazf6; PDBTitle: crystal structure of m. tuberculosis mazf-mt3 t52d-f62d mutant in2 complex with dna Phyre2 PDB 5hjz chain A Region: 5 - 102 Aligned: 98 Modelled: 98 Confidence: 99.9% Identity: 21% PDB header:hydrolase/rna Chain: A: PDB Molecule:endoribonuclease mazf9; PDBTitle: structure of m. tuberculosis mazf-mt1 (rv2801c) in complex with rna Phyre2 PDB 5cca chain A Region: 17 - 102 Aligned: 86 Modelled: 86 Confidence: 99.9% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:endoribonuclease mazf3; PDBTitle: crystal structure of mtb toxin Phyre2 PDB 3vub chain A Region: 8 - 100 Aligned: 88 Modelled: 93 Confidence: 95.9% Identity: 11% Fold: SH3-like barrel Superfamily: Cell growth inhibitor/plasmid maintenance toxic component Family: CcdB Phyre2 PDB 3jrz chain A Region: 17 - 100 Aligned: 79 Modelled: 84 Confidence: 95.9% Identity: 11% PDB header:toxin Chain: A: PDB Molecule:ccdb; PDBTitle: ccdbvfi-formii-ph5.6 Phyre2 PDB 5ikj chain A Region: 2 - 30 Aligned: 29 Modelled: 29 Confidence: 57.9% Identity: 28% PDB header:transcription Chain: A: PDB Molecule:cryptic loci regulator 2; PDBTitle: structure of clr2 bound to the clr1 c-terminus Phyre2 PDB 3llr chain A Region: 7 - 99 Aligned: 81 Modelled: 81 Confidence: 25.2% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:dna (cytosine-5)-methyltransferase 3a; PDBTitle: crystal structure of the pwwp domain of human dna (cytosine-5-)-2 methyltransferase 3 alpha Phyre2 PDB 1h3z chain A Region: 7 - 96 Aligned: 84 Modelled: 90 Confidence: 21.6% Identity: 12% Fold: SH3-like barrel Superfamily: Tudor/PWWP/MBT Family: PWWP domain Phyre2 PDB 2l89 chain A Region: 7 - 95 Aligned: 81 Modelled: 89 Confidence: 19.4% Identity: 16% PDB header:protein binding Chain: A: PDB Molecule:pwwp domain-containing protein 1; PDBTitle: solution structure of pdp1 pwwp domain reveals its unique binding2 sites for methylated h4k20 and dna Phyre2 PDB 4me8 chain A Region: 1 - 22 Aligned: 22 Modelled: 22 Confidence: 18.3% Identity: 9% PDB header:hydrolase Chain: A: PDB Molecule:signal peptidase i; PDBTitle: crystal structure of a signal peptidase i (ef3073) from enterococcus2 faecalis v583 at 2.27 a resolution Phyre2 PDB 2z3t chain D Region: 5 - 31 Aligned: 27 Modelled: 27 Confidence: 18.0% Identity: 19% PDB header:oxidoreductase Chain: D: PDB Molecule:cytochrome p450; PDBTitle: crystal structure of substrate free cytochrome p450 stap2 (cyp245a1) Phyre2 PDB 4rmo chain A Region: 17 - 102 Aligned: 84 Modelled: 85 Confidence: 9.8% Identity: 12% PDB header:toxin/rna Chain: A: PDB Molecule:cptn toxin; PDBTitle: crystal structure of the cptin type iii toxin-antitoxin system from2 eubacterium rectale Phyre2 PDB 4z5q chain A Region: 4 - 28 Aligned: 24 Modelled: 25 Confidence: 9.2% Identity: 29% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome p450 hydroxylase; PDBTitle: crystal structure of the lnmz cytochrome p450 hydroxylase from the2 leinamycin biosynthetic pathway of streptomyces atroolivaceus s-1403 at 1.8 a resolution Phyre2 PDB 2dkk chain A Region: 5 - 26 Aligned: 22 Modelled: 22 Confidence: 9.2% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome p450; PDBTitle: structure/function studies of cytochrome p450 158a1 from streptomyces2 coelicolor a3(2) Phyre2 1 c5xe3B_ 2 d1ub4a_ 3 c5wygC_ 4 d1m1fa_ 5 d1ne8a_ 6 c4mzpC_ 7 c5hk3B_ 8 c5hjzA_ 9 c5ccaA_ 10 d3vuba_ 11 c3jrzA_ 12 c5ikjA_ 13 c3llrA_ 14 d1h3za_ 15 c2l89A_ 16 c4me8A_ 17 c2z3tD_ 18 c4rmoA_ 19 c4z5qA_ 20 c2dkkA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36