1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	L	R	A	V	N	E	I	R	Q	H	D	G	T	L	K	L	G	K	G	V	G	M	F	T	I	V	G	V	I	V	A	L	I	G	A	F	V	Q	S	R	R	H	R	H	R	P	A	A	D	I	H	M	L	W	W	M	V	L	I
Secondary structure
SS confidence
Disorder		?	?	?	?						?			?	?	?	?	?																								?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	G	V	V	S	I	I	G	A	G	Y	H	V	F	D	G	E	R	T	A	E	L	I	G	Y	T	R	G	D	G	G	F	Q	W	E	N	A	M	G	D	L	A	I	G	V	V	G	L	M	A	Y	R	F	R	G	H	F	W	L	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	I	V	V	L	T	I	Q	Y	V	G	D	A	A	G	H	I	Y	Y	W	V	V	E	N	N	T	N	P	Y	N	I	G	V	P	L	W	T	D	I	L	L	P	I	V	M	W	A	L	Y	A	W	S	W	H	S	N	G	D	A	V
Secondary structure
SS confidence
Disorder																																																								?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.
Sequence		P	K	G	Q	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 80%) Beta strand ( 0%) TM helix ( 49%) (View membrane topology prediction)

Rank Aligned region

PDB 1bcc chain C domain 3 Region: 54 - 183 Aligned: 119 Modelled: 130 Confidence: 30.2% Identity: 19% Fold: Heme-binding four-helical bundle Superfamily: Transmembrane di-heme cytochromes Family: Cytochrome b of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Phyre2 PDB 1ppj chain C domain 2 Region: 54 - 185 Aligned: 121 Modelled: 127 Confidence: 25.7% Identity: 17% Fold: Heme-binding four-helical bundle Superfamily: Transmembrane di-heme cytochromes Family: Cytochrome b of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Phyre2 PDB 4ojp chain C Region: 9 - 25 Aligned: 17 Modelled: 17 Confidence: 25.3% Identity: 41% PDB header:viral protein Chain: C: PDB Molecule:tailspike protein; PDBTitle: crystal structure of putative tailspike protein (tsp1, orf210) from2 escherichia coli o157:h7 bacteriohage cba120 in complex with maltose Phyre2 PDB 3cx5 chain C domain 2 Region: 101 - 183 Aligned: 82 Modelled: 83 Confidence: 25.2% Identity: 17% Fold: Heme-binding four-helical bundle Superfamily: Transmembrane di-heme cytochromes Family: Cytochrome b of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Phyre2 PDB 3cwb chain C Region: 54 - 185 Aligned: 121 Modelled: 127 Confidence: 20.0% Identity: 19% PDB header:oxidoreductase Chain: C: PDB Molecule:cytochrome b; PDBTitle: chicken cytochrome bc1 complex inhibited by an iodinated analogue of2 the polyketide crocacin-d Phyre2 PDB 4uis chain B Region: 29 - 119 Aligned: 82 Modelled: 28 Confidence: 18.8% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:gamma-secretase; PDBTitle: the cryoem structure of human gamma-secretase complex Phyre2 PDB 2qjk chain M Region: 101 - 183 Aligned: 82 Modelled: 83 Confidence: 14.6% Identity: 26% PDB header:electron transport Chain: M: PDB Molecule:cytochrome b; PDBTitle: crystal structure analysis of mutant rhodobacter2 sphaeroides bc1 with stigmatellin and antimycin Phyre2 PDB 3cx5 chain N Region: 101 - 183 Aligned: 82 Modelled: 83 Confidence: 14.5% Identity: 17% PDB header:oxidoreductase Chain: N: PDB Molecule:cytochrome b; PDBTitle: structure of complex iii with bound cytochrome c in reduced state and2 definition of a minimal core interface for electron transfer. Phyre2 PDB 5u1t chain B Region: 74 - 95 Aligned: 19 Modelled: 22 Confidence: 14.2% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:securin; PDBTitle: crystal structure of the saccharomyces cerevisiae separase-securin2 complex at 2.6 angstrom resolution Phyre2 PDB 5fsg chain A Region: 138 - 185 Aligned: 48 Modelled: 48 Confidence: 14.0% Identity: 19% PDB header:viral protein Chain: A: PDB Molecule:maltose-binding periplasmic protein, hantavirus PDBTitle: structure of the hantavirus nucleoprotein provides insights2 into the mechanism of rna encapsidation and a template for3 drug design Phyre2 PDB 6g7o chain A Region: 26 - 67 Aligned: 39 Modelled: 42 Confidence: 12.7% Identity: 18% PDB header:membrane protein Chain: A: PDB Molecule:alkaline ceramidase 3,soluble cytochrome b562; PDBTitle: crystal structure of human alkaline ceramidase 3 (acer3) at 2.72 angstrom resolution Phyre2 PDB 1e57 chain A Region: 91 - 97 Aligned: 7 Modelled: 7 Confidence: 11.2% Identity: 43% Fold: Nucleoplasmin-like/VP (viral coat and capsid proteins) Superfamily: Positive stranded ssRNA viruses Family: Tymoviridae-like VP Phyre2 PDB 1mrz chain A domain 1 Region: 81 - 89 Aligned: 9 Modelled: 9 Confidence: 11.2% Identity: 22% Fold: Reductase/isomerase/elongation factor common domain Superfamily: Riboflavin kinase-like Family: ATP-dependent riboflavin kinase-like Phyre2 PDB 1jek chain B Region: 6 - 17 Aligned: 12 Modelled: 12 Confidence: 11.0% Identity: 58% PDB header:viral protein Chain: B: PDB Molecule:env polyprotein; PDBTitle: visna tm core structure Phyre2 PDB 1nek chain B domain 2 Region: 1 - 15 Aligned: 15 Modelled: 15 Confidence: 10.7% Identity: 27% Fold: beta-Grasp (ubiquitin-like) Superfamily: 2Fe-2S ferredoxin-like Family: 2Fe-2S ferredoxin domains from multidomain proteins Phyre2 PDB 1ddl chain A Region: 91 - 97 Aligned: 7 Modelled: 7 Confidence: 9.6% Identity: 43% Fold: Nucleoplasmin-like/VP (viral coat and capsid proteins) Superfamily: Positive stranded ssRNA viruses Family: Tymoviridae-like VP Phyre2 PDB 6onq chain A Region: 136 - 185 Aligned: 48 Modelled: 50 Confidence: 9.4% Identity: 17% PDB header:electron transport Chain: A: PDB Molecule:cytochrome c xoxg; PDBTitle: crystal structure of c-type cytochrome xoxg from methylobacterium2 extorquens am1 Phyre2 PDB 2hkj chain A domain 2 Region: 88 - 99 Aligned: 11 Modelled: 12 Confidence: 8.8% Identity: 27% Fold: Ribosomal protein S5 domain 2-like Superfamily: Ribosomal protein S5 domain 2-like Family: DNA gyrase/MutL, second domain Phyre2 PDB 1auy chain A Region: 91 - 96 Aligned: 6 Modelled: 6 Confidence: 8.7% Identity: 50% Fold: Nucleoplasmin-like/VP (viral coat and capsid proteins) Superfamily: Positive stranded ssRNA viruses Family: Tymoviridae-like VP Phyre2 PDB 1e57 chain B Region: 91 - 97 Aligned: 7 Modelled: 7 Confidence: 8.5% Identity: 43% Fold: Nucleoplasmin-like/VP (viral coat and capsid proteins) Superfamily: Positive stranded ssRNA viruses Family: Tymoviridae-like VP Phyre2 1 d1bccc3 2 d1ppjc2 3 c4ojpC_ 4 d3cx5c2 5 c3cwbC_ 6 c4uisB_ 7 c2qjkM_ 8 c3cx5N_ 9 c5u1tB_ 10 c5fsgA_ 11 c6g7oA_ 12 d1e57a_ 13 d1mrza1 14 c1jekB_ 15 d1nekb2 16 d1ddla_ 17 c6onqA_ 18 d2hkja2 19 d1auya_ 20 d1e57b_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36