1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	K	R	A	L	I	T	G	I	T	G	P	D	G	S	Y	L	A	K	L	P	L	K	G	Y	V	A	A	G	S	P	A	E	V	Y	F	C	W	A	T	R	N	Y	R	E	L	Y	G	L	L	A	V	N	S	I	W	F	N	H	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																?			?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	P	R	H	G	E	T	F	M	T	R	N	P	A	P	Y	R	G	R	Q	R	G	A	D	R	C	A	D	A	D	A	P	A	H	P	D	R	Y	Q	Y	W	G	V	P	A	S	V	R	G	V	I	D	R	A	M	G	V	C	V	E
Secondary structure
SS confidence
Disorder						?			?		?												?					?	?	?	?		?																								?	?	?	?	?
Disorder confidence
Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 22%) Alpha helix ( 68%) Beta strand ( 2%)

Rank Aligned region

PDB 3rfx chain B Region: 10 - 70 Aligned: 57 Modelled: 61 Confidence: 42.8% Identity: 11% PDB header:oxidoreductase Chain: B: PDB Molecule:uronate dehydrogenase; PDBTitle: crystal structure of uronate dehydrogenase from agrobacterium2 tumefaciens, y136a mutant complexed with nad Phyre2 PDB 1i24 chain A Region: 21 - 68 Aligned: 44 Modelled: 48 Confidence: 16.0% Identity: 14% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Tyrosine-dependent oxidoreductases Phyre2 PDB 1z7e chain C Region: 6 - 68 Aligned: 59 Modelled: 63 Confidence: 14.5% Identity: 17% PDB header:hydrolase Chain: C: PDB Molecule:protein arna; PDBTitle: crystal structure of full length arna Phyre2 PDB 1z45 chain A Region: 12 - 68 Aligned: 53 Modelled: 57 Confidence: 14.5% Identity: 9% PDB header:isomerase Chain: A: PDB Molecule:gal10 bifunctional protein; PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces cerevisiae3 complexed with nad, udp-glucose, and galactose Phyre2 PDB 6ckg chain A Region: 2 - 15 Aligned: 14 Modelled: 14 Confidence: 14.4% Identity: 43% PDB header:transferase Chain: A: PDB Molecule:d-glycerate 3-kinase; PDBTitle: d-glycerate 3-kinase from cryptococcus neoformans var. grubii serotype2 a (h99 / atcc 208821 / cbs 10515 / fgsc 9487) Phyre2 PDB 3ay3 chain C Region: 10 - 58 Aligned: 45 Modelled: 49 Confidence: 11.7% Identity: 11% PDB header:oxidoreductase Chain: C: PDB Molecule:nad-dependent epimerase/dehydratase; PDBTitle: crystal structure of glucuronic acid dehydrogeanse from2 chromohalobacter salexigens Phyre2 PDB 1n7g chain B Region: 2 - 20 Aligned: 19 Modelled: 19 Confidence: 11.1% Identity: 74% PDB header:lyase Chain: B: PDB Molecule:gdp-d-mannose-4,6-dehydratase; PDBTitle: crystal structure of the gdp-mannose 4,6-dehydratase2 ternary complex with nadph and gdp-rhamnose. Phyre2 PDB 1odf chain A Region: 2 - 15 Aligned: 14 Modelled: 14 Confidence: 9.2% Identity: 43% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Phosphoribulokinase/pantothenate kinase Phyre2 PDB 2z0l chain A Region: 53 - 61 Aligned: 9 Modelled: 9 Confidence: 8.7% Identity: 56% PDB header:replication Chain: A: PDB Molecule:early antigen protein d; PDBTitle: crystal structure of ebv-dna polymerase accessory protein2 bmrf1 Phyre2 PDB 6j9n chain B Region: 54 - 62 Aligned: 9 Modelled: 9 Confidence: 8.4% Identity: 56% PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:acriic3; PDBTitle: nmehnh+acriic3 Phyre2 PDB 6bwc chain A Region: 2 - 19 Aligned: 18 Modelled: 18 Confidence: 8.1% Identity: 39% PDB header:biosynthetic protein Chain: A: PDB Molecule:polysaccharide biosynthesis protein capd; PDBTitle: x-ray structure of pen from bacillus thuringiensis Phyre2 PDB 4lk3 chain A Region: 2 - 19 Aligned: 18 Modelled: 18 Confidence: 8.0% Identity: 56% PDB header:lyase Chain: A: PDB Molecule:udp-glucuronic acid decarboxylase 1; PDBTitle: crystal structure of human udp-xylose synthase r236a substitution Phyre2 PDB 1rpn chain A Region: 2 - 19 Aligned: 18 Modelled: 18 Confidence: 8.0% Identity: 72% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Tyrosine-dependent oxidoreductases Phyre2 PDB 2q1w chain C Region: 1 - 19 Aligned: 19 Modelled: 19 Confidence: 7.8% Identity: 47% PDB header:sugar binding protein Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase; PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+ Phyre2 PDB 3ha2 chain B Region: 100 - 115 Aligned: 16 Modelled: 15 Confidence: 7.6% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:nadph-quinone reductase; PDBTitle: crystal structure of protein (nadph-quinone reductase) from2 p.pentosaceus, northeast structural genomics consortium target ptr24a Phyre2 PDB 2cuq chain A domain 1 Region: 57 - 76 Aligned: 20 Modelled: 20 Confidence: 7.3% Identity: 30% Fold: Glucocorticoid receptor-like (DNA-binding domain) Superfamily: Glucocorticoid receptor-like (DNA-binding domain) Family: LIM domain Phyre2 PDB 5if3 chain B Region: 2 - 19 Aligned: 18 Modelled: 18 Confidence: 7.3% Identity: 44% PDB header:oxidoreductase Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr; PDBTitle: crystal structure of a short-chain dehydrogenase/reductase sdr from2 burkholderia vietnamiensis Phyre2 PDB 1n7h chain A Region: 2 - 19 Aligned: 18 Modelled: 18 Confidence: 7.2% Identity: 78% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Tyrosine-dependent oxidoreductases Phyre2 PDB 2qx7 chain A Region: 2 - 19 Aligned: 18 Modelled: 18 Confidence: 6.6% Identity: 39% PDB header:plant protein Chain: A: PDB Molecule:eugenol synthase 1; PDBTitle: structure of eugenol synthase from ocimum basilicum Phyre2 PDB 1jmt chain B Region: 99 - 104 Aligned: 6 Modelled: 6 Confidence: 6.6% Identity: 67% PDB header:rna binding protein Chain: B: PDB Molecule:splicing factor u2af 65 kda subunit; PDBTitle: x-ray structure of a core u2af65/u2af35 heterodimer Phyre2 1 c3rfxB_ 2 d1i24a_ 3 c1z7eC_ 4 c1z45A_ 5 c6ckgA_ 6 c3ay3C_ 7 c1n7gB_ 8 d1odfa_ 9 c2z0lA_ 10 c6j9nB_ 11 c6bwcA_ 12 c4lk3A_ 13 d1rpna_ 14 c2q1wC_ 15 c3ha2B_ 16 d2cuqa1 17 c5if3B_ 18 d1n7ha_ 19 c2qx7A_ 20 c1jmtB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43