Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD1647_(-)_1856781_1857731
DateFri Aug 2 13:30:24 BST 2019
Unique Job IDa7f3dd48b77b74e7
SequenceLAGSARTTYP ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:48.071 Y:48.830 Z:45.656
Model (left) based on template c6fhtB_
Top template information
PDB header:lyase
Chain: B: PDB Molecule:bacteriophytochrome,adenylate cyclase;
PDBTitle: crystal structure of an artificial phytochrome regulated2 adenylate/guanylate cyclase in its dark adapted pr form
Confidence and coverage
Confidence:100.0% Coverage: 60%
191 residues ( 60% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
245 residues ( 78%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

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Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6fhtB_



100.0 27
PDB header:lyase
Chain: B: PDB Molecule:bacteriophytochrome,adenylate cyclase;
PDBTitle: crystal structure of an artificial phytochrome regulated2 adenylate/guanylate cyclase in its dark adapted pr form
2c1y10C_



100.0 25
PDB header:lyase
Chain: C: PDB Molecule:hypothetical protein rv1264/mt1302;
PDBTitle: mycobacterial adenylyl cyclase rv1264, holoenzyme, inhibited state
3c4yusA_



100.0 19
PDB header:lyase
Chain: A: PDB Molecule:family 3 adenylate cyclase;
PDBTitle: crystal structure of photoactivated adenylyl cyclase of a2 cyanobacteriaoscillatoria acuminata in hexagonal form
4c5nbyA_



100.0 18
PDB header:lyase
Chain: A: PDB Molecule:beta subunit of photoactivated adenylyl cyclase;
PDBTitle: structure of a bacterial light-regulated adenylyl cylcase
5c6r4oA_



100.0 23
PDB header:membrane protein
Chain: A: PDB Molecule:adenylate cyclase 9;
PDBTitle: structure of a truncated adenylyl cyclase bound to mant-gtp, forskolin2 and an activated stimulatory galphas protein
6d1fx2a_



100.0 24
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
7d1fx4a_



100.0 26
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
8c6r4pA_



100.0 26
PDB header:membrane protein
Chain: A: PDB Molecule:adenylate cyclase 9;
PDBTitle: structure of a soluble domain of adenylyl cyclase bound to an2 activated stimulatory g protein
9c3mr7B_



100.0 24
PDB header:hydrolase
Chain: B: PDB Molecule:adenylate/guanylate cyclase/hydrolase, alpha/beta fold
PDBTitle: crystal structure of adenylate/guanylate cyclase/hydrolase from2 silicibacter pomeroyi
10c1wc6B_



100.0 30
PDB header:lyase
Chain: B: PDB Molecule:adenylate cyclase;
PDBTitle: soluble adenylyl cyclase cyac from s. platensis in complex2 with rp-atpalphas in presence of bicarbonate
11c4cllA_



100.0 19
PDB header:lyase
Chain: A: PDB Molecule:adenylate cyclase type 10;
PDBTitle: crystal structure of human soluble adenylyl cyclase in complex with2 bicarbonate
12c3uvjC_



100.0 21
PDB header:lyase
Chain: C: PDB Molecule:guanylate cyclase soluble subunit alpha-3;
PDBTitle: crystal structure of the catalytic domain of the heterodimeric human2 soluble guanylate cyclase 1.
13c4wp3E_



100.0 31
PDB header:lyase
Chain: E: PDB Molecule:ma1120;
PDBTitle: crystal structure of adenylyl cyclase from mycobacterium avium ma11202 wild type
14d1wc1a_



100.0 29
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
15c5o5kC_



100.0 20
PDB header:membrane protein
Chain: C: PDB Molecule:adenylate cyclase;
PDBTitle: x-ray structure of a bacterial adenylyl cyclase soluble domain
16c1cjkA_



100.0 20
PDB header:lyase/lyase/signaling protein
Chain: A: PDB Molecule:adenylate cyclase, type v;
PDBTitle: complex of gs-alpha with the catalytic domains of mammalian adenylyl2 cyclase: complex with adenosine 5'-(alpha thio)-triphosphate (rp),3 mg, and mn
17c1ybuA_



100.0 29
PDB header:hydrolase
Chain: A: PDB Molecule:lipj;
PDBTitle: mycobacterium tuberculosis adenylyl cyclase rv1900c chd, in complex2 with a substrate analog.
18d1azsa_



100.0 20
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
19c2w01C_



100.0 26
PDB header:lyase
Chain: C: PDB Molecule:adenylate cyclase;
PDBTitle: crystal structure of the guanylyl cyclase cya2
20c3r5gB_



100.0 26
PDB header:lyase
Chain: B: PDB Molecule:cyab;
PDBTitle: crystal structure of the adenylyl cyclase cyab from p. aeruginosa
21c2wz1B_



not modelled 100.0 21
PDB header:lyase
Chain: B: PDB Molecule:guanylate cyclase soluble subunit beta-1;
PDBTitle: structure of the catalytic domain of human soluble guanylate cyclase 12 beta 3.
22d1azsb_



not modelled 100.0 19
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
23c3et6A_



not modelled 100.0 22
PDB header:lyase
Chain: A: PDB Molecule:soluble guanylyl cyclase beta;
PDBTitle: the crystal structure of the catalytic domain of a eukaryotic2 guanylate cyclase
24c1yk9A_



not modelled 100.0 22
PDB header:lyase
Chain: A: PDB Molecule:adenylate cyclase;
PDBTitle: crystal structure of a mutant form of the mycobacterial2 adenylyl cyclase rv1625c
25c6aoaA_



not modelled 100.0 26
PDB header:lyase
Chain: A: PDB Molecule:bacterio-rhodopsin/guanylyl cyclase 1 fusion protein;
PDBTitle: monomeric crystal structure of the e497/c566d double mutant of the2 guanylyl cyclase domain of the rhogc fusion protein from the aquatic3 fungus blastocladiella emersonii
26c1w25B_



not modelled 97.8 14
PDB header:signaling protein
Chain: B: PDB Molecule:stalked-cell differentiation controlling protein;
PDBTitle: response regulator pled in complex with c-digmp
27c4zmuD_



not modelled 97.5 13
PDB header:lyase
Chain: D: PDB Molecule:diguanylate cyclase;
PDBTitle: dcsbis, a diguanylate cyclase from pseudomonas aeruginosa
28c5llxB_



not modelled 97.2 13
PDB header:transferase
Chain: B: PDB Molecule:diguanylate cyclase (ggdef) domain-containing protein;
PDBTitle: bacteriophytochrome activated diguanylyl cyclase from idiomarina2 species a28l with gtp bound
29c3ezuA_



not modelled 97.1 18
PDB header:signaling protein
Chain: A: PDB Molecule:ggdef domain protein;
PDBTitle: crystal structure of multidomain protein of unknown function with2 ggdef-domain (np_951600.1) from geobacter sulfurreducens at 1.95 a3 resolution
30c3breA_



not modelled 97.1 24
PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: crystal structure of p.aeruginosa pa3702
31c3i5aA_



not modelled 97.0 20
PDB header:signaling protein
Chain: A: PDB Molecule:response regulator/ggdef domain protein;
PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae
32c6d9mA_



not modelled 97.0 13
PDB header:hydrolase
Chain: A: PDB Molecule:fusion protein of endolysin,response receiver sensor
PDBTitle: t4-lysozyme fusion to geobacter ggdef
33c2qv6D_



not modelled 97.0 17
PDB header:hydrolase
Chain: D: PDB Molecule:gtp cyclohydrolase iii;
PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions
34c3i5cA_



not modelled 96.7 19
PDB header:signaling protein
Chain: A: PDB Molecule:fusion of general control protein gcn4 and wspr response
PDBTitle: crystal structure of a fusion protein containing the leucine zipper of2 gcn4 and the ggdef domain of wspr from pseudomonas aeruginosa
35c3ignA_



not modelled 96.6 13
PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase;
PDBTitle: crystal structure of the ggdef domain from marinobacter aquaeolei2 diguanylate cyclase complexed with c-di-gmp - northeast structural3 genomics consortium target mqr89a
36c3mtkA_



not modelled 96.2 12
PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase/phosphodiesterase;
PDBTitle: x-ray structure of diguanylate cyclase/phosphodiesterase from2 caldicellulosiruptor saccharolyticus, northeast structural genomics3 consortium target clr27c
37c4wxoA_



not modelled 96.1 15
PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: sadc (300-487) from pseudomonas aeruginosa pao1
38c3hvwA_



not modelled 95.7 12
PDB header:lyase
Chain: A: PDB Molecule:diguanylate-cyclase (dgc);
PDBTitle: crystal structure of the ggdef domain of the pa2567 protein from2 pseudomonas aeruginosa, northeast structural genomics consortium3 target par365c
39c5euhA_



not modelled 95.2 16
PDB header:membrane protein
Chain: A: PDB Molecule:putative ggdef domain membrane protein;
PDBTitle: crystal structure of the c-di-gmp-bound ggdef domain of p. fluorescens2 gcbc
40c3hvaA_



not modelled 94.9 18
PDB header:transferase
Chain: A: PDB Molecule:protein fimx;
PDBTitle: crystal structure of fimx ggdef domain from pseudomonas aeruginosa
41c4h54B_



not modelled 94.8 17
PDB header:transferase
Chain: B: PDB Molecule:diguanylate cyclase ydeh;
PDBTitle: crystal structure of the diguanylate cyclase dgcz
42c6eibC_



not modelled 94.6 12
PDB header:transferase
Chain: C: PDB Molecule:sensory box/ggdef family protein;
PDBTitle: structure of the active ggeef domain of a diguanylate cyclase from2 vibrio cholerae.
43c4ymeA_



not modelled 94.0 17
PDB header:lyase
Chain: A: PDB Molecule:sensory box/ggdef family protein;
PDBTitle: crystal structure of a sensory box/ggdef family protein (cc_0091) from2 caulobacter crescentus cb15 at 1.40 a resolution (psi community3 target, shapiro)
44c3i5bA_



not modelled 93.9 24
PDB header:signaling protein
Chain: A: PDB Molecule:wspr response regulator;
PDBTitle: crystal structure of the isolated ggdef domain of wpsr from2 pseudomonas aeruginosa
45c4zvhB_



not modelled 93.7 15
PDB header:signaling protein
Chain: B: PDB Molecule:diguanylate cyclase dosc;
PDBTitle: crystal structure of ggdef domain of the e. coli dosc - form iv
46c3iclA_



not modelled 93.6 20
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:eal/ggdef domain protein;
PDBTitle: x-ray structure of protein (eal/ggdef domain protein) from2 m.capsulatus, northeast structural genomics consortium target mcr174c
47c4w8yA_



not modelled 93.5 11
PDB header:rna binding protein
Chain: A: PDB Molecule:crispr system cmr subunit cmr2;
PDBTitle: structure of full length cmr2 from pyrococcus furiosus (manganese2 bound form)
48c4euvA_



not modelled 92.9 10
PDB header:signaling protein
Chain: A: PDB Molecule:peld;
PDBTitle: crystal structure of peld 158-ct from pseudomonas aeruginosa pao1, in2 complex with c-di-gmp, form 1
49c4zmmB_



not modelled 92.5 13
PDB header:transferase
Chain: B: PDB Molecule:diguanylate cyclase;
PDBTitle: ggdef domain of dcsbis complexed with c-di-gmp
50d1w25a3



not modelled 92.5 13
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:GGDEF domain
51c3ungC_



not modelled 92.3 14
PDB header:unknown function
Chain: C: PDB Molecule:cmr2dhd;
PDBTitle: structure of the cmr2 subunit of the crispr rna silencing complex
52c4iobA_



not modelled 92.2 18
PDB header:lyase
Chain: A: PDB Molecule:diguanylate cyclase tpbb;
PDBTitle: crystal structure of the ggdef domain of pa1120 (yfin or tpbb) from2 pseudomonas aeruginosa at 2.7 ang.
53c4urgB_



not modelled 90.2 15
PDB header:lyase
Chain: B: PDB Molecule:diguanylate cyclase;
PDBTitle: crystal structure of ggdef domain from t.maritima (active-like dimer)
54c3qyyB_



not modelled 90.0 14
PDB header:signaling protein/inhibitor
Chain: B: PDB Molecule:response regulator;
PDBTitle: a novel interaction mode between a microbial ggdef domain and the bis-2 (3, 5 )-cyclic di-gmp
55c5m3cB_



not modelled 88.7 17
PDB header:hydrolase
Chain: B: PDB Molecule:diguanylate cyclase;
PDBTitle: structure of the hybrid domain (ggdef-eal) of pa0575 from pseudomonas2 aeruginosa pao1 at 2.8 ang. with gtp and ca2+ bound to the active3 site of the ggdef domain
56c4dmzB_



not modelled 86.4 13
PDB header:nucleotide-binding protein
Chain: B: PDB Molecule:putative uncharacterized protein peld;
PDBTitle: peld 156-455 from pseudomonas aeruginosa pa14, apo form
57c3tvkA_



not modelled 82.7 16
PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase dgcz;
PDBTitle: diguanylate cyclase domain of dgcz
58c5xgdA_



not modelled 78.4 20
PDB header:transcription
Chain: A: PDB Molecule:uncharacterized protein pa0861;
PDBTitle: crystal structure of the pas-ggdef-eal domain of pa0861 from2 pseudomonas aeruginosa in complex with gtp
59c3pjwA_



not modelled 69.1 15
PDB header:lyase
Chain: A: PDB Molecule:cyclic dimeric gmp binding protein;
PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23
60d1v6ta_



not modelled 55.7 15
Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:LamB/YcsF-like
61c2x5eA_



not modelled 51.4 20
PDB header:unknown function
Chain: A: PDB Molecule:upf0271 protein pa4511;
PDBTitle: crystal structure of the hypothetical protein pa4511 from2 pseudomonas aeruginosa
62d2dfaa1



not modelled 50.8 22
Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:LamB/YcsF-like
63c6ifnA_



not modelled 48.8 8
PDB header:rna binding protein
Chain: A: PDB Molecule:type iii-a crispr-associated protein csm1;
PDBTitle: crystal structure of type iii-a crispr csm complex
64c4rnhA_



not modelled 30.8 18
PDB header:transferase, hydrolase
Chain: A: PDB Molecule:motility regulator;
PDBTitle: pamora tandem diguanylate cyclase - phosphodiesterase, c-di-gmp2 complex
65c2y0fD_



not modelled 26.4 25
PDB header:oxidoreductase
Chain: D: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase;
PDBTitle: structure of gcpe (ispg) from thermus thermophilus hb27
66d2fiua1



not modelled 24.3 12
Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Atu0297-like
67d1veha_



not modelled 23.3 13
Fold:Alpha-lytic protease prodomain-like
Superfamily:Fe-S cluster assembly (FSCA) domain-like
Family:NifU C-terminal domain-like
68c3lo3E_



not modelled 20.1 19
PDB header:structure genomics, unknown function
Chain: E: PDB Molecule:uncharacterized conserved protein;
PDBTitle: the crystal structure of a conserved functionally unknown protein from2 colwellia psychrerythraea 34h.
69c5buzC_



not modelled 14.1 12
PDB header:transport protein
Chain: C: PDB Molecule:snap receptor-like protein;
PDBTitle: crystal structure of a complex between the snare vam3 and the hops2 vps33-vps16 subcomplex from chaetomium thermophilum
70c4lrvL_



not modelled 10.6 55
PDB header:dna binding protein
Chain: L: PDB Molecule:dna sulfur modification protein dnde;
PDBTitle: crystal structure of dnde from escherichia coli b7a involved in dna2 phosphorothioation modification
71c3a9qR_



not modelled 9.8 18
PDB header:oxidoreductase
Chain: R: PDB Molecule:
PDBTitle: crystal structure analysis of e173a variant of the soybean2 ferritin sfer4
72c3bdkB_



not modelled 9.8 12
PDB header:lyase
Chain: B: PDB Molecule:d-mannonate dehydratase;
PDBTitle: crystal structure of streptococcus suis mannonate2 dehydratase complexed with substrate analogue
73c3dcaC_



not modelled 9.7 14
PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:rpa0582;
PDBTitle: crystal structure of the rpa0582- protein of unknown2 function from rhodopseudomonas palustris- a structural3 genomics target
74c2dgxA_



not modelled 9.6 15
PDB header:rna binding protein
Chain: A: PDB Molecule:kiaa0430 protein;
PDBTitle: solution structure of the rna recognition motif in kiaa04302 protein
75c6iqwA_



not modelled 8.9 7
PDB header:rna binding protein/rna
Chain: A: PDB Molecule:csm1;
PDBTitle: cryo-em structure of csm effector complex
76d1p42a1



not modelled 7.8 50
Fold:Ribosomal protein S5 domain 2-like
Superfamily:Ribosomal protein S5 domain 2-like
Family:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC
77d1gmnb1



not modelled 7.2 26
Fold:Hairpin loop containing domain-like
Superfamily:Hairpin loop containing domain-like
Family:Hairpin loop containing domain
78c2diuA_



not modelled 6.7 21
PDB header:rna binding protein
Chain: A: PDB Molecule:kiaa0430 protein;
PDBTitle: solution structure of the rrm domain of kiaa0430 protein
79d1mbma_



not modelled 6.6 57
Fold:Trypsin-like serine proteases
Superfamily:Trypsin-like serine proteases
Family:Viral proteases
80d2al1a1



not modelled 6.2 21
Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:Enolase
81c6f0kD_



not modelled 6.2 29
PDB header:membrane protein
Chain: D: PDB Molecule:actd;
PDBTitle: alternative complex iii
82c3nzkB_



not modelled 6.0 42
PDB header:hydrolase
Chain: B: PDB Molecule:udp-3-o-[3-hydroxymyristoyl] n-acetylglucosamine
PDBTitle: structure of lpxc from yersinia enterocolitica complexed with chir0902 inhibitor
83d1xhja_



not modelled 5.9 14
Fold:Alpha-lytic protease prodomain-like
Superfamily:Fe-S cluster assembly (FSCA) domain-like
Family:NifU C-terminal domain-like

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