1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	A	H	T	H	D	G	T	R	T	W	R	T	G	R	Q	A	T	T	L	L	A	L	L	A	G	V	F	G	G	A	A	S	C	A	A	P	I	Q	A	D	M	M	G	N	A	F	L	T	A	L	T	N	A	G	I	A	Y	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?									?																			?				?				?	?	?										?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	P	A	T	T	V	A	L	G	R	S	V	C	P	M	V	V	A	P	G	G	T	F	E	S	I	T	S	R	M	A	E	I	N	G	M	S	R	D	M	A	S	T	F	T	I	V	A	I	G	T	Y	C	P	A	V	I	A	P	L
Secondary structure
SS confidence
Disorder																			?	?	?	?	?										?		?	?	?	?																						?	?
Disorder confidence
		.	.	.	.	.	.	.
Sequence		M	P	N	R	L	Q	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 27%) Alpha helix ( 67%) Beta strand ( 0%) TM helix ( 13%) (View membrane topology prediction)

Rank Aligned region

PDB 2csu chain A domain 3 Region: 42 - 68 Aligned: 27 Modelled: 27 Confidence: 27.4% Identity: 19% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 PDB 1mke chain A domain 1 Region: 56 - 78 Aligned: 23 Modelled: 23 Confidence: 19.6% Identity: 4% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 5uqd chain A Region: 45 - 60 Aligned: 16 Modelled: 16 Confidence: 14.3% Identity: 31% PDB header:oxidoreductase Chain: A: PDB Molecule:dumpy: shorter than wild-type; PDBTitle: dpy-21 in complex with fe(ii) and alpha-ketoglutarate Phyre2 PDB 2ifs chain A Region: 55 - 81 Aligned: 27 Modelled: 27 Confidence: 13.3% Identity: 4% PDB header:signaling protein Chain: A: PDB Molecule:wiskott-aldrich syndrome protien interacting protein and PDBTitle: structure of the n-wasp evh1 domain in complex with an extended wip2 peptide Phyre2 PDB 6c3r chain B Region: 73 - 124 Aligned: 51 Modelled: 52 Confidence: 11.3% Identity: 10% PDB header:viral protein Chain: B: PDB Molecule:cricket paralysis virus 1a protein; PDBTitle: cricket paralysis virus rnai suppressor protein crpv-1a Phyre2 PDB 1xod chain A domain 1 Region: 56 - 77 Aligned: 22 Modelled: 22 Confidence: 8.4% Identity: 23% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 1nye chain D Region: 58 - 114 Aligned: 56 Modelled: 57 Confidence: 8.2% Identity: 16% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 3ss4 chain C Region: 47 - 62 Aligned: 16 Modelled: 16 Confidence: 6.7% Identity: 38% PDB header:hydrolase Chain: C: PDB Molecule:glutaminase c; PDBTitle: crystal structure of mouse glutaminase c, phosphate-bound form Phyre2 PDB 1euc chain B domain 1 Region: 46 - 72 Aligned: 27 Modelled: 27 Confidence: 6.6% Identity: 22% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 PDB 5dgg chain B Region: 37 - 58 Aligned: 22 Modelled: 22 Confidence: 6.1% Identity: 23% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: central domain of uncharacterized lpg1148 protein from legionella2 pneumophila Phyre2 PDB 2lwe chain A Region: 46 - 60 Aligned: 15 Modelled: 15 Confidence: 6.1% Identity: 13% PDB header:signaling protein Chain: A: PDB Molecule:probable atp-dependent rna helicase ddx58; PDBTitle: solution structure of mutant (t170e) second card of human rig-i Phyre2 PDB 5h75 chain B Region: 49 - 105 Aligned: 54 Modelled: 57 Confidence: 6.0% Identity: 11% PDB header:lyase Chain: B: PDB Molecule:mersacidin decarboxylase,immunoglobulin g-binding protein PDBTitle: crystal structure of the mrsd-protein a fusion protein Phyre2 PDB 1vjq chain B Region: 48 - 59 Aligned: 12 Modelled: 11 Confidence: 6.0% Identity: 42% PDB header:structural genomics, de novo protein Chain: B: PDB Molecule:designed protein; PDBTitle: designed protein based on backbone conformation of2 procarboxypeptidase-a (1aye) with sidechains chosen for maximal3 predicted stability. Phyre2 1 d2csua3 2 d1mkea1 3 c5uqdA_ 4 c2ifsA_ 5 c6c3rB_ 6 d1xoda1 7 d1nyed_ 8 c3ss4C_ 9 d1eucb1 10 c5dggB_ 11 c2lweA_ 12 c5h75B_ 13 c1vjqB_