1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	R	V	R	R	G	T	E	L	L	L	S	P	Q	S	P	P	A	T	G	G	L	I	V	L	T	G	L	R	L	L	A	G	L	I	W	L	Y	N	V	V	W	K	V	P	P	D	F	G	E	R	G	R	R	D	L	Y	H	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?			?	?		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	H	L	A	V	E	H	P	V	F	T	P	F	S	W	V	I	E	H	A	V	L	P	Y	F	T	A	F	G	W	G	V	L	F	A	E	S	A	L	A	V	L	L	L	T	G	T	A	V	R	L	A	A	L	I	G	I	G	Q	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	A	I	G	L	S	V	A	E	S	P	G	E	W	P	W	A	Y	A	M	L	L	G	I	H	V	V	L	L	F	T	C	S	T	R	Y	A	A	V	D	A	V	R	A	A	A	T	G	S	A	A	R	T	A	A	Q	R	L	L	A
Secondary structure
SS confidence
Disorder																																												?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	W	G	I	V	L	G	L	I	G	L	V	A	V	W	R	G	L	G	D	D	R	P	A	Y	V	G	I	R	A	L	E	F	S	L	G	E	Y	N	L	R	G	A	L	A	L	I	A	I	A	L	A	M	L	A	A	A	K	R	G
Secondary structure
SS confidence
Disorder																																																									?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		W	R	T	V	A	L	V	A	A	V	V	A	V	A	A	A	A	A	I	Y	L	Q	V	G	R	T	A	V	W	L	G	G	T	N	T	T	A	A	V	F	V	C	A	A	V	V	S	L	A	T	E	F	R	I	G	R	V	E	G	A
Secondary structure
SS confidence
Disorder																																																							?	?	?	?	?	?	?
Disorder confidence
Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 11%) Alpha helix ( 81%) Beta strand ( 2%) TM helix ( 48%) (View membrane topology prediction)

Rank Aligned region

PDB 3k2k chain A Region: 129 - 148 Aligned: 20 Modelled: 20 Confidence: 23.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:putative carboxypeptidase; PDBTitle: crystal structure of putative carboxypeptidase (yp_103406.1) from2 burkholderia mallei atcc 23344 at 2.49 a resolution Phyre2 PDB 3l2n chain A Region: 129 - 148 Aligned: 20 Modelled: 20 Confidence: 21.9% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:peptidase m14, carboxypeptidase a; PDBTitle: crystal structure of putative carboxypeptidase a (yp_562911.1) from2 shewanella denitrificans os-217 at 2.39 a resolution Phyre2 PDB 5lnk chain N Region: 37 - 52 Aligned: 16 Modelled: 16 Confidence: 21.8% Identity: 25% PDB header:oxidoreductase Chain: N: PDB Molecule:mitochondrial complex i, nd2 subunit; PDBTitle: entire ovine respiratory complex i Phyre2 PDB 5t2x chain C Region: 123 - 160 Aligned: 32 Modelled: 38 Confidence: 18.7% Identity: 22% PDB header:unknown function Chain: C: PDB Molecule:uncharacterized protein lpg1670; PDBTitle: crystal structure of uncharacterised protein lpg1670 Phyre2 PDB 2hnt chain C Region: 130 - 136 Aligned: 7 Modelled: 7 Confidence: 14.7% Identity: 43% PDB header:serine protease Chain: C: PDB Molecule:gamma-thrombin; PDBTitle: crystallographic structure of human gamma-thrombin Phyre2 PDB 4ywc chain A Region: 16 - 56 Aligned: 41 Modelled: 41 Confidence: 14.4% Identity: 20% PDB header:transcription regulator Chain: A: PDB Molecule:transcription factor myc3; PDBTitle: crystal structure of myc3(5-242) fragment in complex with jaz9(218-2 239) peptide Phyre2 PDB 4xe4 chain A Region: 130 - 136 Aligned: 7 Modelled: 7 Confidence: 14.1% Identity: 29% PDB header:blood clotting Chain: A: PDB Molecule:coagulation factor xii; PDBTitle: coagulation factor xii protease domain crystal structure Phyre2 PDB 4er8 chain A Region: 126 - 137 Aligned: 12 Modelled: 12 Confidence: 13.5% Identity: 17% PDB header:dna binding protein/dna Chain: A: PDB Molecule:tnparep for protein; PDBTitle: structure of the rep associates tyrosine transposase bound to a rep2 hairpin Phyre2 PDB 2lcy chain A Region: 49 - 69 Aligned: 21 Modelled: 21 Confidence: 11.9% Identity: 10% PDB header:viral protein Chain: A: PDB Molecule:virion spike glycoprotein; PDBTitle: nmr structure of the complete internal fusion loop from ebolavirus gp22 at ph 5.5 Phyre2 PDB 5uqy chain B Region: 48 - 73 Aligned: 26 Modelled: 26 Confidence: 11.8% Identity: 12% PDB header:viral protein/immune system Chain: B: PDB Molecule:envelope glycoprotein gp2; PDBTitle: crystal structure of marburg virus gp in complex with the human2 survivor antibody mr78 Phyre2 PDB 2asu chain B Region: 130 - 136 Aligned: 7 Modelled: 7 Confidence: 11.0% Identity: 57% PDB header:hydrolase Chain: B: PDB Molecule:hepatocyte growth factor-like protein; PDBTitle: crystal structure of the beta-chain of hgfl/msp Phyre2 PDB 1q90 chain G Region: 182 - 189 Aligned: 8 Modelled: 8 Confidence: 10.6% Identity: 75% PDB header:photosynthesis Chain: G: PDB Molecule:cytochrome b6f complex subunit petg; PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii Phyre2 PDB 1q90 chain G Region: 182 - 189 Aligned: 8 Modelled: 8 Confidence: 10.6% Identity: 75% Fold: Single transmembrane helix Superfamily: PetG subunit of the cytochrome b6f complex Family: PetG subunit of the cytochrome b6f complex Phyre2 PDB 5e4v chain A Region: 130 - 140 Aligned: 11 Modelled: 11 Confidence: 9.8% Identity: 64% PDB header:viral protein Chain: A: PDB Molecule:nucleoprotein,phosphoprotein; PDBTitle: crystal structure of measles n0-p complex Phyre2 PDB 2bs2 chain C domain 1 Region: 100 - 209 Aligned: 110 Modelled: 110 Confidence: 9.5% Identity: 18% Fold: Heme-binding four-helical bundle Superfamily: Fumarate reductase respiratory complex transmembrane subunits Family: Fumarate reductase respiratory complex cytochrome b subunit, FrdC Phyre2 PDB 4uft chain B Region: 130 - 140 Aligned: 11 Modelled: 11 Confidence: 9.3% Identity: 64% PDB header:rna binding protein Chain: B: PDB Molecule:nucleoprotein; PDBTitle: structure of the helical measles virus nucleocapsid Phyre2 PDB 4v1l chain C Region: 43 - 48 Aligned: 6 Modelled: 6 Confidence: 9.2% Identity: 83% PDB header:sugar binding protein Chain: C: PDB Molecule:carbohydrate binding module; PDBTitle: high resolution structure of a novel carbohydrate binding module from2 glycoside hydrolase family 9 (cel9a) from ruminococcus flavefaciens3 fd-1 Phyre2 PDB 5dz7 chain A Region: 149 - 240 Aligned: 87 Modelled: 92 Confidence: 9.2% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:polyketide biosynthesis protein pkse; PDBTitle: structural basis of acyl transfer in a trans-at polyketide synthase Phyre2 PDB 1qmh chain A domain 2 Region: 67 - 89 Aligned: 23 Modelled: 23 Confidence: 8.8% Identity: 17% Fold: IF3-like Superfamily: EPT/RTPC-like Family: RNA 3'-terminal phosphate cyclase, RPTC Phyre2 PDB 4o9p chain C Region: 39 - 47 Aligned: 9 Modelled: 9 Confidence: 8.7% Identity: 33% PDB header:membrane protein Chain: C: PDB Molecule:nad(p) transhydrogenase subunit alpha 2; PDBTitle: crystal structure of thermus thermophilis transhydrogeanse domain ii2 dimer semet derivative Phyre2 1 c3k2kA_ 2 c3l2nA_ 3 c5lnkn_ 4 c5t2xC_ 5 c2hntC_ 6 c4ywcA_ 7 c4xe4A_ 8 c4er8A_ 9 c2lcyA_ 10 c5uqyB_ 11 c2asuB_ 12 c1q90G_ 13 d1q90g_ 14 c5e4vA_ 15 d2bs2c1 16 c4uftB_ 17 c4v1lC_ 18 c5dz7A_ 19 d1qmha2 20 c4o9pC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59