1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	S	D	L	Y	L	G	Y	R	N	D	D	A	D	T	P	F	G	K	F	F	K	P	E	M	A	P	L	P	Q	H	V	V	V	A	L	Q	H	G	P	Q	A	G	M	A	L	L	A	F	D	D	A	A	S	I	V	D	E	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?												?												?								?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Y	Q	Q	T	E	N	G	Y	G	I	L	G	D	G	S	M	Q	V	S	V	R	T	D	M	P	G	V	T	P	A	M	W	A	W	W	F	G	W	H	G	S	D	T	R	R	Y	K	L	W	H	P	R	A	H	L	S	A	R	W	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	G	D	Q	D	S	G	A	G	R	R	G	A	Q	R	Y	V	G	R	W	S	M	I	S	E	Y	I	G	S	T	K	L	G	A	A	I	Q	F	V	E	P	A	A	M	G	L	P	D	D	S	D	D	T	V	S	I	C	A	R	L
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?	?																																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	S	A	D	A	P	V	D	A	G	W	F	V	H	Q	V	R	S	T	P	G	G	S	E	M	R	S	R	F	W	M	G	G	P	H	I	A	V	R	K	A	P	E	V	A	S	K	A	V	R	P	I	A	S	K	L	I	G	V	S
Secondary structure
SS confidence
Disorder																																						?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.
Sequence		E	S	T	A	R	N	L	L	V	Y	C	A	Q	E	M	N	H	L	A	G	F	L	A	D	L	W	E	S	F	G	D	E
Secondary structure
SS confidence
Disorder																														?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 18%) Alpha helix ( 33%) Beta strand ( 22%)

Rank Aligned region

PDB 3hwp chain A Region: 10 - 270 Aligned: 260 Modelled: 260 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:phlg; PDBTitle: crystal structure and computational analyses provide insights into the2 catalytic mechanism of 2, 4-diacetylphloroglucinol hydrolase phlg3 from pseudomonas fluorescens Phyre2 PDB 5xey chain C Region: 11 - 268 Aligned: 234 Modelled: 240 Confidence: 100.0% Identity: 32% PDB header:hydrolase Chain: C: PDB Molecule:phloretin hydrolase; PDBTitle: discovery and structural analysis of a phloretin hydrolase from the2 opportunistic pathogen mycobacterium abscessus Phyre2 PDB 5zcr chain B Region: 11 - 116 Aligned: 99 Modelled: 106 Confidence: 62.9% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:maltooligosyl trehalose synthase; PDBTitle: dsm5389 glycosyltrehalose synthase Phyre2 PDB 2ciw chain A domain 2 Region: 92 - 111 Aligned: 20 Modelled: 20 Confidence: 44.7% Identity: 40% Fold: EF Hand-like Superfamily: Cloroperoxidase Family: Cloroperoxidase Phyre2 PDB 2w56 chain B Region: 22 - 84 Aligned: 63 Modelled: 63 Confidence: 27.1% Identity: 21% PDB header:unknown function Chain: B: PDB Molecule:vc0508; PDBTitle: structure of the hypothetical protein vc0508 from vibrio cholerae2 vsp-ii pathogenicity island Phyre2 PDB 6hu9 chain U Region: 94 - 99 Aligned: 6 Modelled: 6 Confidence: 20.2% Identity: 67% PDB header:oxidoreductase/electron transport Chain: U: PDB Molecule:cytochrome b-c1 complex subunit 10; PDBTitle: iii2-iv2 mitochondrial respiratory supercomplex from s. cerevisiae Phyre2 PDB 3hje chain A Region: 41 - 116 Aligned: 69 Modelled: 76 Confidence: 15.9% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:704aa long hypothetical glycosyltransferase; PDBTitle: crystal structure of sulfolobus tokodaii hypothetical maltooligosyl2 trehalose synthase Phyre2 PDB 3fwt chain A Region: 142 - 167 Aligned: 26 Modelled: 26 Confidence: 15.2% Identity: 12% PDB header:cytokine Chain: A: PDB Molecule:macrophage migration inhibitory factor-like PDBTitle: crystal structure of leishmania major mif2 Phyre2 PDB 2v1l chain A Region: 22 - 84 Aligned: 63 Modelled: 63 Confidence: 15.1% Identity: 21% PDB header:unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: structure of the conserved hypothetical protein vc1805 from2 pathogenicity island vpi-2 of vibrio cholerae o1 biovar3 eltor str. n16961 shares structural homology with the4 human p32 protein Phyre2 PDB 3b64 chain A Region: 142 - 167 Aligned: 26 Modelled: 26 Confidence: 14.2% Identity: 15% PDB header:cytokine Chain: A: PDB Molecule:macrophage migration inhibitory factor-like PDBTitle: macrophage migration inhibitory factor (mif) from2 /leishmania major Phyre2 PDB 6gu1 chain B Region: 237 - 269 Aligned: 33 Modelled: 33 Confidence: 11.5% Identity: 21% PDB header:unknown function Chain: B: PDB Molecule:secreted rxlr effector peptide protein, putative; PDBTitle: sfi3 effector protein from the oomycete plant pathogen phytophthora2 infestans Phyre2 PDB 2bw3 chain A domain 1 Region: 255 - 272 Aligned: 18 Modelled: 18 Confidence: 10.5% Identity: 11% Fold: Hermes dimerisation domain Superfamily: Hermes dimerisation domain Family: Hermes dimerisation domain Phyre2 PDB 5lnk chain U Region: 94 - 137 Aligned: 33 Modelled: 44 Confidence: 10.2% Identity: 21% PDB header:oxidoreductase Chain: U: PDB Molecule: PDBTitle: entire ovine respiratory complex i Phyre2 PDB 5m30 chain A Region: 54 - 77 Aligned: 24 Modelled: 24 Confidence: 9.9% Identity: 13% PDB header:secretion system Chain: A: PDB Molecule:type vi secretion protein; PDBTitle: structure of tssk from t6ss eaec in complex with nanobody nb18 Phyre2 PDB 5m30 chain B Region: 55 - 77 Aligned: 23 Modelled: 23 Confidence: 9.9% Identity: 13% PDB header:secretion system Chain: B: PDB Molecule:type vi secretion protein; PDBTitle: structure of tssk from t6ss eaec in complex with nanobody nb18 Phyre2 PDB 1wig chain A domain 2 Region: 108 - 127 Aligned: 20 Modelled: 20 Confidence: 9.2% Identity: 40% Fold: Glucocorticoid receptor-like (DNA-binding domain) Superfamily: Glucocorticoid receptor-like (DNA-binding domain) Family: LIM domain Phyre2 PDB 5m30 chain C Region: 55 - 77 Aligned: 23 Modelled: 23 Confidence: 8.5% Identity: 13% PDB header:secretion system Chain: C: PDB Molecule:type vi secretion protein; PDBTitle: structure of tssk from t6ss eaec in complex with nanobody nb18 Phyre2 PDB 6cp8 chain B Region: 68 - 82 Aligned: 15 Modelled: 15 Confidence: 8.2% Identity: 40% PDB header:toxin/antitoxin Chain: B: PDB Molecule:cdia; PDBTitle: contact-dependent growth inhibition toxin-immunity protein complex2 from from e. coli 3006 Phyre2 PDB 3wx4 chain A Region: 255 - 266 Aligned: 12 Modelled: 12 Confidence: 8.1% Identity: 33% PDB header:viral protein Chain: A: PDB Molecule:anti-restriction endonuclease; PDBTitle: crystal structure of t4 phage arn protein Phyre2 PDB 4bed chain D Region: 69 - 85 Aligned: 17 Modelled: 17 Confidence: 7.7% Identity: 18% PDB header:oxygen transport Chain: D: PDB Molecule:hemocyanin klh1; PDBTitle: keyhole limpet hemocyanin (klh): 9a cryoem structure and molecular2 model of the klh1 didecamer reveal the interfaces and intricate3 topology of the 160 functional units Phyre2 1 c3hwpA_ 2 c5xeyC_ 3 c5zcrB_ 4 d2ciwa2 5 c2w56B_ 6 c6hu9u_ 7 c3hjeA_ 8 c3fwtA_ 9 c2v1lA_ 10 c3b64A_ 11 c6gu1B_ 12 d2bw3a1 13 c5lnku_ 14 c5m30A_ 15 c5m30B_ 16 d1wiga2 17 c5m30C_ 18 c6cp8B_ 19 c3wx4A_ 20 c4bedD_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45