1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	D	P	L	T	A	Q	E	Q	H	K	R	R	Q	A	V	R	E	L	M	P	R	T	P	F	I	G	G	L	G	I	V	F	E	R	Y	E	P	D	D	V	V	I	R	L	P	F	R	T	D	L	T	N	D	G	T	Y	F	H
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	G	V	I	A	S	V	M	D	T	A	G	A	A	A	A	W	S	N	H	D	F	D	R	G	T	R	A	A	T	V	A	M	S	I	Q	Y	T	G	A	A	K	R	C	D	L	L	C	H	A	R	T	A	R	R	R	K	E	L	T
Secondary structure
SS confidence
Disorder																								?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.
Sequence		F	T	E	I	T	A	T	D	P	D	G	N	I	V	A	H	A	V	Q	T	Y	R	I	V
Secondary structure
SS confidence
Disorder																									?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 11%) Alpha helix ( 25%) Beta strand ( 42%) TM helix ( 12%) (View membrane topology prediction)

Rank Aligned region

PDB 3e8p chain A Region: 2 - 143 Aligned: 139 Modelled: 140 Confidence: 100.0% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the protein q8e9m7 from shewanella oneidensis2 related to thioesterase superfamily. northeast structural genomics3 consortium target sor246. Phyre2 PDB 3hdu chain B Region: 11 - 144 Aligned: 134 Modelled: 134 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: B: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of a putative thioesterase (syn_01977) from2 syntrophus aciditrophicus sb at 2.50 a resolution Phyre2 PDB 3e1e chain E Region: 3 - 144 Aligned: 136 Modelled: 142 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: E: PDB Molecule:thioesterase family protein; PDBTitle: crystal structure of a thioesterase family protein from2 silicibacter pomeroyi. northeast structural genomics3 target sir180a Phyre2 PDB 1vh9 chain A Region: 19 - 144 Aligned: 124 Modelled: 124 Confidence: 100.0% Identity: 16% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 1sc0 chain A Region: 15 - 144 Aligned: 127 Modelled: 128 Confidence: 100.0% Identity: 13% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 1vh5 chain A Region: 19 - 144 Aligned: 124 Modelled: 124 Confidence: 100.0% Identity: 15% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 4qdb chain F Region: 15 - 144 Aligned: 128 Modelled: 130 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: F: PDB Molecule:thioesterase pa1618; PDBTitle: crystal structure of mutant thioesterase pa1618 (q49a) from2 pseudomonas aeruginosa Phyre2 PDB 3f1t chain B Region: 10 - 142 Aligned: 131 Modelled: 132 Confidence: 100.0% Identity: 22% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein q9i3c8_pseae; PDBTitle: crystal structure of the q9i3c8_pseae protein from pseudomonas2 aeruginosa. northeast structural genomics consortium target par319a. Phyre2 PDB 2fs2 chain A domain 1 Region: 10 - 142 Aligned: 128 Modelled: 128 Confidence: 100.0% Identity: 22% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 2qwz chain B Region: 14 - 144 Aligned: 129 Modelled: 131 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase (tm1040_1390) from2 silicibacter sp. tm1040 at 2.15 a resolution Phyre2 PDB 2pim chain A Region: 13 - 143 Aligned: 128 Modelled: 129 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase, phenylacetic acid2 degradation-related protein (reut_b4779) from ralstonia eutropha3 jmp134 at 2.20 a resolution Phyre2 PDB 3e29 chain C Region: 15 - 143 Aligned: 125 Modelled: 127 Confidence: 100.0% Identity: 25% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein q7we92_borbr; PDBTitle: x-ray structure of the protein q7we92_borbr from thioesterase2 superfamily. northeast structural genomics consortium target bor214a. Phyre2 PDB 3s4k chain A Region: 24 - 144 Aligned: 120 Modelled: 121 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:putative esterase rv1847/mt1895; PDBTitle: structure of a putative esterase rv1847/mt1895 from mycobacterium2 tuberculosis Phyre2 PDB 1q4u chain A Region: 25 - 144 Aligned: 119 Modelled: 120 Confidence: 100.0% Identity: 14% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 4rmm chain A Region: 10 - 144 Aligned: 127 Modelled: 135 Confidence: 100.0% Identity: 20% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of the q7nvp2_chrvo protein from chromobacterium2 violaceum. northeast structural genomics consortium target cvr191 Phyre2 PDB 2f0x chain A domain 1 Region: 10 - 143 Aligned: 131 Modelled: 134 Confidence: 100.0% Identity: 23% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 5hmc chain A Region: 24 - 144 Aligned: 119 Modelled: 121 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:azi13; PDBTitle: crystal structure of s. sahachiroi azig complexed with 5-methyl2 naphthoic acid Phyre2 PDB 4m20 chain D Region: 26 - 144 Aligned: 118 Modelled: 119 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: D: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of hypothetical protein sav0944 from staphylococcus2 aureus subsp. aureus mu50 Phyre2 PDB 1zki chain A domain 1 Region: 24 - 144 Aligned: 118 Modelled: 121 Confidence: 100.0% Identity: 22% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 3nwz chain D Region: 2 - 144 Aligned: 140 Modelled: 143 Confidence: 100.0% Identity: 19% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:bh2602 protein; PDBTitle: crystal structure of bh2602 protein from bacillus halodurans with coa,2 northeast structural genomics consortium target bhr199 Phyre2 1 c3e8pA_ 2 c3hduB_ 3 c3e1eE_ 4 d1vh9a_ 5 d1sc0a_ 6 d1vh5a_ 7 c4qdbF_ 8 c3f1tB_ 9 d2fs2a1 10 c2qwzB_ 11 c2pimA_ 12 c3e29C_ 13 c3s4kA_ 14 d1q4ua_ 15 c4rmmA_ 16 d2f0xa1 17 c5hmcA_ 18 c4m20D_ 19 d1zkia1 20 c3nwzD_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182