1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	A	T	T	R	D	R	E	G	A	T	M	I	T	F	R	L	R	L	P	C	R	T	I	L	R	V	F	S	R	N	P	L	V	R	G	T	D	R	L	E	A	V	V	M	L	L	A	V	T	V	S	L	L	T	I	P	F	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	A	A	G	T	A	V	Q	D	S	R	S	H	V	Y	A	H	Q	A	Q	T	R	H	P	A	T	A	T	V	I	D	H	E	G	V	I	D	S	N	T	T	A	T	S	A	P	P	R	T	K	I	T	V	P	A	R	W	V	V	N
Secondary structure
SS confidence
Disorder																					?	?											?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	I	E	R	S	G	E	V	N	A	K	P	G	T	K	S	G	D	R	V	G	I	W	V	D	S	A	G	Q	L	V	D	E	P	A	P	P	A	R	A	I	A	D	A	A	L	A	A	L	G	L	W	L	S	V	A	A	V	A	G
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?	?																	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence		A	L	L	A	L	T	R	A	I	L	I	R	V	R	N	A	S	W	Q	H	D	I	D	S	L	F	C	T	Q	R
Secondary structure
SS confidence
Disorder																											?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 28%) Alpha helix ( 46%) Beta strand ( 13%) TM helix ( 22%) (View membrane topology prediction)

Rank Aligned region

PDB 1hym chain B Region: 138 - 155 Aligned: 18 Modelled: 18 Confidence: 61.6% Identity: 44% PDB header:hydrolase (serine proteinase) Chain: B: PDB Molecule:hydrolyzed cucurbita maxima trypsin inhibitor v; PDBTitle: hydrolyzed trypsin inhibitor (cmti-v, minimized average nmr structure) Phyre2 PDB 1dwm chain A Region: 138 - 155 Aligned: 18 Modelled: 18 Confidence: 47.6% Identity: 33% Fold: CI-2 family of serine protease inhibitors Superfamily: CI-2 family of serine protease inhibitors Family: CI-2 family of serine protease inhibitors Phyre2 PDB 3rdy chain A Region: 138 - 155 Aligned: 18 Modelled: 18 Confidence: 45.5% Identity: 50% PDB header:hydrolase inhibitor Chain: A: PDB Molecule:bwi-1=protease inhibitor/trypsin inhibitor; PDBTitle: crystal structure of buckwheat trypsin inhibitor rbti at 1.84 angstrom2 resolution Phyre2 PDB 1vbw chain A Region: 138 - 154 Aligned: 17 Modelled: 17 Confidence: 45.0% Identity: 41% PDB header:protein binding Chain: A: PDB Molecule:trypsin inhibitor bgit; PDBTitle: crystal structure of bitter gourd trypsin inhibitor Phyre2 PDB 2sni chain I Region: 138 - 154 Aligned: 17 Modelled: 17 Confidence: 43.8% Identity: 35% Fold: CI-2 family of serine protease inhibitors Superfamily: CI-2 family of serine protease inhibitors Family: CI-2 family of serine protease inhibitors Phyre2 PDB 2ci2 chain I Region: 138 - 154 Aligned: 17 Modelled: 17 Confidence: 43.0% Identity: 35% PDB header:proteinase inhibitor (chymotrypsin) Chain: I: PDB Molecule:chymotrypsin inhibitor 2; PDBTitle: crystal and molecular structure of the serine proteinase inhibitor ci-2 2 from barley seeds Phyre2 PDB 2knc chain B Region: 165 - 201 Aligned: 37 Modelled: 37 Confidence: 41.3% Identity: 22% PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-3; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex Phyre2 PDB 1to2 chain I Region: 138 - 154 Aligned: 17 Modelled: 17 Confidence: 41.3% Identity: 35% Fold: CI-2 family of serine protease inhibitors Superfamily: CI-2 family of serine protease inhibitors Family: CI-2 family of serine protease inhibitors Phyre2 PDB 1ypc chain I Region: 138 - 154 Aligned: 17 Modelled: 17 Confidence: 40.7% Identity: 35% Fold: CI-2 family of serine protease inhibitors Superfamily: CI-2 family of serine protease inhibitors Family: CI-2 family of serine protease inhibitors Phyre2 PDB 1tin chain A Region: 138 - 155 Aligned: 18 Modelled: 18 Confidence: 38.8% Identity: 44% PDB header:serine protease inhibitor Chain: A: PDB Molecule:trypsin inhibitor v; PDBTitle: three-dimensional structure in solution of cucurbita maxima trypsin2 inhibitor-v determined by nmr spectroscopy Phyre2 PDB 1hji chain B Region: 191 - 199 Aligned: 9 Modelled: 9 Confidence: 24.9% Identity: 44% PDB header:bacteriophage hk022 Chain: B: PDB Molecule:nun-protein; PDBTitle: bacteriophage hk022 nun-protein-nutboxb-rna complex Phyre2 PDB 4tqv chain J Region: 32 - 66 Aligned: 35 Modelled: 35 Confidence: 22.9% Identity: 20% PDB header:transport protein Chain: J: PDB Molecule:algm2; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 1cse chain I Region: 138 - 154 Aligned: 17 Modelled: 17 Confidence: 20.9% Identity: 18% Fold: CI-2 family of serine protease inhibitors Superfamily: CI-2 family of serine protease inhibitors Family: CI-2 family of serine protease inhibitors Phyre2 PDB 3jt0 chain B Region: 120 - 154 Aligned: 35 Modelled: 35 Confidence: 19.8% Identity: 26% PDB header:structural protein Chain: B: PDB Molecule:lamin-b1; PDBTitle: crystal structure of the c-terminal fragment (426-558) lamin-b1 from2 homo sapiens, northeast structural genomics consortium target hr5546a Phyre2 PDB 2byo chain A domain 1 Region: 139 - 150 Aligned: 12 Modelled: 12 Confidence: 17.0% Identity: 17% Fold: LolA-like prokaryotic lipoproteins and lipoprotein localization factors Superfamily: Prokaryotic lipoproteins and lipoprotein localization factors Family: LppX-like Phyre2 PDB 4qa8 chain A Region: 139 - 156 Aligned: 18 Modelled: 18 Confidence: 16.8% Identity: 17% PDB header:lipid transport Chain: A: PDB Molecule:putative lipoprotein lprf; PDBTitle: crystal structure of lprf from mycobacterium bovis Phyre2 PDB 1em9 chain A Region: 185 - 209 Aligned: 25 Modelled: 25 Confidence: 14.5% Identity: 28% Fold: Retrovirus capsid protein, N-terminal core domain Superfamily: Retrovirus capsid protein, N-terminal core domain Family: Retrovirus capsid protein, N-terminal core domain Phyre2 PDB 1egl chain A Region: 138 - 154 Aligned: 17 Modelled: 17 Confidence: 13.9% Identity: 18% Fold: CI-2 family of serine protease inhibitors Superfamily: CI-2 family of serine protease inhibitors Family: CI-2 family of serine protease inhibitors Phyre2 PDB 1uv7 chain A Region: 135 - 146 Aligned: 12 Modelled: 12 Confidence: 13.4% Identity: 17% PDB header:transport Chain: A: PDB Molecule:general secretion pathway protein m; PDBTitle: periplasmic domain of epsm from vibrio cholerae Phyre2 PDB 1uv7 chain A Region: 135 - 146 Aligned: 12 Modelled: 12 Confidence: 13.4% Identity: 17% Fold: RRF/tRNA synthetase additional domain-like Superfamily: General secretion pathway protein M, EpsM Family: General secretion pathway protein M, EpsM Phyre2 1 c1hymB_ 2 d1dwma_ 3 c3rdyA_ 4 c1vbwA_ 5 d2snii_ 6 c2ci2I_ 7 c2kncB_ 8 d1to2i_ 9 d1ypci_ 10 c1tinA_ 11 c1hjiB_ 12 c4tqvJ_ 13 d1csei_ 14 c3jt0B_ 15 d2byoa1 16 c4qa8A_ 17 d1em9a_ 18 d1egla_ 19 c1uv7A_ 20 d1uv7a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50