1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	W	T	M	V	L	L	L	G	L	G	M	A	I	D	P	A	R	L	G	L	A	V	V	M	L	S	R	R	R	P	M	L	N	L	F	A	F	W	V	G	G	M	V	A	G	V	G	I	A	L	A	V	L	V	F	M	R	D	V
Secondary structure
SS confidence
Disorder		?	?																													?																											?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	L	A	A	I	Q	G	V	V	S	A	A	N	E	F	R	E	A	V	G	I	L	A	G	G	R	L	H	I	V	I	G	V	I	M	L	L	L	A	A	R	M	V	A	R	A	R	A	Q	V	G	V	P	V	G	P	V	G	V	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	G	G	M	S	A	L	A	L	A	Q	R	P	P	G	L	V	A	R	L	E	V	R	T	Q	Q	M	L	Q	G	D	V	V	W	P	A	F	V	V	G	V	A	S	S	A	P	P	F	E	S	V	V	A	L	T	V	I	M	A	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?		?	?		?	?	?	?	?	?																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	A	E	I	G	T	Q	L	G	A	F	V	V	F	T	L	L	V	L	A	V	I	E	I	P	L	V	A	Y	L	A	I	P	Q	Q	T	Q	Q	V	M	L	R	F	Q	D	W	V	R	S	N	R	R	Q	I	S	L	T	I	L	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.
Sequence		G	V	G	F	L	F	L	Y	Q	G	V	T	S	L
Secondary structure
SS confidence
Disorder											?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 31%) Alpha helix ( 71%) Beta strand ( 0%) TM helix ( 44%) (View membrane topology prediction)

Rank Aligned region

PDB 5vkv chain A Region: 6 - 254 Aligned: 192 Modelled: 198 Confidence: 96.4% Identity: 23% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c-type biogenesis protein ccda; PDBTitle: solution nmr structure of the membrane electron transporter ccda Phyre2 PDB 2o8p chain A domain 1 Region: 14 - 23 Aligned: 10 Modelled: 10 Confidence: 18.0% Identity: 30% Fold: alpha-alpha superhelix Superfamily: 14-3-3 protein Family: 14-3-3 protein Phyre2 PDB 1rc2 chain A Region: 13 - 59 Aligned: 46 Modelled: 47 Confidence: 17.8% Identity: 26% Fold: Aquaporin-like Superfamily: Aquaporin-like Family: Aquaporin-like Phyre2 PDB 5wlb chain F Region: 28 - 39 Aligned: 12 Modelled: 12 Confidence: 17.4% Identity: 50% PDB header:protein binding Chain: F: PDB Molecule:225-15 b; PDBTitle: kras g12v, bound to gppnhp and miniprotein 225-15a/b Phyre2 PDB 5wlb chain C Region: 28 - 39 Aligned: 12 Modelled: 12 Confidence: 15.6% Identity: 50% PDB header:protein binding Chain: C: PDB Molecule:225-15 b; PDBTitle: kras g12v, bound to gppnhp and miniprotein 225-15a/b Phyre2 PDB 6o4m chain A Region: 220 - 233 Aligned: 14 Modelled: 14 Confidence: 13.8% Identity: 21% PDB header:toxin Chain: A: PDB Molecule:melittin; PDBTitle: racemic melittin Phyre2 PDB 6o4m chain B Region: 220 - 233 Aligned: 14 Modelled: 14 Confidence: 13.8% Identity: 21% PDB header:toxin Chain: B: PDB Molecule:melittin; PDBTitle: racemic melittin Phyre2 PDB 6dst chain A Region: 220 - 233 Aligned: 14 Modelled: 14 Confidence: 13.8% Identity: 21% PDB header:toxin Chain: A: PDB Molecule:melittin; PDBTitle: recombinant melittin Phyre2 PDB 2mlt chain B Region: 220 - 233 Aligned: 14 Modelled: 14 Confidence: 13.8% Identity: 21% PDB header:toxin (hemolytic polypeptide) Chain: B: PDB Molecule:melittin; PDBTitle: melittin Phyre2 PDB 2mlt chain A Region: 220 - 233 Aligned: 14 Modelled: 14 Confidence: 13.8% Identity: 21% PDB header:toxin (hemolytic polypeptide) Chain: A: PDB Molecule:melittin; PDBTitle: melittin Phyre2 PDB 3efz chain A domain 1 Region: 13 - 23 Aligned: 11 Modelled: 11 Confidence: 13.0% Identity: 27% Fold: alpha-alpha superhelix Superfamily: 14-3-3 protein Family: 14-3-3 protein Phyre2 PDB 3efz chain A Region: 13 - 23 Aligned: 11 Modelled: 11 Confidence: 13.0% Identity: 27% PDB header:signaling protein Chain: A: PDB Molecule:14-3-3 protein; PDBTitle: crystal structure of a 14-3-3 protein from cryptosporidium parvum2 (cgd1_2980) Phyre2 PDB 6a9w chain A Region: 32 - 42 Aligned: 11 Modelled: 11 Confidence: 12.4% Identity: 45% PDB header:replication Chain: A: PDB Molecule:primase; PDBTitle: structure of the bifunctional dna primase-polymerase from phage nrs-1 Phyre2 PDB 2mw6 chain A Region: 222 - 233 Aligned: 12 Modelled: 12 Confidence: 12.2% Identity: 25% PDB header:toxin Chain: A: PDB Molecule:melittin; PDBTitle: structure of the bee venom toxin melittin with [(c5h5)ru]+ fragment2 attached to the tryptophan residue Phyre2 PDB 2npm chain B Region: 14 - 23 Aligned: 10 Modelled: 10 Confidence: 10.8% Identity: 60% PDB header:protein binding Chain: B: PDB Molecule:14-3-3 domain containing protein; PDBTitle: crystal structure of cryptosporidium parvum 14-3-3 protein in complex2 with peptide Phyre2 PDB 1bh1 chain A Region: 223 - 233 Aligned: 11 Modelled: 11 Confidence: 10.6% Identity: 27% PDB header:toxin Chain: A: PDB Molecule:melittin; PDBTitle: structural studies of d-pro melittin, nmr, 20 structures Phyre2 PDB 2n1p chain A Region: 232 - 247 Aligned: 16 Modelled: 16 Confidence: 10.3% Identity: 31% PDB header:viral protein Chain: A: PDB Molecule:non-structural protein 5b, ns5b; PDBTitle: structure of the c-terminal membrane domain of hcv ns5b protein Phyre2 PDB 1o9d chain A Region: 14 - 23 Aligned: 10 Modelled: 10 Confidence: 10.2% Identity: 60% Fold: alpha-alpha superhelix Superfamily: 14-3-3 protein Family: 14-3-3 protein Phyre2 PDB 3bvd chain C Region: 33 - 45 Aligned: 13 Modelled: 13 Confidence: 9.5% Identity: 31% PDB header:oxidoreductase Chain: C: PDB Molecule:cytochrome c oxidase polypeptide 2a; PDBTitle: structure of surface-engineered cytochrome ba3 oxidase from thermus2 thermophilus under xenon pressure, 100psi 5min Phyre2 PDB 1xme chain C domain 1 Region: 33 - 45 Aligned: 13 Modelled: 13 Confidence: 9.5% Identity: 31% Fold: Single transmembrane helix Superfamily: Bacterial ba3 type cytochrome c oxidase subunit IIa Family: Bacterial ba3 type cytochrome c oxidase subunit IIa Phyre2 1 c5vkvA_ 2 d2o8pa1 3 d1rc2a_ 4 c5wlbF_ 5 c5wlbC_ 6 c6o4mA_ 7 c6o4mB_ 8 c6dstA_ 9 c2mltB_ 10 c2mltA_ 11 d3efza1 12 c3efzA_ 13 c6a9wA_ 14 c2mw6A_ 15 c2npmB_ 16 c1bh1A_ 17 c2n1pA_ 18 d1o9da_ 19 c3bvdC_ 20 d1xmec1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37