1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		L	P	G	G	V	C	S	G	R	P	W	G	R	P	W	W	H	P	G	L	V	G	L	L	I	R	L	A	E	L	L	V	V	M	L	P	L	I	G	V	L	Y	V	G	I	K	A	L	S	S	F	T	R	R	L	G	E	A	S	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																																		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	L	A	S	D	S	P	A	M	P	R	P	T	T	V	E	N	D	A	A	R	W	R	A	I	T	R	A	V	E	A	H	E	R	T	D	A	R	W	L	E	Y	E	L	D	A	A	K	L	L	D	F	P	V	M	T	D	M	R	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	L	T	T	A	F	H	K	A	K	L	Q	A	D	F	H	K	P	L	R	A	E	D	L	L	D	D	P	D	A	A	G	H	Y	L	D	A	V	R	D	Y	V	T	A	F	D	T	A	E	A	E	A	M	R	R	R	R	T	G	F
Secondary structure
SS confidence
Disorder															?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																											?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	R	E	E	Q	Q	R	L	A	R	A	Q	S	L	L	R	V	A	S	D	A	G	A	T	A	Q	E	R	E	R	A	Y	R	L	A	R	T	E	L	D	G	L	I	V	L	P	D	R	T	R	A	G	I	E	R	G	I	A	G	E
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?															?	?					?															?
Disorder confidence
		.	.	.
Sequence		L	D	D
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 26%) Alpha helix ( 70%) Beta strand ( 0%) TM helix ( 11%) (View membrane topology prediction)

Rank Aligned region

PDB 6c6l chain N Region: 31 - 50 Aligned: 20 Modelled: 20 Confidence: 80.9% Identity: 30% PDB header:membrane protein Chain: N: PDB Molecule:v0 assembly protein 1; PDBTitle: yeast vacuolar atpase vo in lipid nanodisc Phyre2 PDB 2qn5 chain B Region: 2 - 12 Aligned: 11 Modelled: 11 Confidence: 19.4% Identity: 64% PDB header:hydrolase inhibitor/hydrolase Chain: B: PDB Molecule:bowman-birk type bran trypsin inhibitor; PDBTitle: crystal structure and functional study of the bowman-birk2 inhibitor from rice bran in complex with bovine trypsin Phyre2 PDB 5gan chain A Region: 3 - 231 Aligned: 167 Modelled: 192 Confidence: 19.2% Identity: 23% PDB header:transcription Chain: A: PDB Molecule:pre-mrna-splicing factor 8; PDBTitle: the overall structure of the yeast spliceosomal u4/u6.u5 tri-snrnp at2 3.7 angstrom Phyre2 PDB 3ktc chain B Region: 123 - 204 Aligned: 78 Modelled: 82 Confidence: 16.7% Identity: 10% PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_050048.1) from2 erwinia carotovora atroseptica scri1043 at 1.54 a resolution Phyre2 PDB 5doq chain C Region: 24 - 46 Aligned: 23 Modelled: 23 Confidence: 16.0% Identity: 39% PDB header:oxidoreductase Chain: C: PDB Molecule:putative membrane protein; PDBTitle: the structure of bd oxidase from geobacillus thermodenitrificans Phyre2 PDB 5ir6 chain C Region: 24 - 46 Aligned: 23 Modelled: 23 Confidence: 16.0% Identity: 39% PDB header:oxidoreductase Chain: C: PDB Molecule:putative membrane protein; PDBTitle: the structure of bd oxidase from geobacillus thermodenitrificans Phyre2 PDB 2mf3 chain A Region: 5 - 15 Aligned: 11 Modelled: 11 Confidence: 14.7% Identity: 55% PDB header:toxin Chain: A: PDB Molecule:u2-segestritoxin-sf1a; PDBTitle: sgtx-sf1a Phyre2 PDB 5ow2 chain A Region: 43 - 56 Aligned: 14 Modelled: 14 Confidence: 12.4% Identity: 57% PDB header:viral protein Chain: A: PDB Molecule:capsid protein; PDBTitle: japanese encephalitis virus capsid protein Phyre2 PDB 1ks9 chain A domain 1 Region: 12 - 50 Aligned: 39 Modelled: 39 Confidence: 12.2% Identity: 23% Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like Family: Ketopantoate reductase PanE Phyre2 PDB 4xu6 chain A Region: 11 - 22 Aligned: 12 Modelled: 12 Confidence: 12.1% Identity: 58% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of cross-linked mvins r77c trimer at 1.9a resolution Phyre2 PDB 3ez0 chain D Region: 29 - 98 Aligned: 65 Modelled: 65 Confidence: 10.7% Identity: 18% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:uncharacterized protein with ferritin-like fold; PDBTitle: crystal structure of protein of unknown function with ferritin-like2 fold (yp_832262.1) from arthrobacter sp. fb24 at 2.33 a resolution Phyre2 PDB 4uy8 chain 7 Region: 13 - 17 Aligned: 5 Modelled: 1 Confidence: 10.3% Identity: 80% PDB header:ribosome Chain: 7: PDB Molecule:tryptophanase; PDB Fragment:residues 7-85; PDBTitle: molecular basis for the ribosome functioning as a l-tryptophan sensor2 - cryo-em structure of a tnac stalled e.coli ribosome Phyre2 PDB 4b6a chain X Region: 104 - 117 Aligned: 14 Modelled: 14 Confidence: 9.1% Identity: 29% PDB header:ribosome Chain: X: PDB Molecule:60s ribosomal protein l25; PDBTitle: cryo-em structure of the 60s ribosomal subunit in complex2 with arx1 and rei1 Phyre2 PDB 3tuf chain A Region: 184 - 220 Aligned: 37 Modelled: 37 Confidence: 8.8% Identity: 27% PDB header:signaling protein Chain: A: PDB Molecule:stage iii sporulation protein ah; PDBTitle: structure of the spoiiq-spoiiiah pore forming complex. Phyre2 PDB 5wda chain L Region: 27 - 41 Aligned: 14 Modelled: 15 Confidence: 8.7% Identity: 50% PDB header:protein transport Chain: L: PDB Molecule:general secretion pathway protein g; PDBTitle: structure of the pulg pseudopilus Phyre2 PDB 1sfk chain A Region: 44 - 56 Aligned: 13 Modelled: 13 Confidence: 8.2% Identity: 46% Fold: Flavivirus capsid protein C Superfamily: Flavivirus capsid protein C Family: Flavivirus capsid protein C Phyre2 PDB 2pil chain A Region: 27 - 54 Aligned: 28 Modelled: 28 Confidence: 8.1% Identity: 29% Fold: Pili subunits Superfamily: Pili subunits Family: Pilin Phyre2 PDB 5lj3 chain F Region: 16 - 21 Aligned: 6 Modelled: 6 Confidence: 8.1% Identity: 50% PDB header:splicing Chain: F: PDB Molecule:pre-mrna-splicing factor cwc25; PDBTitle: structure of the core of the yeast spliceosome immediately after2 branching Phyre2 PDB 3uz0 chain A Region: 184 - 220 Aligned: 37 Modelled: 37 Confidence: 7.9% Identity: 27% PDB header:transport protein Chain: A: PDB Molecule:stage iii sporulation protein ah; PDBTitle: crystal structure of spoiiiah and spoiiq complex Phyre2 PDB 2mi2 chain A Region: 25 - 60 Aligned: 34 Modelled: 36 Confidence: 7.8% Identity: 26% PDB header:transport protein Chain: A: PDB Molecule:sec-independent protein translocase protein tatb; PDBTitle: solution structure of the e. coli tatb protein in dpc micelles Phyre2 1 c6c6lN_ 2 c2qn5B_ 3 c5ganA_ 4 c3ktcB_ 5 c5doqC_ 6 c5ir6C_ 7 c2mf3A_ 8 c5ow2A_ 9 d1ks9a1 10 c4xu6A_ 11 c3ez0D_ 12 c4uy87_ 13 c4b6aX_ 14 c3tufA_ 15 c5wdaL_ 16 d1sfka_ 17 d2pila_ 18 c5lj3F_ 19 c3uz0A_ 20 c2mi2A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53