1

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10

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20

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30

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40

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50

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60

Sequence

M

P

K

A

K

T

H

S

G

A

S

K

R

F

R

R

T

G

T

G

K

I

V

R

Q

K

A

N

R

R

H

L

L

E

H

K

P

S

T

R

T

R

R

L

D

G

R

T

V

V

A

A

N

D

T

K

R

V

T

S

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

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Sequence

L

L

N

G

Secondary structure

SS confidence

Disorder

?

?

?

Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 53%) Alpha helix ( 28%) Beta strand ( 22%)

Rank Aligned region

PDB 5o60 chain E Region: 2 - 64 Aligned: 63 Modelled: 63 Confidence: 100.0% Identity: 84% PDB header:ribosome Chain: E: PDB Molecule:50s ribosomal protein l4; PDBTitle: structure of the 50s large ribosomal subunit from mycobacterium2 smegmatis Phyre2 PDB 2qam chain 3 domain 1 Region: 2 - 63 Aligned: 62 Modelled: 62 Confidence: 100.0% Identity: 40% Fold: L35p-like Superfamily: L35p-like Family: Ribosomal protein L35p Phyre2 PDB 2j01 chain 8 domain 1 Region: 2 - 63 Aligned: 62 Modelled: 62 Confidence: 100.0% Identity: 39% Fold: L35p-like Superfamily: L35p-like Family: Ribosomal protein L35p Phyre2 PDB 3bbo chain 5 Region: 3 - 63 Aligned: 61 Modelled: 61 Confidence: 100.0% Identity: 44% PDB header:ribosome Chain: 5: PDB Molecule:ribosomal protein l35; PDBTitle: homology model for the spinach chloroplast 50s subunit fitted to 9.4a2 cryo-em map of the 70s chlororibosome Phyre2 PDB 2zjr chain 3 domain 1 Region: 2 - 63 Aligned: 62 Modelled: 62 Confidence: 100.0% Identity: 34% Fold: L35p-like Superfamily: L35p-like Family: Ribosomal protein L35p Phyre2 PDB 4wfb chain 3 Region: 2 - 61 Aligned: 60 Modelled: 60 Confidence: 100.0% Identity: 42% PDB header:ribosome Chain: 3: PDB Molecule:50s ribosomal protein l35; PDBTitle: the crystal structure of the large ribosomal subunit of staphylococcus2 aureus in complex with bc-3205 Phyre2 PDB 1vw4 chain Z Region: 4 - 63 Aligned: 59 Modelled: 60 Confidence: 99.6% Identity: 34% PDB header:ribosome Chain: Z: PDB Molecule:mitochondrial ribosomal protein ynl122c; PDBTitle: structure of the yeast mitochondrial large ribosomal subunit Phyre2 PDB 4v19 chain 8 Region: 3 - 62 Aligned: 60 Modelled: 60 Confidence: 97.6% Identity: 28% PDB header:ribosome Chain: 8: PDB Molecule:mitoribosomal protein bl35m, mrpl35; PDBTitle: structure of the large subunit of the mammalian mitoribosome, part 12 of 2 Phyre2 PDB 4ce4 chain 8 Region: 3 - 61 Aligned: 59 Modelled: 59 Confidence: 97.3% Identity: 29% PDB header:ribosome Chain: 8: PDB Molecule:mrpl35; PDBTitle: 39s large subunit of the porcine mitochondrial ribosome Phyre2 PDB 4byl chain 5 Region: 14 - 26 Aligned: 13 Modelled: 13 Confidence: 9.1% Identity: 15% PDB header:ribosome Chain: 5: PDB Molecule:ubiquitin-40s ribosomal protein s31; PDBTitle: cryo-em reconstruction of the 80s-eif5b-met-itrnamet2 eukaryotic translation initiation complex Phyre2 PDB 3u5c chain F Region: 14 - 26 Aligned: 13 Modelled: 13 Confidence: 9.1% Identity: 15% PDB header:ribosome Chain: F: PDB Molecule:40s ribosomal protein s5; PDBTitle: the structure of the eukaryotic ribosome at 3.0 a resolution. this2 entry contains proteins of the 40s subunit, ribosome a Phyre2 PDB 4byt chain 5 Region: 14 - 26 Aligned: 13 Modelled: 13 Confidence: 9.1% Identity: 15% PDB header:ribosome Chain: 5: PDB Molecule:ubiquitin-40s ribosomal protein s31; PDBTitle: cryo-em reconstruction of the 80s-eif5b-met-itrnamet2 eukaryotic translation initiation complex Phyre2 PDB 4uer chain 9 Region: 14 - 26 Aligned: 13 Modelled: 13 Confidence: 9.1% Identity: 15% PDB header:translation Chain: 9: PDB Molecule:es31; PDBTitle: 40s-eif1-eif1a-eif3-eif3j translation initiation complex from2 lachancea kluyveri Phyre2 PDB 2m7e chain A Region: 11 - 19 Aligned: 9 Modelled: 9 Confidence: 8.0% Identity: 44% PDB header:calmodulin-binding protein Chain: A: PDB Molecule:calcium-transporting atpase 2, plasma membrane-type; PDBTitle: solution structure of the calmodulin-binding domain of plant calcium-2 atpase aca2 Phyre2 PDB 5xxu chain F Region: 14 - 26 Aligned: 13 Modelled: 13 Confidence: 7.8% Identity: 23% PDB header:ribosome Chain: F: PDB Molecule:ribosomal protein us7; PDBTitle: small subunit of toxoplasma gondii ribosome Phyre2 PDB 2xzm chain 9 Region: 5 - 26 Aligned: 22 Modelled: 22 Confidence: 6.5% Identity: 27% PDB header:ribosome Chain: 9: PDB Molecule:rps31e; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1 Phyre2 PDB 2xzn chain 9 Region: 5 - 26 Aligned: 22 Modelled: 22 Confidence: 6.5% Identity: 27% PDB header:ribosome Chain: 9: PDB Molecule:rps31e; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 2 Phyre2 PDB 2l53 chain B Region: 25 - 33 Aligned: 9 Modelled: 9 Confidence: 6.3% Identity: 78% PDB header:ca-binding protein/proton transport Chain: B: PDB Molecule:voltage-gated sodium channel type v alpha isoform b PDBTitle: solution nmr structure of apo-calmodulin in complex with the iq motif2 of human cardiac sodium channel nav1.5 Phyre2 PDB 3j38 chain F Region: 5 - 26 Aligned: 22 Modelled: 22 Confidence: 5.6% Identity: 27% PDB header:ribosome Chain: F: PDB Molecule:40s ribosomal protein s5a; PDBTitle: structure of the d. melanogaster 40s ribosomal proteins Phyre2 1 c5o60e_ 2 d2qam31 3 d2j0181 4 c3bbo5_ 5 d2zjr31 6 c4wfb3_ 7 c1vw4Z_ 8 c4v198_ 9 c4ce48_ 10 c4byl5_ 11 c3u5cf_ 12 c4byt5_ 13 c4uer9_ 14 c2m7eA_ 15 c5xxuf_ 16 c2xzm9_ 17 c2xzn9_ 18 c2l53B_ 19 c3j38f_