1

.

.

.

.

.

.

.

.

10

.

.

.

.

.

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.

.

.

20

.

.

.

.

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.

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30

.

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.

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40

.

.

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.

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.

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.

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50

.

.

.

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.

.

.

.

60

Sequence

M

T

A

G

A

G

G

S

P

P

T

R

R

C

P

A

T

E

D

R

A

P

A

T

V

A

T

P

S

S

A

D

P

T

A

S

R

A

V

S

W

W

S

V

H

E

H

V

A

P

V

L

D

A

A

G

S

W

P

M

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

70

.

.

.

.

.

.

.

.

.

80

.

.

.

.

.

.

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.

90

.

.

.

.

.

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.

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.

100

.

.

.

.

.

.

.

.

.

110

.

.

.

.

.

.

.

.

.

120

Sequence

A

G

T

P

A

W

R

Q

L

D

D

A

D

P

R

K

W

A

A

I

C

D

A

A

R

H

W

A

L

R

V

E

T

C

Q

E

A

M

A

Q

A

S

R

D

V

S

A

A

A

D

W

P

G

I

A

R

E

I

V

R

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

130

.

.

Sequence

R

R

G

V

Y

I

P

R

A

G

V

A

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 40%) Alpha helix ( 51%) Beta strand ( 5%)

Rank Aligned region

PDB 2g7r chain A Region: 58 - 70 Aligned: 13 Modelled: 13 Confidence: 19.3% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:mucosa-associated lymphoid tissue lymphoma translocation PDBTitle: x-ray structure of the death domain of the human mucosa associated2 lymphoid tissue lymphoma translocation protein 1 Phyre2 PDB 2m8g chain X Region: 95 - 122 Aligned: 28 Modelled: 28 Confidence: 13.8% Identity: 25% PDB header:transcription Chain: X: PDB Molecule:transcriptional regulator; PDBTitle: structure, function, and tethering of dna-binding domains in 542 transcriptional activators Phyre2 PDB 3gw6 chain F Region: 46 - 104 Aligned: 47 Modelled: 59 Confidence: 12.8% Identity: 21% PDB header:chaperone Chain: F: PDB Molecule:endo-n-acetylneuraminidase; PDBTitle: intramolecular chaperone Phyre2 PDB 1eto chain B Region: 95 - 122 Aligned: 28 Modelled: 28 Confidence: 12.2% Identity: 25% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 4l5e chain A Region: 95 - 122 Aligned: 28 Modelled: 28 Confidence: 11.2% Identity: 14% PDB header:protein binding Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of a. aeolicus ntrc1 dna binding domain Phyre2 PDB 2eqf chain A Region: 5 - 18 Aligned: 14 Modelled: 14 Confidence: 10.8% Identity: 43% PDB header:hydrolase Chain: A: PDB Molecule:tumor necrosis factor, alpha-induced protein 3; PDBTitle: solution structure of the 7th a20-type zinc finger domain2 from human tumor necrosis factor, alpha-induced protein3 Phyre2 PDB 2jp6 chain A Region: 93 - 101 Aligned: 9 Modelled: 9 Confidence: 10.6% Identity: 67% PDB header:toxin Chain: A: PDB Molecule:potassium channel toxin alpha-ktx 18.1; PDBTitle: structural and functional characterization of the2 recombinant form of the kv1.3 channel blocker tc32 Phyre2 PDB 2lgz chain A Region: 32 - 43 Aligned: 12 Modelled: 12 Confidence: 9.8% Identity: 25% PDB header:transferase, membrane protein Chain: A: PDB Molecule:dolichyl-diphosphooligosaccharide--protein PDBTitle: solution structure of stt3p Phyre2 PDB 4hik chain A Region: 38 - 58 Aligned: 21 Modelled: 21 Confidence: 9.7% Identity: 14% PDB header:dna binding protein Chain: A: PDB Molecule:protection of telomeres protein 1; PDBTitle: crystal structure of schizosaccharomyces pombe pot1pc bound to ssdna2 (ggttacggt) Phyre2 PDB 3vza chain F Region: 65 - 78 Aligned: 14 Modelled: 14 Confidence: 9.5% Identity: 50% PDB header:cell cycle Chain: F: PDB Molecule:centromere protein t; PDBTitle: crystal structure of the chicken spc24-spc25 globular domain in2 complex with cenp-t peptide Phyre2 PDB 3vza chain E Region: 65 - 78 Aligned: 14 Modelled: 14 Confidence: 9.5% Identity: 50% PDB header:cell cycle Chain: E: PDB Molecule:centromere protein t; PDBTitle: crystal structure of the chicken spc24-spc25 globular domain in2 complex with cenp-t peptide Phyre2 PDB 3ush chain B Region: 81 - 98 Aligned: 18 Modelled: 17 Confidence: 8.6% Identity: 22% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the q2s0r5 protein from salinibacter ruber,2 northeast structural genomics consortium target srr207 Phyre2 PDB 4ioh chain A Region: 81 - 98 Aligned: 18 Modelled: 18 Confidence: 8.5% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tll1086 protein; PDBTitle: crystal structure of the tll1086 protein from thermosynechococcus2 elongatus, northeast structural genomics consortium target ter258 Phyre2 PDB 1fip chain A Region: 95 - 122 Aligned: 28 Modelled: 28 Confidence: 7.3% Identity: 25% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1ntc chain A Region: 95 - 122 Aligned: 28 Modelled: 28 Confidence: 7.3% Identity: 14% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1umq chain A Region: 95 - 122 Aligned: 28 Modelled: 28 Confidence: 7.0% Identity: 25% PDB header:dna-binding protein Chain: A: PDB Molecule:photosynthetic apparatus regulatory protein; PDBTitle: solution structure and dna binding of the effector domain2 from the global regulator prra(rega) from r. sphaeroides:3 insights into dna binding specificity Phyre2 PDB 1umq chain A Region: 95 - 122 Aligned: 28 Modelled: 28 Confidence: 7.0% Identity: 25% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1pu6 chain A Region: 36 - 80 Aligned: 44 Modelled: 45 Confidence: 6.3% Identity: 11% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: 3-Methyladenine DNA glycosylase III (MagIII) Phyre2 PDB 1vaj chain A domain 1 Region: 38 - 56 Aligned: 19 Modelled: 19 Confidence: 6.1% Identity: 37% Fold: AMMECR1-like Superfamily: AMMECR1-like Family: AMMECR1-like Phyre2 PDB 4noo chain A Region: 65 - 83 Aligned: 19 Modelled: 19 Confidence: 5.8% Identity: 11% PDB header:immune system Chain: A: PDB Molecule:vgrg protein; PDBTitle: molecular mechanism for self-protection against type vi secretion2 system in vibrio cholerae Phyre2 1 c2g7rA_ 2 c2m8gX_ 3 c3gw6F_ 4 d1etob_ 5 c4l5eA_ 6 c2eqfA_ 7 c2jp6A_ 8 c2lgzA_ 9 c4hikA_ 10 c3vzaF_ 11 c3vzaE_ 12 c3ushB_ 13 c4iohA_ 14 d1fipa_ 15 d1ntca_ 16 c1umqA_ 17 d1umqa_ 18 d1pu6a_ 19 d1vaja1 20 c4nooA_ 21