Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD1522c_(mmpL12)_1714178_1717618
DateFri Aug 2 13:30:11 BST 2019
Unique Job ID38ba1a2b19b6e72a
SequenceVARHDEAKAG ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:64.926 Y:90.026 Z:94.018
Model (left) based on template c6ajjA_
Top template information
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
Confidence and coverage
Confidence:100.0% Coverage: 61%
704 residues ( 61% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
979 residues ( 85%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6ajjA_
100.0 19
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
2c5lq3F_
100.0 17
PDB header:transport protein
Chain: F: PDB Molecule:cmeb;
PDBTitle: structures and transport dynamics of the campylobacter jejuni2 multidrug efflux pump cmeb
3c3k07A_
100.0 13
PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa
4c4mt1A_
100.0 17
PDB header:membrane protein, tranport protein
Chain: A: PDB Molecule:drug efflux protein;
PDBTitle: crystal structure of the neisseria gonorrhoeae mtrd inner membrane2 multidrug efflux pump
5c6owsB_
100.0 14
PDB header:membrane protein
Chain: B: PDB Molecule:efflux pump membrane transporter;
PDBTitle: cryo-em structure of an acinetobacter baumannii multidrug efflux pump
6c2v50A_
100.0 15
PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein mexb;
PDBTitle: the missing part of the bacterial mexab-oprm system: structural2 determination of the multidrug exporter mexb
7c5khnB_
100.0 21
PDB header:membrane protein
Chain: B: PDB Molecule:rnd transporter;
PDBTitle: crystal structures of the burkholderia multivorans hopanoid2 transporter hpnn
8c4k0eA_
100.0 15
PDB header:transport protein
Chain: A: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
9c1oy8A_
100.0 15
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
10c6dmoA_
100.0 15
PDB header:protein binding
Chain: A: PDB Molecule:protein patched homolog 1;
PDBTitle: cryo-em structure of human ptch1 with three mutations2 l282q/t500f/p504l
11c6csxA_
100.0 17
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb;
PDBTitle: single particles cryo-em structure of acrb d407a associated with lipid2 bilayer at 3.0 angstrom
12c4k0eC_
100.0 14
PDB header:transport protein
Chain: C: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
13c3jd8A_
100.0 14
PDB header:membrane protein
Chain: A: PDB Molecule:niemann-pick c1 protein;
PDBTitle: cryo-em structure of the full-length human npc1 at 4.4 angstrom
14c3aqpB_
100.0 21
PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus
15c5xamA_
100.0 15
PDB header:membrane protein
Chain: A: PDB Molecule:protein translocase subunit secd;
PDBTitle: crystal structure of secdf in i form at 4 a resolution
16c5mg3D_
100.0 14
PDB header:chaperone
Chain: D: PDB Molecule:protein translocase subunit secd;
PDBTitle: em fitted model of bacterial holo-translocon
17d1iwga8
100.0 16
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
18c5mg3F_
100.0 12
PDB header:chaperone
Chain: F: PDB Molecule:protein translocase subunit secf;
PDBTitle: em fitted model of bacterial holo-translocon
19d1iwga7
99.9 18
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
20c5ensA_
99.0 10
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb,multidrug efflux pump
PDBTitle: rhodamine bound structure of bacterial efflux pump.
21c4r86B_
not modelled 98.5 10
PDB header:protein transport
Chain: B: PDB Molecule:rnd family aminoglycoside/multidrug efflux pump;
PDBTitle: crystal structure of aminoglycoside/multidrug efflux system acrd from2 salmonella typhimurium
22c2yvxD_
not modelled 87.0 13
PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte
23d1iwga2
not modelled 80.2 14
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
24d1iwga6
not modelled 75.1 16
Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
25d1iwga3
not modelled 53.3 9
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
26d1iwga4
not modelled 35.3 14
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
27c6hwhb_
not modelled 33.9 22
PDB header:electron transport
Chain: B: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit;
PDBTitle: structure of a functional obligate respiratory supercomplex from2 mycobacterium smegmatis
28c3j2wS_
not modelled 29.9 23
PDB header:virus
Chain: S: PDB Molecule:glycoprotein e2;
PDBTitle: electron cryo-microscopy of chikungunya virus
29c1ciiA_
not modelled 26.6 15
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
30c4fc2C_
not modelled 24.3 26
PDB header:hydrolase
Chain: C: PDB Molecule:poly(adp-ribose) glycohydrolase;
PDBTitle: crystal structure of mouse poly(adp-ribose) glycohydrolase (parg)2 catalytic domain
31c2vg2C_
not modelled 21.6 25
PDB header:transferase
Chain: C: PDB Molecule:undecaprenyl pyrophosphate synthetase;
PDBTitle: rv2361 with ipp
32c2mkaA_
not modelled 20.1 13
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
33c2mkaC_
not modelled 20.1 13
PDB header:immune system
Chain: C: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
34c2mkaB_
not modelled 20.1 13
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
35c2mk9A_
not modelled 20.1 13
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
36c2mk9B_
not modelled 20.1 13
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
37c3flhC_
not modelled 19.4 27
PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:uncharacterized protein lp_1913;
PDBTitle: crystal structure of lp_1913 protein from lactobacillus plantarum,2 northeast structural genomics consortium target lpr140b
38c2kseA_
not modelled 19.0 13
PDB header:transferase
Chain: A: PDB Molecule:sensor protein qsec;
PDBTitle: backbone structure of the membrane domain of e. coli histidine kinase2 receptor qsec, center for structures of membrane proteins (csmp)3 target 4311c
39c6o7ua_
not modelled 18.1 12
PDB header:membrane protein
Chain: A: PDB Molecule:
PDBTitle: saccharomyces cerevisiae v-atpase stv1-vo
40c5t6oA_
not modelled 15.6 39
PDB header:biosynthetic protein
Chain: A: PDB Molecule:poly-beta-hydroxybuterate polymerase;
PDBTitle: structure of the catalytic domain of the class i polyhydroxybutyrate2 synthase from cupriavidus necator
41d1mska_
not modelled 15.6 39
Fold:Methionine synthase activation domain-like
Superfamily:Methionine synthase activation domain-like
Family:Methionine synthase SAM-binding domain
42c1k98A_
not modelled 15.1 36
PDB header:transferase
Chain: A: PDB Molecule:methionine synthase;
PDBTitle: adomet complex of meth c-terminal fragment
43c6n52B_
not modelled 14.2 13
PDB header:membrane protein
Chain: B: PDB Molecule:metabotropic glutamate receptor 5;
PDBTitle: metabotropic glutamate receptor 5 apo form
44c2bbjB_
not modelled 14.2 8
PDB header:metal transport/membrane protein
Chain: B: PDB Molecule:divalent cation transport-related protein;
PDBTitle: crystal structure of the cora mg2+ transporter
45c2o2kA_
not modelled 13.9 42
PDB header:transferase
Chain: A: PDB Molecule:methionine synthase;
PDBTitle: crystal structure of the activation domain of human2 methionine synthase isoform/mutant d963e/k1071n
46c1p58F_
not modelled 13.7 29
PDB header:virus
Chain: F: PDB Molecule:envelope protein m;
PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction
47d1a87a_
not modelled 13.1 11
Fold:Toxins' membrane translocation domains
Superfamily:Colicin
Family:Colicin
48c1a87A_
not modelled 13.1 11
PDB header:bacteriocin
Chain: A: PDB Molecule:colicin n;
PDBTitle: colicin n
49c3rq9B_
not modelled 12.9 77
PDB header:tse2-binding protein
Chain: B: PDB Molecule:type vi secretion immunity protein;
PDBTitle: structure of tsi2, a tse2-immunity protein from pseudomonas aeruginosa
50c1p58E_
not modelled 12.9 27
PDB header:virus
Chain: E: PDB Molecule:envelope protein m;
PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction
51c3dntB_
not modelled 12.8 28
PDB header:transferase
Chain: B: PDB Molecule:protein hipa;
PDBTitle: structures of mdt proteins
52c5ietA_
not modelled 12.3 33
PDB header:gene regulation
Chain: A: PDB Molecule:bacterial proteasome activator;
PDBTitle: crystal structure of mycobacterium tuberculosis atp-independent2 proteasome activator
53c2q6mA_
not modelled 11.7 38
PDB header:toxin
Chain: A: PDB Molecule:cholix toxin;
PDBTitle: catalytic fragment of cholix toxin from vibrio cholerae in complex2 with the pj34 inhibitor
54c3sujA_
not modelled 11.6 24
PDB header:unknown function
Chain: A: PDB Molecule:cerato-platanin 1;
PDBTitle: crystal structure of cerato-platanin 1 from m. perniciosa (mpcp1)
55c5xavB_
not modelled 11.3 26
PDB header:biosynthetic protein
Chain: B: PDB Molecule:intracellular polyhydroxyalkanoate synthase;
PDBTitle: structure of phac from chromobacterium sp. usm2
56d2f20a1
not modelled 10.5 58
Fold:BB1717-like
Superfamily:BB1717-like
Family:BB1717-like
57c4b03A_
not modelled 10.5 10
PDB header:virus
Chain: A: PDB Molecule:dengue virus 1 e protein;
PDBTitle: 6a electron cryomicroscopy structure of immature dengue virus serotype2 1
58d1vlba2
not modelled 10.4 32
Fold:beta-Grasp (ubiquitin-like)
Superfamily:2Fe-2S ferredoxin-like
Family:2Fe-2S ferredoxin domains from multidomain proteins
59c5zlgA_
not modelled 10.3 10
PDB header:oxidoreductase
Chain: A: PDB Molecule:cytochrome b reductase 1;
PDBTitle: human duodenal cytochrome b (dcytb) in zinc ion and ascorbate bound2 form
60c5frtC_
not modelled 10.1 15
PDB header:oxidoreductase
Chain: C: PDB Molecule:dimeric (2fe-2s) protein;
PDBTitle: structure of the fesii (shethna) protein of azotobacter vinelandii
61c2k8oA_
not modelled 10.0 58
PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-l;
PDBTitle: solution structure of integrin alpha l
62c5sxpF_
not modelled 9.9 25
PDB header:signaling protein/ligase
Chain: F: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog;
PDBTitle: structural basis for the interaction between itch prr and beta-pix
63d1n62a2
not modelled 9.7 27
Fold:beta-Grasp (ubiquitin-like)
Superfamily:2Fe-2S ferredoxin-like
Family:2Fe-2S ferredoxin domains from multidomain proteins
64d2yvxa3
not modelled 9.4 13
Fold:MgtE membrane domain-like
Superfamily:MgtE membrane domain-like
Family:MgtE membrane domain-like
65c5knkB_
not modelled 9.4 19
PDB header:transferase
Chain: B: PDB Molecule:lipid a biosynthesis lauroyl acyltransferase;
PDBTitle: lipid a secondary acyltransferase lpxm from acinetobacter baumannii2 with catalytic residue substitution (e127a)
66c4gn0D_
not modelled 9.4 8
PDB header:signaling protein
Chain: D: PDB Molecule:hamp domain of af1503;
PDBTitle: de novo phasing of a hamp-complex using an improved arcimboldo method
67c1ffuA_
not modelled 9.3 39
PDB header:hydrolase
Chain: A: PDB Molecule:cuts, iron-sulfur protein of carbon monoxide
PDBTitle: carbon monoxide dehydrogenase from hydrogenophaga2 pseudoflava which lacks the mo-pyranopterin moiety of the3 molybdenum cofactor
68d1ffva2
not modelled 9.1 39
Fold:beta-Grasp (ubiquitin-like)
Superfamily:2Fe-2S ferredoxin-like
Family:2Fe-2S ferredoxin domains from multidomain proteins
69c4gf5S_
not modelled 9.0 30
PDB header:transferase
Chain: S: PDB Molecule:cals11;
PDBTitle: crystal structure of calicheamicin methyltransferase, cals11
70c3j2pD_
not modelled 8.9 27
PDB header:viral protein
Chain: D: PDB Molecule:small envelope protein m;
PDBTitle: cryoem structure of dengue virus envelope protein heterotetramer
71c5sxpG_
not modelled 8.9 25
PDB header:signaling protein/ligase
Chain: G: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog;
PDBTitle: structural basis for the interaction between itch prr and beta-pix
72c5u0pF_
not modelled 8.7 17
PDB header:transcription
Chain: F: PDB Molecule:mediator complex subunit 6;
PDBTitle: cryo-em structure of the transcriptional mediator
73d1dgja2
not modelled 8.7 32
Fold:beta-Grasp (ubiquitin-like)
Superfamily:2Fe-2S ferredoxin-like
Family:2Fe-2S ferredoxin domains from multidomain proteins
74c3tufA_
not modelled 8.6 9
PDB header:signaling protein
Chain: A: PDB Molecule:stage iii sporulation protein ah;
PDBTitle: structure of the spoiiq-spoiiiah pore forming complex.
75c6b2zf_
not modelled 8.5 14
PDB header:membrane protein
Chain: F: PDB Molecule:atp synthase subunit c, mitochondrial;
PDBTitle: cryo-em structure of the dimeric fo region of yeast mitochondrial atp2 synthase
76c6b8ht_
not modelled 8.4 14
PDB header:membrane protein
Chain: T: PDB Molecule:atp synthase subunit 9, mitochondrial;
PDBTitle: mosaic model of yeast mitochondrial atp synthase monomer
77c4fe1I_
not modelled 8.4 19
PDB header:photosynthesis
Chain: I: PDB Molecule:photosystem i reaction center subunit viii;
PDBTitle: improving the accuracy of macromolecular structure refinement at 7 a2 resolution
78d1jb0i_
not modelled 8.4 19
Fold:Single transmembrane helix
Superfamily:Subunit VIII of photosystem I reaction centre, PsaI
Family:Subunit VIII of photosystem I reaction centre, PsaI
79c2jpkA_
not modelled 8.3 29
PDB header:antimicrobial protein
Chain: A: PDB Molecule:bacteriocin lactococcin-g subunit beta;
PDBTitle: lactococcin g-b in dpc
80c6m97A_
not modelled 8.0 6
PDB header:transport protein
Chain: A: PDB Molecule:chimera protein of high affinity copper uptake protein 1
PDBTitle: crystal structure of the high-affinity copper transporter ctr1
81c6adqP_
not modelled 7.9 20
PDB header:electron transport
Chain: P: PDB Molecule:prokaryotic respiratory supercomplex associate factor 1
PDBTitle: respiratory complex ciii2civ2sod2 from mycobacterium smegmatis
82c4cbfB_
not modelled 7.9 17
PDB header:virus
Chain: B: PDB Molecule:m protein;
PDBTitle: near-atomic resolution cryo-em structure of dengue serotype 4 virus
83d2glia2
not modelled 7.8 56
Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:Classic zinc finger, C2H2
84c2jpmA_
not modelled 7.8 36
PDB header:antimicrobial protein
Chain: A: PDB Molecule:bacteriocin lactococcin-g subunit beta;
PDBTitle: lactococcin g-b in tfe
85d1iwga5
not modelled 7.7 9
Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
86d1rm6c2
not modelled 7.4 27
Fold:beta-Grasp (ubiquitin-like)
Superfamily:2Fe-2S ferredoxin-like
Family:2Fe-2S ferredoxin domains from multidomain proteins
87c6h4kA_
not modelled 7.3 43
PDB header:immune system
Chain: A: PDB Molecule:ubiquitin carboxyl-terminal hydrolase 25;
PDBTitle: structure of the usp25 c-terminal domain
88c2k1lA_
not modelled 7.3 21
PDB header:signaling protein
Chain: A: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 6.3
89c2k1lB_
not modelled 7.3 21
PDB header:signaling protein
Chain: B: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 6.3
90c2k1kB_
not modelled 7.3 21
PDB header:signaling protein
Chain: B: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 4.3
91c2k1kA_
not modelled 7.3 21
PDB header:signaling protein
Chain: A: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 4.3
92c5n9yB_
not modelled 7.1 14
PDB header:membrane protein
Chain: B: PDB Molecule:zinc transport protein zntb;
PDBTitle: the full-length structure of zntb
93c1wa7B_
not modelled 7.0 29
PDB header:sh3 domain
Chain: B: PDB Molecule:hypothetical 28.7 kda protein in dhfr 3'region
PDBTitle: sh3 domain of human lyn tyrosine kinase in complex with a2 herpesviral ligand
94c5xu1M_
not modelled 7.0 14
PDB header:transport protein
Chain: M: PDB Molecule:abc transporter permeae;
PDBTitle: structure of a non-canonical abc transporter from streptococcus2 pneumoniae r6
95c4p6vD_
not modelled 7.0 8
PDB header:oxidoreductase
Chain: D: PDB Molecule:na(+)-translocating nadh-quinone reductase subunit d;
PDBTitle: crystal structure of the na+-translocating nadh: ubiquinone2 oxidoreductase from vibrio cholerae
96c2xl1A_
not modelled 7.0 67
PDB header:translation
Chain: A: PDB Molecule:arginine attenuator peptide;
PDBTitle: structural basis of translational stalling by human cytomegalovirus2 (hcmv) and fungal arginine attenuator peptide (aap)
97c6nbxG_
not modelled 6.9 22
PDB header:oxidoreductase
Chain: G: PDB Molecule:nadh-quinone oxidoreductase subunit j;
PDBTitle: t.elongatus ndh (data-set 2)
98c1p58C_
not modelled 6.9 14
PDB header:virus
Chain: C: PDB Molecule:major envelope protein e;
PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction
99c6mu1C_
not modelled 6.9 11
PDB header:membrane protein
Chain: C: PDB Molecule:inositol 1,4,5-trisphosphate receptor type 1;
PDBTitle: structure of full-length ip3r1 channel bound with adenophostin a

Binding site prediction 

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Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below