1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	F	A	W	P	L	G	A	A	E	S	T	L	E	F	Y	D	L	S	H	P	W	G	H	G	A	P	A	W	P	Y	F	E	D	V	Q	I	E	R	L	H	G	M	A	K	S	R	V	L	T	Q	K	I	T	T	V	M	H	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	T	H	I	D	A	P	A	H	V	V	E	G	T	P	F	L	D	E	I	P	L	S	A	F	F	G	T	G	V	V	V	S	I	P	K	G	K	W	G	M	V	T	A	E	D	L	Q	N	A	T	P	D	I	R	P	G	D	I	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	V	N	T	G	W	H	H	K	Y	A	D	S	A	E	Y	Y	A	Y	S	P	G	F	D	K	K	A	G	E	W	F	A	A	K	G	V	K	A	V	G	T	D	T	Q	A	L	D	H	P	L	A	T	A	I	A	P	H	S	P	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	A	Q	G	G	L	L	P	W	A	V	R	E	Y	E	A	Q	T	G	R	K	V	L	D	D	F	P	D	W	E	P	C	H	R	A	I	L	S	Q	G	I	Y	G	F	E	N	V	G	G	D	L	D	K	V	T	G	K	R	V	T
Secondary structure
SS confidence
Disorder													?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.
Sequence		F	A	A	F	P	W	R	W	V	G	G	D	G	C	I	V	R	L	V	A	I	V	D	P	T	G	S	Y	R	I	E	T	G	K	A	V
Secondary structure
SS confidence
Disorder																												?			?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 8%) Alpha helix ( 17%) Beta strand ( 26%) TM helix ( 6%) (View membrane topology prediction)

Rank Aligned region

PDB 5nna chain B Region: 10 - 263 Aligned: 221 Modelled: 222 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: B: PDB Molecule:isatin hydrolase a; PDBTitle: isatin hydrolase a (iha) from labrenzia aggregata bound to benzyl2 benzoate Phyre2 PDB 4j0n chain A Region: 10 - 263 Aligned: 221 Modelled: 222 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:isatin hydrolase b; PDBTitle: crystal structure of a manganese dependent isatin hydrolase Phyre2 PDB 5nmp chain F Region: 12 - 263 Aligned: 219 Modelled: 220 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: F: PDB Molecule:isatin hydrolase; PDBTitle: isatin hydrolase a (iha) from ralstonia solanacearum Phyre2 PDB 4coa chain A Region: 13 - 261 Aligned: 204 Modelled: 213 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:kynurenine formamidase; PDBTitle: crystal structure of kynurenine formamidase from bacillus2 anthracis complexed with 2-aminoacetophenone. Phyre2 PDB 1r61 chain A Region: 12 - 261 Aligned: 203 Modelled: 213 Confidence: 100.0% Identity: 27% Fold: The "swivelling" beta/beta/alpha domain Superfamily: Putative cyclase Family: Putative cyclase Phyre2 PDB 4cog chain B Region: 16 - 264 Aligned: 205 Modelled: 213 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: B: PDB Molecule:kynurenine formamidase; PDBTitle: crystal structure of kynurenine formamidase from burkholderia2 cenocepacia Phyre2 PDB 4cob chain A Region: 15 - 264 Aligned: 205 Modelled: 214 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:kynurenine formamidase; PDBTitle: crystal structure kynurenine formamidase from pseudomonas aeruginosa Phyre2 PDB 2b0a chain A domain 1 Region: 15 - 263 Aligned: 186 Modelled: 208 Confidence: 100.0% Identity: 26% Fold: The "swivelling" beta/beta/alpha domain Superfamily: Putative cyclase Family: Putative cyclase Phyre2 PDB 5ibz chain D Region: 13 - 261 Aligned: 210 Modelled: 210 Confidence: 100.0% Identity: 30% PDB header:lyase Chain: D: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a novel cyclase (pfam04199). Phyre2 PDB 2fvt chain A domain 1 Region: 85 - 165 Aligned: 69 Modelled: 81 Confidence: 80.6% Identity: 22% Fold: MTH938-like Superfamily: MTH938-like Family: MTH938-like Phyre2 PDB 2gm2 chain A Region: 88 - 165 Aligned: 64 Modelled: 78 Confidence: 57.1% Identity: 13% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: nmr structure of xanthomonas campestris xcc1710: northeast2 structural genomics consortium target xcr35 Phyre2 PDB 1zy9 chain A domain 2 Region: 102 - 158 Aligned: 56 Modelled: 57 Confidence: 46.5% Identity: 11% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: YicI catalytic domain-like Phyre2 PDB 5ir2 chain A Region: 84 - 167 Aligned: 74 Modelled: 84 Confidence: 42.3% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:cellulase; PDBTitle: crystal structure of novel cellulases from microbes associated with2 the gut ecosystem Phyre2 PDB 2k2e chain A Region: 85 - 165 Aligned: 69 Modelled: 81 Confidence: 40.4% Identity: 32% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein bp2786; PDBTitle: solution nmr structure of bordetella pertussis protein2 bp2786, a mth938-like domain. northeast structural3 genomics consortium target ber31 Phyre2 PDB 3e4f chain B Region: 101 - 128 Aligned: 28 Modelled: 28 Confidence: 39.3% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:aminoglycoside n3-acetyltransferase; PDBTitle: crystal structure of ba2930- a putative aminoglycoside n3-2 acetyltransferase from bacillus anthracis Phyre2 PDB 2nyg chain A domain 1 Region: 99 - 128 Aligned: 30 Modelled: 30 Confidence: 38.1% Identity: 13% Fold: TTHA0583/YokD-like Superfamily: TTHA0583/YokD-like Family: Aminoglycoside 3-N-acetyltransferase-like Phyre2 PDB 3sma chain D Region: 99 - 128 Aligned: 30 Modelled: 30 Confidence: 37.9% Identity: 23% PDB header:transferase Chain: D: PDB Molecule:frbf; PDBTitle: a new n-acetyltransferase fold in the structure and mechanism of the2 phosphonate biosynthetic enzyme frbf Phyre2 PDB 4ce0 chain A Region: 103 - 157 Aligned: 42 Modelled: 55 Confidence: 37.6% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:o-methyltransferase; PDBTitle: crystal structure of sah-bound spinosyn rhamnosyl 4'-o-2 methyltransferase spnh from saccharopolyspora spinosa Phyre2 PDB 2q4q chain A domain 1 Region: 97 - 165 Aligned: 56 Modelled: 69 Confidence: 37.2% Identity: 13% Fold: MTH938-like Superfamily: MTH938-like Family: MTH938-like Phyre2 PDB 4zgw chain B Region: 116 - 162 Aligned: 33 Modelled: 47 Confidence: 36.8% Identity: 21% PDB header:oxidoreductase Chain: B: PDB Molecule:short-chain dehydrogenase/reductase; PDBTitle: short-chain dehydrogenase/reductase from serratia marcescens bcrc2 10948 Phyre2 1 c5nnaB_ 2 c4j0nA_ 3 c5nmpF_ 4 c4coaA_ 5 d1r61a_ 6 c4cogB_ 7 c4cobA_ 8 d2b0aa1 9 c5ibzD_ 10 d2fvta1 11 c2gm2A_ 12 d1zy9a2 13 c5ir2A_ 14 c2k2eA_ 15 c3e4fB_ 16 d2nyga1 17 c3smaD_ 18 c4ce0A_ 19 d2q4qa1 20 c4zgwB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99