1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	N	V	G	D	Q	G	V	D	A	V	F	G	V	I	Y	P	P	Q	V	A	L	V	S	F	G	K	P	A	Q	R	V	C	A	V	D	G	A	I	H	V	M	T	T	V	L	A	T	L	P	A	D	H	G	C	S	D	D	H
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80
Sequence		R	G	A	L	F	F	L	S	I	N	E	L	T	R	C	A	A	V	T	G
Secondary structure
SS confidence
Disorder																	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 16%) Alpha helix ( 21%) Beta strand ( 52%)

Rank Aligned region

PDB 1b5s chain A Region: 1 - 79 Aligned: 79 Modelled: 79 Confidence: 100.0% Identity: 25% Fold: CoA-dependent acyltransferases Superfamily: CoA-dependent acyltransferases Family: CAT-like Phyre2 PDB 4n72 chain B Region: 1 - 79 Aligned: 79 Modelled: 79 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:pyruvate dehydrogenase (dihydrolipoyltransacetylase PDBTitle: catalytic domain from dihydrolipoamide acetyltransferase of pyruvate2 dehydrogenase from escherichia coli Phyre2 PDB 3l60 chain A Region: 1 - 79 Aligned: 79 Modelled: 79 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: A: PDB Molecule:branched-chain alpha-keto acid dehydrogenase; PDBTitle: crystal structure of branched-chain alpha-keto acid dehydrogenase2 subunit e2 from mycobacterium tuberculosis Phyre2 PDB 1dpb chain A Region: 1 - 79 Aligned: 79 Modelled: 79 Confidence: 100.0% Identity: 16% Fold: CoA-dependent acyltransferases Superfamily: CoA-dependent acyltransferases Family: CAT-like Phyre2 PDB 2ii4 chain C Region: 1 - 79 Aligned: 79 Modelled: 79 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: C: PDB Molecule:lipoamide acyltransferase component of branched-chain PDBTitle: crystal structure of a cubic core of the dihydrolipoamide2 acyltransferase (e2b) component in the branched-chain alpha-ketoacid3 dehydrogenase complex (bckdc), coenzyme a-bound form Phyre2 PDB 3b8k chain A Region: 1 - 79 Aligned: 79 Modelled: 79 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase; PDBTitle: structure of the truncated human dihydrolipoyl acetyltransferase (e2) Phyre2 PDB 1scz chain A Region: 1 - 79 Aligned: 79 Modelled: 79 Confidence: 100.0% Identity: 27% Fold: CoA-dependent acyltransferases Superfamily: CoA-dependent acyltransferases Family: CAT-like Phyre2 PDB 3mae chain A Region: 1 - 80 Aligned: 80 Modelled: 80 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:2-oxoisovalerate dehydrogenase e2 component, PDBTitle: crystal structure of probable dihydrolipoamide acetyltransferase from2 listeria monocytogenes 4b f2365 Phyre2 PDB 6h60 chain A Region: 1 - 79 Aligned: 79 Modelled: 79 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate dehydrogenase protein x component, mitochondrial; PDBTitle: pseudo-atomic structural model of the e3bp component of the human2 pyruvate dehydrogenase multienzyme complex Phyre2 PDB 3rqc chain B Region: 1 - 79 Aligned: 71 Modelled: 79 Confidence: 99.9% Identity: 23% PDB header:transferase Chain: B: PDB Molecule:probable lipoamide acyltransferase; PDBTitle: crystal structure of the catalytic core of the 2-oxoacid dehydrogenase2 multienzyme complex from thermoplasma acidophilum Phyre2 PDB 1q23 chain A Region: 1 - 77 Aligned: 69 Modelled: 77 Confidence: 99.7% Identity: 7% Fold: CoA-dependent acyltransferases Superfamily: CoA-dependent acyltransferases Family: CAT-like Phyre2 PDB 3cla chain A Region: 1 - 76 Aligned: 68 Modelled: 76 Confidence: 99.7% Identity: 15% Fold: CoA-dependent acyltransferases Superfamily: CoA-dependent acyltransferases Family: CAT-like Phyre2 PDB 2i9d chain C Region: 1 - 74 Aligned: 66 Modelled: 74 Confidence: 99.7% Identity: 20% PDB header:transferase Chain: C: PDB Molecule:chloramphenicol acetyltransferase; PDBTitle: chloramphenicol acetyltransferase Phyre2 PDB 2zba chain D Region: 46 - 74 Aligned: 29 Modelled: 29 Confidence: 80.5% Identity: 17% PDB header:transferase Chain: D: PDB Molecule:trichothecene 3-o-acetyltransferase; PDBTitle: crystal structure of f. sporotrichioides tri101 complexed with2 coenzyme a and t-2 Phyre2 PDB 2xt6 chain B Region: 24 - 74 Aligned: 41 Modelled: 51 Confidence: 78.8% Identity: 15% PDB header:lyase Chain: B: PDB Molecule:2-oxoglutarate decarboxylase; PDBTitle: crystal structure of mycobacterium smegmatis alpha-ketoglutarate2 decarboxylase homodimer (orthorhombic form) Phyre2 PDB 3fot chain A Region: 41 - 75 Aligned: 35 Modelled: 35 Confidence: 77.9% Identity: 9% PDB header:transferase Chain: A: PDB Molecule:15-o-acetyltransferase; PDBTitle: structural and functional characterization of tri3 trichothecene 15-o-2 acetyltransferase from fusarium sporotrichioides Phyre2 PDB 2e1u chain A Region: 46 - 74 Aligned: 29 Modelled: 29 Confidence: 75.8% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:acyl transferase; PDBTitle: crystal structure of dendranthema morifolium dmat Phyre2 PDB 4ke4 chain A Region: 46 - 74 Aligned: 29 Modelled: 29 Confidence: 74.5% Identity: 28% PDB header:transferase Chain: A: PDB Molecule:hydroxycinnamoyl-coa:shikimate hydroxycinnamoyl PDBTitle: elucidation of the structure and reaction mechanism of sorghum bicolor2 hydroxycinnamoyltransferase and its structural relationship to other3 coa-dependent transferases and synthases Phyre2 PDB 3b2s chain A Region: 46 - 74 Aligned: 29 Modelled: 29 Confidence: 72.5% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:trichothecene 3-o-acetyltransferase; PDBTitle: crystal structure of f. graminearum tri101 complexed with coenzyme a2 and deoxynivalenol Phyre2 PDB 4g0b chain A Region: 46 - 77 Aligned: 32 Modelled: 32 Confidence: 68.1% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:hydroxycinnamoyl-coa shikimate/quinate PDBTitle: structure of native hct from coffea canephora Phyre2 1 d1b5sa_ 2 c4n72B_ 3 c3l60A_ 4 d1dpba_ 5 c2ii4C_ 6 c3b8kA_ 7 d1scza_ 8 c3maeA_ 9 c6h60A_ 10 c3rqcB_ 11 d1q23a_ 12 d3claa_ 13 c2i9dC_ 14 c2zbaD_ 15 c2xt6B_ 16 c3fotA_ 17 c2e1uA_ 18 c4ke4A_ 19 c3b2sA_ 20 c4g0bA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96