1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	A	G	C	Y	A	V	H	M	A	H	T	F	G	G	A	T	P	E	V	V	S	A	Q	A	K	L	R	D	P	A	V	D	R	A	M	T	A	E	L	K	F	P	G	G	H	T	G	G	I	R	C	S	M	R	S	S	D	L
Secondary structure
SS confidence
Disorder		?	?																																																							?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	N	V	S	A	R	V	V	G	D	R	G	E	L	R	V	L	N	P	V	V	P	Q	L	F	H	R	L	P	P	L	A	C	V	S	A	R	R	F	R	C	R	S	A	A	R	A	S	G	Q	D	D	A	Q	G	R	G	R	E	H
Secondary structure
SS confidence
Disorder		?																														?		?	?	?	?	?	?			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.
Sequence		E	R	D	P	R	D	L	S	G	R	R	A	P	I	A	Q	P	E	L	N	M	V	A	A	S	G	S	A	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?			?						?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 37%) Alpha helix ( 6%) Beta strand ( 45%)

Rank Aligned region

PDB 1ydw chain A domain 2 Region: 1 - 82 Aligned: 80 Modelled: 82 Confidence: 99.6% Identity: 33% Fold: FwdE/GAPDH domain-like Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family: Glucose 6-phosphate dehydrogenase-like Phyre2 PDB 3evn chain A Region: 1 - 112 Aligned: 110 Modelled: 112 Confidence: 99.5% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of putative oxidoreductase from streptococcus2 agalactiae 2603v/r Phyre2 PDB 3oqb chain F Region: 1 - 148 Aligned: 146 Modelled: 148 Confidence: 99.4% Identity: 13% PDB header:oxidoreductase Chain: F: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase from bradyrhizobium2 japonicum usda 110 Phyre2 PDB 3e9m chain C Region: 1 - 92 Aligned: 90 Modelled: 92 Confidence: 99.4% Identity: 18% PDB header:oxidoreductase Chain: C: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis Phyre2 PDB 1h6d chain A domain 2 Region: 1 - 96 Aligned: 94 Modelled: 96 Confidence: 99.4% Identity: 19% Fold: FwdE/GAPDH domain-like Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family: Glucose 6-phosphate dehydrogenase-like Phyre2 PDB 4miy chain B Region: 1 - 145 Aligned: 136 Modelled: 145 Confidence: 99.4% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase; PDBTitle: crystal structure of myo-inositol dehydrogenase from lactobacillus2 casei in complex with nad and myo-inositol Phyre2 PDB 1zh8 chain A domain 2 Region: 1 - 89 Aligned: 86 Modelled: 89 Confidence: 99.3% Identity: 21% Fold: FwdE/GAPDH domain-like Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family: Glucose 6-phosphate dehydrogenase-like Phyre2 PDB 2o48 chain X Region: 1 - 129 Aligned: 123 Modelled: 129 Confidence: 99.3% Identity: 25% PDB header:oxidoreductase Chain: X: PDB Molecule:dimeric dihydrodiol dehydrogenase; PDBTitle: crystal structure of mammalian dimeric dihydrodiol dehydrogenase Phyre2 PDB 2glx chain D Region: 1 - 144 Aligned: 134 Modelled: 144 Confidence: 99.3% Identity: 13% PDB header:oxidoreductase Chain: D: PDB Molecule:1,5-anhydro-d-fructose reductase; PDBTitle: crystal structure analysis of bacterial 1,5-af reductase Phyre2 PDB 2nvw chain A domain 2 Region: 1 - 100 Aligned: 100 Modelled: 100 Confidence: 99.3% Identity: 7% Fold: FwdE/GAPDH domain-like Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family: Glucose 6-phosphate dehydrogenase-like Phyre2 PDB 3ezy chain B Region: 1 - 100 Aligned: 100 Modelled: 100 Confidence: 99.3% Identity: 19% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:dehydrogenase; PDBTitle: crystal structure of probable dehydrogenase tm_0414 from thermotoga2 maritima Phyre2 PDB 4mkz chain A Region: 1 - 144 Aligned: 137 Modelled: 144 Confidence: 99.3% Identity: 13% PDB header:oxidoreductase Chain: A: PDB Molecule:inositol dehydrogenase; PDBTitle: crystal structure of apo scyllo-inositol dehydrogenase from2 lactobacillus casei at 77k Phyre2 PDB 6nor chain B Region: 1 - 141 Aligned: 140 Modelled: 141 Confidence: 99.3% Identity: 12% PDB header:oxidoreductase Chain: B: PDB Molecule:putative nad dependent dehydrogenase; PDBTitle: crystal structure of gend2 from gentamicin a biosynthesis in complex2 with nad Phyre2 PDB 2p2s chain A Region: 1 - 144 Aligned: 136 Modelled: 136 Confidence: 99.2% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase (yp_050235.1) from2 erwinia carotovora atroseptica scri1043 at 1.25 a resolution Phyre2 PDB 3e18 chain A Region: 1 - 144 Aligned: 143 Modelled: 144 Confidence: 99.2% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of nad-binding protein from listeria innocua Phyre2 PDB 3q2k chain B Region: 1 - 104 Aligned: 103 Modelled: 104 Confidence: 99.2% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of the wlba dehydrogenase from bordetella pertussis2 in complex with nadh and udp-glcnaca Phyre2 PDB 3rbv chain A Region: 1 - 83 Aligned: 81 Modelled: 83 Confidence: 99.2% Identity: 25% PDB header:sugar binding protein Chain: A: PDB Molecule:sugar 3-ketoreductase; PDBTitle: crystal structure of kijd10, a 3-ketoreductase from actinomadura2 kijaniata incomplex with nadp Phyre2 PDB 3nt5 chain B Region: 1 - 85 Aligned: 85 Modelled: 85 Confidence: 99.2% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase; PDBTitle: crystal structure of myo-inositol dehydrogenase from bacillus subtilis2 with bound cofactor and product inosose Phyre2 PDB 3dty chain A Region: 1 - 92 Aligned: 92 Modelled: 92 Confidence: 99.2% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of an oxidoreductase from pseudomonas2 syringae Phyre2 PDB 2nvw chain B Region: 1 - 96 Aligned: 96 Modelled: 96 Confidence: 99.2% Identity: 9% PDB header:transcription Chain: B: PDB Molecule:galactose/lactose metabolism regulatory protein PDBTitle: crystal sctucture of transcriptional regulator gal80p from2 kluyveromymes lactis Phyre2 1 d1ydwa2 2 c3evnA_ 3 c3oqbF_ 4 c3e9mC_ 5 d1h6da2 6 c4miyB_ 7 d1zh8a2 8 c2o48X_ 9 c2glxD_ 10 d2nvwa2 11 c3ezyB_ 12 c4mkzA_ 13 c6norB_ 14 c2p2sA_ 15 c3e18A_ 16 c3q2kB_ 17 c3rbvA_ 18 c3nt5B_ 19 c3dtyA_ 20 c2nvwB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85