1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	T	G	D	T	V	A	D	F	E	L	P	D	Q	T	G	T	P	R	R	L	S	V	L	L	S	D	G	P	V	V	L	F	F	Y	P	A	A	M	T	P	G	C	T	K	E	A	C	H	F	R	D	L	A	K	E	F	A	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	R	A	S	R	V	G	I	S	T	D	P	V	R	K	Q	A	K	F	A	E	V	R	R	F	D	Y	P	L	L	S	D	A	Q	G	T	V	A	A	Q	F	G	V	K	R	G	L	L	G	K	L	M	P	V	K	R	T	T	F	V
Secondary structure
SS confidence
Disorder																								?																										?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.
Sequence		I	D	T	D	R	K	V	L	D	V	I	S	S	E	F	S	M	D	A	H	A	D	K	A	L	A	T	L	R	A	I	R	S	G
Secondary structure
SS confidence
Disorder																	?																	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 8%) Alpha helix ( 32%) Beta strand ( 23%)

Rank Aligned region

PDB 5epf chain A Region: 1 - 153 Aligned: 153 Modelled: 153 Confidence: 100.0% Identity: 100% PDB header:oxidoreductase Chain: A: PDB Molecule:peroxiredoxin; PDBTitle: crystal structure of peroxidoxin bcpb from mycobacterium tuberculosis Phyre2 PDB 1prx chain A Region: 1 - 152 Aligned: 150 Modelled: 152 Confidence: 100.0% Identity: 25% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Glutathione peroxidase-like Phyre2 PDB 2v2g chain C Region: 1 - 152 Aligned: 151 Modelled: 152 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: C: PDB Molecule:peroxiredoxin 6; PDBTitle: crystal structure of the c45s mutant of the peroxiredoxin 62 of arenicola marina. monoclinic form Phyre2 PDB 5ykj chain A Region: 1 - 152 Aligned: 150 Modelled: 152 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:peroxiredoxin prx1, mitochondrial; PDBTitle: structural basis of the thiol resolving mechanism in yeast2 mitochondrial 1-cys peroxiredoxin via glutathione/thioredoxin systems Phyre2 PDB 1xcc chain A Region: 1 - 152 Aligned: 152 Modelled: 152 Confidence: 100.0% Identity: 16% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Glutathione peroxidase-like Phyre2 PDB 6feu chain J Region: 1 - 152 Aligned: 149 Modelled: 152 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: J: PDB Molecule:peroxiredoxin; PDBTitle: prxq2, a 1-cys peroxiredoxin of the thermo-acidophilic archaeon2 sulfolobus islandicus Phyre2 PDB 3drn chain B Region: 1 - 153 Aligned: 148 Modelled: 148 Confidence: 100.0% Identity: 31% PDB header:oxidoreductase Chain: B: PDB Molecule:peroxiredoxin, bacterioferritin comigratory protein PDBTitle: the crystal structure of bcp1 from sulfolobus sulfataricus Phyre2 PDB 5ovq chain L Region: 2 - 152 Aligned: 148 Modelled: 151 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: L: PDB Molecule:peroxiredoxin; PDBTitle: crystal structure of the peroxiredoxin (ahpc2) from the2 hyperthermophilic bacteria aquifex aeolicus vf Phyre2 PDB 5zte chain A Region: 2 - 152 Aligned: 148 Modelled: 151 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: A: PDB Molecule:2-cys peroxiredoxin bas1, chloroplastic; PDBTitle: crystal structure of prxa c119s mutant from arabidopsis thaliana Phyre2 PDB 2i81 chain B Region: 3 - 152 Aligned: 146 Modelled: 150 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: B: PDB Molecule:2-cys peroxiredoxin; PDBTitle: crystal structure of plasmodium vivax 2-cys peroxiredoxin,2 reduced Phyre2 PDB 2h66 chain G Region: 1 - 152 Aligned: 148 Modelled: 152 Confidence: 100.0% Identity: 20% PDB header:structural genomics/oxidoreductase Chain: G: PDB Molecule:pv-pf14_0368; PDBTitle: the crystal structure of plasmodium vivax 2-cys2 peroxiredoxin Phyre2 PDB 1uul chain A Region: 1 - 152 Aligned: 148 Modelled: 152 Confidence: 100.0% Identity: 24% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Glutathione peroxidase-like Phyre2 PDB 3tkp chain B Region: 1 - 152 Aligned: 148 Modelled: 149 Confidence: 100.0% Identity: 23% PDB header:oxidoreductase Chain: B: PDB Molecule:peroxiredoxin-4; PDBTitle: crystal structure of full-length human peroxiredoxin 4 in the reduced2 form Phyre2 PDB 3sbc chain G Region: 1 - 152 Aligned: 148 Modelled: 152 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: G: PDB Molecule:peroxiredoxin tsa1; PDBTitle: crystal structure of saccharomyces cerevisiae tsa1c47s mutant protein Phyre2 PDB 1zof chain B Region: 1 - 152 Aligned: 148 Modelled: 152 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: B: PDB Molecule:alkyl hydroperoxide-reductase; PDBTitle: crystal structure of alkyl hydroperoxide-reductase (ahpc)2 from helicobacter pylori Phyre2 PDB 3w6g chain P Region: 1 - 152 Aligned: 148 Modelled: 152 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: P: PDB Molecule:probable peroxiredoxin; PDBTitle: structure of peroxiredoxin from anaerobic hyperthermophilic archaeon2 pyrococcus horikoshii Phyre2 PDB 3tue chain B Region: 1 - 152 Aligned: 148 Modelled: 152 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: B: PDB Molecule:tryparedoxin peroxidase; PDBTitle: the structure of tryparedoxin peroxidase i from leishmania major Phyre2 PDB 1qmv chain A Region: 1 - 152 Aligned: 147 Modelled: 152 Confidence: 100.0% Identity: 24% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Glutathione peroxidase-like Phyre2 PDB 3keb chain B Region: 1 - 153 Aligned: 152 Modelled: 153 Confidence: 100.0% Identity: 12% PDB header:oxidoreductase Chain: B: PDB Molecule:probable thiol peroxidase; PDBTitle: thiol peroxidase from chromobacterium violaceum Phyre2 PDB 2c0d chain A Region: 3 - 152 Aligned: 146 Modelled: 146 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin peroxidase 2; PDBTitle: structure of the mitochondrial 2-cys peroxiredoxin from2 plasmodium falciparum Phyre2 1 c5epfA_ 2 d1prxa_ 3 c2v2gC_ 4 c5ykjA_ 5 d1xcca_ 6 c6feuJ_ 7 c3drnB_ 8 c5ovqL_ 9 c5zteA_ 10 c2i81B_ 11 c2h66G_ 12 d1uula_ 13 c3tkpB_ 14 c3sbcG_ 15 c1zofB_ 16 c3w6gP_ 17 c3tueB_ 18 d1qmva_ 19 c3kebB_ 20 c2c0dA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356