1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	R	I	E	A	L	P	T	H	I	K	A	Q	V	L	A	E	A	L	P	W	L	K	Q	L	H	G	K	V	V	V	V	K	Y	G	G	N	A	M	T	D	D	T	L	R	R	A	F	A	A	D	M	A	F	L	R	N	C	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	H	P	V	V	V	H	G	G	G	P	Q	I	T	A	M	L	R	R	L	G	I	E	G	D	F	K	G	G	F	R	V	T	T	P	E	V	L	D	V	A	R	M	V	L	F	G	Q	V	G	R	E	L	V	N	L	I	N	A	H
Secondary structure
SS confidence
Disorder																							?		?	?	?	?	?																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	P	Y	A	V	G	I	T	G	E	D	A	Q	L	F	T	A	V	R	R	S	V	T	V	D	G	V	A	T	D	I	G	L	V	G	D	V	D	Q	V	N	T	A	A	M	L	D	L	V	A	A	G	R	I	P	V	V	S	T	L
Secondary structure
SS confidence
Disorder																						?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	P	D	A	D	G	V	V	H	N	I	N	A	D	T	A	A	A	A	V	A	E	A	L	G	A	E	K	L	L	M	L	T	D	I	D	G	L	Y	T	R	W	P	D	R	D	S	L	V	S	E	I	D	T	G	T	L	A	Q	L
Secondary structure
SS confidence
Disorder																																												?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.
Sequence		L	P	T	L	E	S	G	M	V	P	K	V	E	A	C	L	R	A	V	I	G	G	V	P	S	A	H	I	I	D	G	R	V	T	H	C	V	L	V	E	L	F	T	D	A	G	T	G	T	K	V	V	R	G
Secondary structure
SS confidence
Disorder																																																					?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 10%) Alpha helix ( 45%) Beta strand ( 17%)

Rank Aligned region

PDB 2ap9 chain A domain 1 Region: 4 - 294 Aligned: 291 Modelled: 291 Confidence: 100.0% Identity: 97% Fold: Carbamate kinase-like Superfamily: Carbamate kinase-like Family: N-acetyl-l-glutamate kinase Phyre2 PDB 2r98 chain A Region: 12 - 293 Aligned: 269 Modelled: 282 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:putative acetylglutamate synthase; PDBTitle: crystal structure of n-acetylglutamate synthase (selenomet2 substituted) from neisseria gonorrhoeae Phyre2 PDB 2buf chain A domain 1 Region: 12 - 294 Aligned: 278 Modelled: 283 Confidence: 100.0% Identity: 48% Fold: Carbamate kinase-like Superfamily: Carbamate kinase-like Family: N-acetyl-l-glutamate kinase Phyre2 PDB 2rd5 chain A Region: 10 - 293 Aligned: 279 Modelled: 284 Confidence: 100.0% Identity: 42% PDB header:protein binding Chain: A: PDB Molecule:acetylglutamate kinase-like protein; PDBTitle: structural basis for the regulation of n-acetylglutamate kinase by pii2 in arabidopsis thaliana Phyre2 PDB 2v5h chain B Region: 12 - 294 Aligned: 277 Modelled: 283 Confidence: 100.0% Identity: 45% PDB header:transcription Chain: B: PDB Molecule:acetylglutamate kinase; PDBTitle: controlling the storage of nitrogen as arginine: the2 complex of pii and acetylglutamate kinase from3 synechococcus elongatus pcc 7942 Phyre2 PDB 2bty chain A domain 1 Region: 9 - 294 Aligned: 277 Modelled: 286 Confidence: 100.0% Identity: 42% Fold: Carbamate kinase-like Superfamily: Carbamate kinase-like Family: N-acetyl-l-glutamate kinase Phyre2 PDB 3zzg chain C Region: 16 - 294 Aligned: 266 Modelled: 276 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: C: PDB Molecule:acetylglutamate kinase; PDBTitle: crystal structure of the amino acid kinase domain from saccharomyces2 cerevisiae acetylglutamate kinase without ligands Phyre2 PDB 4ab7 chain C Region: 16 - 294 Aligned: 264 Modelled: 276 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: C: PDB Molecule:protein arg5,6, mitochondrial; PDBTitle: crystal structure of a tetrameric acetylglutamate kinase from2 saccharomyces cerevisiae complexed with its substrate n-3 acetylglutamate Phyre2 PDB 3s7y chain X Region: 17 - 294 Aligned: 262 Modelled: 278 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: X: PDB Molecule:n-acetylglutamate kinase / n-acetylglutamate synthase; PDBTitle: crystal structure of mmnags in space group p3121 at 4.3 a resolution Phyre2 PDB 1gs5 chain A Region: 29 - 292 Aligned: 252 Modelled: 264 Confidence: 100.0% Identity: 26% Fold: Carbamate kinase-like Superfamily: Carbamate kinase-like Family: N-acetyl-l-glutamate kinase Phyre2 PDB 3s6k chain A Region: 17 - 294 Aligned: 265 Modelled: 275 Confidence: 100.0% Identity: 32% PDB header:transferase Chain: A: PDB Molecule:acetylglutamate kinase; PDBTitle: crystal structure of xcnags Phyre2 PDB 2egx chain A Region: 30 - 292 Aligned: 238 Modelled: 257 Confidence: 100.0% Identity: 34% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative acetylglutamate kinase; PDBTitle: crystal structure of the putative acetylglutamate kinase from thermus2 thermophilus Phyre2 PDB 3l86 chain A Region: 28 - 278 Aligned: 239 Modelled: 245 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:acetylglutamate kinase; PDBTitle: the crystal structure of smu.665 from streptococcus mutans ua159 Phyre2 PDB 1e19 chain A Region: 28 - 293 Aligned: 261 Modelled: 266 Confidence: 100.0% Identity: 23% Fold: Carbamate kinase-like Superfamily: Carbamate kinase-like Family: Carbamate kinase Phyre2 PDB 1b7b chain A Region: 28 - 291 Aligned: 261 Modelled: 264 Confidence: 100.0% Identity: 22% Fold: Carbamate kinase-like Superfamily: Carbamate kinase-like Family: Carbamate kinase Phyre2 PDB 4axs chain A Region: 30 - 292 Aligned: 259 Modelled: 263 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: A: PDB Molecule:carbamate kinase; PDBTitle: structure of carbamate kinase from mycoplasma penetrans Phyre2 PDB 2e9y chain A Region: 28 - 294 Aligned: 262 Modelled: 267 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:carbamate kinase; PDBTitle: crystal structure of project ape1968 from aeropyrum pernix k1 Phyre2 PDB 3kzf chain C Region: 27 - 293 Aligned: 260 Modelled: 267 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: C: PDB Molecule:carbamate kinase; PDBTitle: structure of giardia carbamate kinase Phyre2 PDB 2j5t chain F Region: 28 - 293 Aligned: 234 Modelled: 248 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: F: PDB Molecule:glutamate 5-kinase; PDBTitle: glutamate 5-kinase from escherichia coli complexed with2 glutamate Phyre2 PDB 2w21 chain A Region: 28 - 293 Aligned: 235 Modelled: 241 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:glutamate 5-kinase; PDBTitle: crystal structure of the aminoacid kinase domain of the2 glutamate 5 kinase of escherichia coli. Phyre2 1 d2ap9a1 2 c2r98A_ 3 d2bufa1 4 c2rd5A_ 5 c2v5hB_ 6 d2btya1 7 c3zzgC_ 8 c4ab7C_ 9 c3s7yX_ 10 d1gs5a_ 11 c3s6kA_ 12 c2egxA_ 13 c3l86A_ 14 d1e19a_ 15 d1b7ba_ 16 c4axsA_ 17 c2e9yA_ 18 c3kzfC_ 19 c2j5tF_ 20 c2w21A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99