1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	S	P	Q	L	C	P	K	V	S	I	V	S	T	T	H	N	Q	A	G	Y	A	R	Q	A	F	D	S	F	L	D	Q	Q	T	D	F	P	V	E	I	I	V	A	D	D	A	S	T	D	A	T	P	A	I	I	R	E	Y	A	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	Y	P	H	V	F	R	P	I	F	R	T	E	N	L	G	L	N	G	N	L	T	G	A	L	S	A	A	R	G	E	Y	V	A	L	C	E	A	D	D	Y	W	I	D	P	L	K	L	S	K	Q	V	A	F	L	D	R	H	P	K
Secondary structure
SS confidence
Disorder																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	T	V	C	F	H	P	V	R	V	I	W	E	D	G	H	A	K	D	S	K	F	P	P	V	R	V	R	G	N	L	S	L	D	A	L	I	L	M	N	F	I	Q	T	N	S	A	V	Y	R	R	L	E	R	Y	D	D	I	P	A
Secondary structure
SS confidence
Disorder																							?		?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	V	M	P	L	D	W	Y	L	H	V	R	H	A	V	H	G	D	I	A	M	L	P	D	T	M	A	V	Y	R	R	H	A	Q	G	M	W	H	N	Q	V	V	D	P	P	K	F	W	L	T	Q	G	P	G	H	A	A	T	F	D
Secondary structure
SS confidence
Disorder																																		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	M	L	D	L	F	P	G	D	P	A	R	E	E	L	I	A	V	M	A	D	W	I	L	R	Q	I	A	N	V	P	G	P	E	G	R	A	A	L	Q	E	T	I	A	R	H	P	R	I	A	M	L	A	L	Q	H	R	G	A	T
Secondary structure
SS confidence
Disorder											?																			?	?	?																									?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.
Sequence		P	A	R	R	L	K	T	Q	W	R	K	L	A	A	A	T	P	S	R	R	G	L	V	D	V	W	P	S	R	L	R	R	G	C	R	A
Secondary structure
SS confidence
Disorder		?	?											?	?	?	?	?	?	?	?	?			?										?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 12%) Alpha helix ( 50%) Beta strand ( 15%) TM helix ( 5%) (View membrane topology prediction)

Rank Aligned region

PDB 2z86 chain D Region: 3 - 227 Aligned: 219 Modelled: 225 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: D: PDB Molecule:chondroitin synthase; PDBTitle: crystal structure of chondroitin polymerase from escherichia coli2 strain k4 (k4cp) complexed with udp-glcua and udp Phyre2 PDB 1xhb chain A domain 2 Region: 3 - 212 Aligned: 207 Modelled: 210 Confidence: 100.0% Identity: 15% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain Phyre2 PDB 1xhb chain A Region: 3 - 210 Aligned: 204 Modelled: 208 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 1; PDBTitle: the crystal structure of udp-galnac: polypeptide alpha-n-2 acetylgalactosaminyltransferase-t1 Phyre2 PDB 6h4m chain A Region: 6 - 232 Aligned: 224 Modelled: 227 Confidence: 100.0% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:probable ss-1,3-n-acetylglucosaminyltransferase; PDBTitle: tarp-udp-glcnac-3rbop Phyre2 PDB 6e4r chain B Region: 2 - 221 Aligned: 215 Modelled: 220 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 9; PDBTitle: crystal structure of the drosophila melanogaster polypeptide n-2 acetylgalactosaminyl transferase pgant9b Phyre2 PDB 2d7i chain A Region: 3 - 236 Aligned: 229 Modelled: 234 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 10; PDBTitle: crystal structure of pp-galnac-t10 with udp, galnac and mn2+ Phyre2 PDB 5tz8 chain C Region: 8 - 214 Aligned: 204 Modelled: 207 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: C: PDB Molecule:glycosyl transferase; PDBTitle: crystal structure of s. aureus tars Phyre2 PDB 6iwq chain E Region: 3 - 245 Aligned: 239 Modelled: 243 Confidence: 100.0% Identity: 13% PDB header:transferase Chain: E: PDB Molecule:n-acetylgalactosaminyltransferase 7; PDBTitle: crystal structure of galnac-t7 with mn2+ Phyre2 PDB 2ffu chain A Region: 3 - 235 Aligned: 225 Modelled: 233 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 2; PDBTitle: crystal structure of human ppgalnact-2 complexed with udp and ea2 Phyre2 PDB 5nqa chain A Region: 3 - 210 Aligned: 204 Modelled: 208 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 4; PDBTitle: crystal structure of galnac-t4 in complex with the monoglycopeptide 3 Phyre2 PDB 4hg6 chain A Region: 1 - 238 Aligned: 231 Modelled: 235 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:cellulose synthase subunit a; PDBTitle: structure of a cellulose synthase - cellulose translocation2 intermediate Phyre2 PDB 5mm1 chain A Region: 8 - 261 Aligned: 243 Modelled: 254 Confidence: 100.0% Identity: 15% PDB header:membrane protein Chain: A: PDB Molecule:dolichol monophosphate mannose synthase; PDBTitle: dolichyl phosphate mannose synthase in complex with gdp and dolichyl2 phosphate mannose Phyre2 PDB 1qg8 chain A Region: 7 - 234 Aligned: 224 Modelled: 228 Confidence: 100.0% Identity: 20% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: Spore coat polysaccharide biosynthesis protein SpsA Phyre2 PDB 5hea chain A Region: 7 - 231 Aligned: 218 Modelled: 225 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:putative glycosyltransferase (galt1); PDBTitle: cgt structure in hexamer Phyre2 PDB 3f1y chain C Region: 7 - 238 Aligned: 227 Modelled: 232 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: C: PDB Molecule:mannosyl-3-phosphoglycerate synthase; PDBTitle: mannosyl-3-phosphoglycerate synthase from rubrobacter xylanophilus Phyre2 PDB 3ckv chain A Region: 7 - 234 Aligned: 222 Modelled: 228 Confidence: 100.0% Identity: 14% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of a mycobacterial protein Phyre2 PDB 3bcv chain A Region: 5 - 203 Aligned: 194 Modelled: 199 Confidence: 99.9% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:putative glycosyltransferase protein; PDBTitle: crystal structure of a putative glycosyltransferase from bacteroides2 fragilis Phyre2 PDB 4fix chain A Region: 2 - 264 Aligned: 256 Modelled: 260 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:udp-galactofuranosyl transferase glft2; PDBTitle: crystal structure of glft2 Phyre2 PDB 1omx chain B Region: 6 - 230 Aligned: 220 Modelled: 225 Confidence: 99.9% Identity: 9% PDB header:transferase Chain: B: PDB Molecule:alpha-1,4-n-acetylhexosaminyltransferase extl2; PDBTitle: crystal structure of mouse alpha-1,4-n-acetylhexosaminyltransferase2 (extl2) Phyre2 PDB 1omz chain A Region: 6 - 232 Aligned: 222 Modelled: 224 Confidence: 99.9% Identity: 9% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: Exostosin Phyre2 1 c2z86D_ 2 d1xhba2 3 c1xhbA_ 4 c6h4mA_ 5 c6e4rB_ 6 c2d7iA_ 7 c5tz8C_ 8 c6iwqE_ 9 c2ffuA_ 10 c5nqaA_ 11 c4hg6A_ 12 c5mm1A_ 13 d1qg8a_ 14 c5heaA_ 15 c3f1yC_ 16 c3ckvA_ 17 c3bcvA_ 18 c4fixA_ 19 c1omxB_ 20 d1omza_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161