1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	T	A	R	E	V	G	R	I	G	L	R	K	L	L	Q	R	I	G	I	V	A	E	S	M	T	P	L	A	T	D	P	V	E	V	T	Q	L	L	D	A	R	W	Y	D	E	R	L	R	A	L	A	D	E	L	G	R	D	P	D
Secondary structure
SS confidence
Disorder		?	?																		?	?	?	?	?	?	?	?	?	?	?	?																								?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	V	R	A	E	A	A	G	Y	L	R	E	M	A	A	S	L	D	E	R	A	V	Q	A	W	R	G	F	S	R	W	L	M	R	A	Y	D	V	L	V	D	E	D	Q	I	T	Q	L	R	K	L	D	R	K	A	T	L	A	F	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	S	H	R	S	Y	L	D	G	M	L	L	P	E	A	I	L	A	N	R	L	S	P	A	L	T	F	G	G	A	N	L	N	F	F	P	M	G	A	W	A	K	R	T	G	A	I	F	I	R	R	Q	T	K	D	I	P	V	Y	R
Secondary structure
SS confidence
Disorder																																																								?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	V	L	R	A	Y	A	A	Q	L	V	Q	N	H	V	N	L	T	W	S	I	E	G	G	R	T	R	T	G	K	L	R	P	P	V	F	G	I	L	R	Y	I	T	D	A	V	D	E	I	D	G	P	E	V	Y	L	V	P	T	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		I	V	Y	D	Q	L	H	E	V	E	A	M	T	T	E	A	Y	G	A	V	K	R	P	E	D	L	R	F	L	V	R	L	A	R	Q	Q	G	E	R	L	G	R	A	Y	L	D	F	G	E	P	L	P	L	R	K	R	L	Q	E	M
Secondary structure
SS confidence
Disorder														?			?	?	?	?	?																?	?																				?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		R	A	D	K	S	G	T	G	S	E	I	E	R	I	A	L	D	V	E	H	R	I	N	R	A	T	P	V	T	P	T	A	V	V	S	L	A	L	L	G	A	D	R	S	L	S	I	S	E	V	L	A	T	V	R	P	L	A	S	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?																				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		I	A	A	R	N	W	A	V	A	G	A	A	D	L	T	N	R	S	T	I	R	W	T	L	H	Q	M	V	A	S	G	V	V	S	V	Y	D	A	G	T	E	A	V	W	G	I	G	E	D	Q	H	L	V	A	A	F	Y	R	N	T
Secondary structure
SS confidence
Disorder					?		?	?	?	?	?	?	?	?	?	?	?																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		A	I	H	I	L	V	D	R	A	V	A	E	L	A	L	L	A	A	A	E	T	T	T	N	G	S	V	S	P	A	T	V	R	D	E	A	L	S	L	R	D	L	L	K	F	E	F	L	F	S	G	R	A	Q	F	E	K	D	L	A
Secondary structure
SS confidence
Disorder																			?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		N	E	V	L	L	I	G	S	V	V	D	T	S	K	P	A	A	A	A	D	V	W	R	L	L	E	S	A	D	V	L	L	A	H	L	V	L	R	P	F	L	D	A	Y	H	I	V	A	D	R	L	A	A	H	E	D	D	S	F	D
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?		?	?																																		?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		E	E	G	F	L	A	E	C	L	Q	V	G	K	Q	W	E	L	Q	R	N	I	A	S	A	E	S	R	S	M	E	L	F	K	T	A	L	R	L	A	R	H	R	E	L	V	D	G	A	D	A	T	D	I	A	K	R	R	Q	Q	F
Secondary structure
SS confidence
Disorder																																																		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.
Sequence		A	D	E	I	A	T	A	T	R	R	V	N	T	I	A	E	L	A	R	R	Q
Secondary structure
SS confidence
Disorder																				?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 61%) Beta strand ( 7%) TM helix ( 14%) (View membrane topology prediction)

Rank Aligned region

PDB 5kym chain A Region: 79 - 324 Aligned: 195 Modelled: 223 Confidence: 99.6% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:1-acyl-sn-glycerol-3-phosphate acyltransferase; PDBTitle: crystal structure of the 1-acyl-sn-glycerophosphate (lpa)2 acyltransferase, plsc, from thermotoga maritima Phyre2 PDB 5f34 chain A Region: 59 - 245 Aligned: 175 Modelled: 187 Confidence: 96.3% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol mannoside acyltransferase; PDBTitle: crystal structure of membrane associated pata from mycobacterium2 smegmatis in complex with s-hexadecyl coenzyme a - p21 space group Phyre2 PDB 1iuq chain A Region: 42 - 321 Aligned: 247 Modelled: 253 Confidence: 91.5% Identity: 13% Fold: Glycerol-3-phosphate (1)-acyltransferase Superfamily: Glycerol-3-phosphate (1)-acyltransferase Family: Glycerol-3-phosphate (1)-acyltransferase Phyre2 PDB 5knk chain B Region: 59 - 209 Aligned: 141 Modelled: 151 Confidence: 85.7% Identity: 4% PDB header:transferase Chain: B: PDB Molecule:lipid a biosynthesis lauroyl acyltransferase; PDBTitle: lipid a secondary acyltransferase lpxm from acinetobacter baumannii2 with catalytic residue substitution (e127a) Phyre2 PDB 1t3l chain A domain 2 Region: 490 - 528 Aligned: 39 Modelled: 39 Confidence: 44.3% Identity: 18% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 6az1 chain X Region: 568 - 609 Aligned: 42 Modelled: 42 Confidence: 42.9% Identity: 19% PDB header:ribosome/antibiotic Chain: X: PDB Molecule:ribosomal protein s19e; PDBTitle: cryo-em structure of the small subunit of leishmania ribosome bound to2 paromomycin Phyre2 PDB 1m5w chain A Region: 99 - 238 Aligned: 82 Modelled: 105 Confidence: 41.6% Identity: 29% Fold: TIM beta/alpha-barrel Superfamily: Pyridoxine 5'-phosphate synthase Family: Pyridoxine 5'-phosphate synthase Phyre2 PDB 2jk1 chain A Region: 84 - 182 Aligned: 99 Modelled: 99 Confidence: 41.2% Identity: 10% PDB header:dna-binding Chain: A: PDB Molecule:hydrogenase transcriptional regulatory protein hupr1; PDBTitle: crystal structure of the wild-type hupr receiver domain Phyre2 PDB 3zey chain O Region: 568 - 608 Aligned: 41 Modelled: 41 Confidence: 40.1% Identity: 22% PDB header:ribosome Chain: O: PDB Molecule:ribosomal protein s19, putative; PDBTitle: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome Phyre2 PDB 5xyi chain T Region: 562 - 610 Aligned: 49 Modelled: 49 Confidence: 39.8% Identity: 16% PDB header:ribosome Chain: T: PDB Molecule:ribosomal protein s19e, putative; PDBTitle: small subunit of trichomonas vaginalis ribosome Phyre2 PDB 3iz6 chain S Region: 562 - 609 Aligned: 48 Modelled: 48 Confidence: 39.4% Identity: 13% PDB header:ribosome Chain: S: PDB Molecule:40s ribosomal protein s19 (s19e); PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome Phyre2 PDB 3j3a chain T Region: 568 - 610 Aligned: 43 Modelled: 43 Confidence: 39.1% Identity: 16% PDB header:ribosome Chain: T: PDB Molecule:40s ribosomal protein s19; PDBTitle: structure of the human 40s ribosomal proteins Phyre2 PDB 1vyv chain A domain 2 Region: 490 - 528 Aligned: 39 Modelled: 39 Confidence: 38.9% Identity: 18% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 1z67 chain A domain 1 Region: 45 - 79 Aligned: 35 Modelled: 35 Confidence: 37.3% Identity: 20% Fold: YidB-like Superfamily: YidB-like Family: YidB-like Phyre2 PDB 1vyu chain A domain 2 Region: 490 - 528 Aligned: 39 Modelled: 39 Confidence: 37.1% Identity: 15% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 2dpw chain A domain 1 Region: 202 - 237 Aligned: 36 Modelled: 36 Confidence: 32.4% Identity: 25% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: TTHA0179-like Phyre2 PDB 1wj5 chain A Region: 571 - 585 Aligned: 15 Modelled: 15 Confidence: 31.5% Identity: 47% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: An Obfc1 domain Phyre2 PDB 2v7f chain A domain 1 Region: 544 - 610 Aligned: 67 Modelled: 67 Confidence: 30.8% Identity: 18% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Rps19E-like Phyre2 PDB 3jyv chain T Region: 568 - 608 Aligned: 41 Modelled: 41 Confidence: 30.6% Identity: 22% PDB header:ribosome Chain: T: PDB Molecule:s19e protein; PDBTitle: structure of the 40s rrna and proteins and p/e trna for eukaryotic2 ribosome based on cryo-em map of thermomyces lanuginosus ribosome at3 8.9a resolution Phyre2 PDB 5xxu chain T Region: 562 - 613 Aligned: 52 Modelled: 52 Confidence: 29.4% Identity: 12% PDB header:ribosome Chain: T: PDB Molecule:ribosomal protein es19; PDBTitle: small subunit of toxoplasma gondii ribosome Phyre2 1 c5kymA_ 2 c5f34A_ 3 d1iuqa_ 4 c5knkB_ 5 d1t3la2 6 c6az1X_ 7 d1m5wa_ 8 c2jk1A_ 9 c3zeyO_ 10 c5xyiT_ 11 c3iz6S_ 12 c3j3aT_ 13 d1vyva2 14 d1z67a1 15 d1vyua2 16 d2dpwa1 17 d1wj5a_ 18 d2v7fa1 19 c3jyvT_ 20 c5xxuT_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99