1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		L	G	S	T	G	G	S	Q	P	M	T	A	N	R	G	P	A	A	I	S	S	G	S	N	S	G	R	V	L	D	T	A	R	G	I	L	I	A	L	R	R	C	P	A	E	T	A	F	D	E	L	H	N	A	A	Q	R	H	R	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.
Sequence		P	V	F	E	I	A	W	A	L	V	H	L	A	V	E	G	S	T	P	C	R	S	F	V	D	A	Q	S	A	A	R	R	E	W	G	Q	L	F	A	H	A	A	A
Secondary structure
SS confidence
Disorder																		?		?	?	?	?	?	?	?	?													?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 36%) Alpha helix ( 66%) Beta strand ( 0%)

Rank Aligned region

PDB 4akk chain A Region: 13 - 74 Aligned: 62 Modelled: 62 Confidence: 99.5% Identity: 19% PDB header:transcription Chain: A: PDB Molecule:nitrate regulatory protein; PDBTitle: structure of the nasr transcription antiterminator Phyre2 PDB 1qo0 chain D Region: 12 - 70 Aligned: 59 Modelled: 59 Confidence: 98.7% Identity: 17% Fold: Flavodoxin-like Superfamily: CheY-like Family: Positive regulator of the amidase operon AmiR Phyre2 PDB 1s8n chain A Region: 19 - 74 Aligned: 56 Modelled: 56 Confidence: 97.4% Identity: 18% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 4mc8 chain A Region: 32 - 94 Aligned: 63 Modelled: 63 Confidence: 82.5% Identity: 19% PDB header:lyase Chain: A: PDB Molecule:putative sesquiterpene cyclase; PDBTitle: hedycaryol synthase in complex with hepes Phyre2 PDB 4bba chain A Region: 25 - 71 Aligned: 47 Modelled: 47 Confidence: 82.0% Identity: 13% PDB header:protein-binding protein Chain: A: PDB Molecule:glucokinase regulatory protein; PDBTitle: crystal structure of glucokinase regulatory protein complexed to2 phosphate Phyre2 PDB 1ps1 chain A Region: 35 - 101 Aligned: 67 Modelled: 67 Confidence: 78.9% Identity: 6% Fold: Terpenoid synthases Superfamily: Terpenoid synthases Family: Aristolochene/pentalenene synthase Phyre2 PDB 1di1 chain A Region: 35 - 78 Aligned: 44 Modelled: 44 Confidence: 78.5% Identity: 11% Fold: Terpenoid synthases Superfamily: Terpenoid synthases Family: Aristolochene/pentalenene synthase Phyre2 PDB 3w0l chain D Region: 25 - 51 Aligned: 27 Modelled: 27 Confidence: 77.1% Identity: 15% PDB header:transferase/transferase inhibitor Chain: D: PDB Molecule:glucokinase regulatory protein; PDBTitle: the crystal structure of xenopus glucokinase and glucokinase2 regulatory protein complex Phyre2 PDB 6q4s chain A Region: 32 - 94 Aligned: 63 Modelled: 63 Confidence: 75.0% Identity: 16% PDB header:unknown function Chain: A: PDB Molecule:pentalenene synthase; PDBTitle: crystal structure of a-eudesmol synthase Phyre2 PDB 5nx6 chain A Region: 32 - 94 Aligned: 63 Modelled: 63 Confidence: 72.5% Identity: 11% PDB header:lyase Chain: A: PDB Molecule:pentalenene synthase; PDBTitle: crystal structure of 1,8-cineole synthase from streptomyces2 clavuligerus in complex with 2-fluoroneryl diphosphate Phyre2 PDB 5i1u chain B Region: 35 - 94 Aligned: 60 Modelled: 60 Confidence: 72.2% Identity: 20% PDB header:lyase Chain: B: PDB Molecule:germacradien-4-ol synthase; PDBTitle: crystal structure of germacradien-4-ol synthase from streptomyces2 citricolor Phyre2 PDB 4lc9 chain A Region: 25 - 65 Aligned: 41 Modelled: 41 Confidence: 70.3% Identity: 10% PDB header:transferase/transferase regulator Chain: A: PDB Molecule:glucokinase regulatory protein; PDBTitle: structural basis for regulation of human glucokinase by glucokinase2 regulatory protein Phyre2 PDB 3lg5 chain A Region: 32 - 74 Aligned: 43 Modelled: 43 Confidence: 69.1% Identity: 14% PDB header:lyase Chain: A: PDB Molecule:epi-isozizaene synthase; PDBTitle: f198a epi-isozizaene synthase: complex with mg, inorganic2 pyrophosphate and benzyl triethyl ammonium cation Phyre2 PDB 3v1v chain A Region: 35 - 72 Aligned: 38 Modelled: 38 Confidence: 68.2% Identity: 8% PDB header:lyase Chain: A: PDB Molecule:2-methylisoborneol synthase; PDBTitle: crystal structure of 2-methylisoborneol synthase from streptomyces2 coelicolor a3(2) in complex with mg2+ and geranyl-s-thiolodiphosphate Phyre2 PDB 5erm chain A Region: 32 - 69 Aligned: 38 Modelled: 38 Confidence: 67.1% Identity: 13% PDB header:lyase Chain: A: PDB Molecule:fusicoccadiene synthase; PDBTitle: crystal structure of cyclization domain of phomopsis amygdali2 fusicoccadiene synthase complexed with magnesium ions and pamidronate Phyre2 PDB 5dw7 chain A Region: 35 - 99 Aligned: 61 Modelled: 65 Confidence: 66.8% Identity: 13% PDB header:lyase Chain: A: PDB Molecule:germacradienol/geosmin synthase; PDBTitle: crystal structure of the unliganded geosmin synthase n-terminal domain2 from streptomyces coelicolor Phyre2 PDB 6egk chain B Region: 32 - 94 Aligned: 63 Modelled: 63 Confidence: 62.5% Identity: 8% PDB header:lyase Chain: B: PDB Molecule:cucumene synthase; PDBTitle: t181n cucumene synthase Phyre2 PDB 1tr8 chain A Region: 35 - 72 Aligned: 31 Modelled: 38 Confidence: 61.6% Identity: 19% PDB header:chaperone Chain: A: PDB Molecule:conserved protein (mth177); PDBTitle: crystal structure of archaeal nascent polypeptide-associated complex2 (aenac) Phyre2 PDB 4okm chain A Region: 32 - 71 Aligned: 40 Modelled: 40 Confidence: 60.2% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:terpene synthase metal-binding domain-containing protein; PDBTitle: selinadiene synthase apo and in complex with diphosphate Phyre2 PDB 2oa6 chain B Region: 32 - 69 Aligned: 38 Modelled: 38 Confidence: 58.3% Identity: 21% PDB header:lyase Chain: B: PDB Molecule:aristolochene synthase; PDBTitle: aristolochene synthase from aspergillus terreus complexed with2 pyrophosphate Phyre2 1 c4akkA_ 2 d1qo0d_ 3 d1s8na_ 4 c4mc8A_ 5 c4bbaA_ 6 d1ps1a_ 7 d1di1a_ 8 c3w0lD_ 9 c6q4sA_ 10 c5nx6A_ 11 c5i1uB_ 12 c4lc9A_ 13 c3lg5A_ 14 c3v1vA_ 15 c5ermA_ 16 c5dw7A_ 17 c6egkB_ 18 c1tr8A_ 19 c4okmA_ 20 c2oa6B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99