1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	N	H	D	Y	V	T	Y	E	E	F	G	R	R	F	F	E	V	A	V	T	P	D	R	V	A	A	A	F	A	D	I	A	G	S	E	F	A	M	E	P	I	S	Q	G	P	G	G	I	A	K	V	S	A	N	V	K	I	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																										?	?	?	?									?	?	?	?	?									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	P	R	V	T	R	K	L	G	D	L	I	T	F	V	I	H	I	P	L	S	I	D	L	L	L	D	L	R	L	D	K	Q	R	F	M	V	A	G	D	I	A	L	R	A	T	A	R	A	A	E	P	L	L	L	I	V	D	V	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?																							?		?	?	?	?	?	?	?	?							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		K	P	R	P	S	D	I	T	V	N	V	S	S	K	S	I	R	G	E	V	L	R	I	L	A	G	V	D	G	E	I	R	R	F	I	A	Q	Y	V	S	A	E	I	D	S	P	K	S	Q	A	A	Q	V	I	N	V	A	E	Q	L
Secondary structure
SS confidence
Disorder			?	?	?									?	?		?										?																	?	?	?	?	?	?	?	?	?		?	?						?
Disorder confidence
		.	.	.	.	.	.	.
Sequence		D	S	T	W	S	G	P
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 33%) Alpha helix ( 36%) Beta strand ( 40%)

Rank Aligned region

PDB 5mww chain A Region: 6 - 40 Aligned: 35 Modelled: 35 Confidence: 39.3% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:rna polymerase sigma factor siga; PDBTitle: sigma1.1 domain of sigmaa from bacillus subtilis Phyre2 PDB 2v3s chain B Region: 113 - 183 Aligned: 68 Modelled: 71 Confidence: 36.8% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase osr1; PDBTitle: structural insights into the recognition of substrates and2 activators by the osr1 kinase Phyre2 PDB 1zmb chain A domain 1 Region: 3 - 20 Aligned: 18 Modelled: 18 Confidence: 32.7% Identity: 33% Fold: Flavodoxin-like Superfamily: SGNH hydrolase Family: Putative acetylxylan esterase-like Phyre2 PDB 2k6x chain A Region: 6 - 40 Aligned: 35 Modelled: 35 Confidence: 22.2% Identity: 14% PDB header:transcription Chain: A: PDB Molecule:rna polymerase sigma factor rpod; PDBTitle: autoregulation of a group 1 bacterial sigma factor involves2 the formation of a region 1.1- induced compacted structure Phyre2 PDB 2idc chain A Region: 36 - 78 Aligned: 37 Modelled: 38 Confidence: 15.7% Identity: 14% PDB header:replication/chaperone Chain: A: PDB Molecule:anti-silencing protein 1 and histone h3 chimera; PDBTitle: structure of the histone h3-asf1 chaperone interaction Phyre2 PDB 6a6y chain A Region: 36 - 78 Aligned: 37 Modelled: 43 Confidence: 15.4% Identity: 19% PDB header:chaperone Chain: A: PDB Molecule:histone chaperone asf1, putative; PDBTitle: crystal structure of asf1 from plasmodium falciparum Phyre2 PDB 2i32 chain A domain 1 Region: 36 - 78 Aligned: 37 Modelled: 43 Confidence: 15.1% Identity: 14% Fold: Immunoglobulin-like beta-sandwich Superfamily: ASF1-like Family: ASF1-like Phyre2 PDB 2i32 chain A Region: 36 - 78 Aligned: 37 Modelled: 43 Confidence: 15.1% Identity: 14% PDB header:replication chaperone Chain: A: PDB Molecule:anti-silencing factor 1 paralog a; PDBTitle: structure of a human asf1a-hira complex and insights into specificity2 of histone chaperone complex assembly Phyre2 PDB 1roc chain A Region: 36 - 78 Aligned: 37 Modelled: 43 Confidence: 14.5% Identity: 14% Fold: Immunoglobulin-like beta-sandwich Superfamily: ASF1-like Family: ASF1-like Phyre2 PDB 3zpm chain A Region: 73 - 163 Aligned: 89 Modelled: 91 Confidence: 13.6% Identity: 18% PDB header:surfactant protein Chain: A: PDB Molecule:latherin; PDBTitle: solution structure of latherin Phyre2 PDB 3jb9 chain E Region: 41 - 51 Aligned: 11 Modelled: 11 Confidence: 13.4% Identity: 45% PDB header:rna binding protein/rna Chain: E: PDB Molecule:small nuclear ribonucleoprotein-associated protein b; PDBTitle: cryo-em structure of the yeast spliceosome at 3.6 angstrom resolution Phyre2 PDB 5fmn chain B Region: 130 - 152 Aligned: 23 Modelled: 23 Confidence: 11.3% Identity: 26% PDB header:dna binding protein Chain: B: PDB Molecule:inrs; PDBTitle: the nickel-responsive transcriptional regulator inrs Phyre2 PDB 3voq chain A Region: 32 - 54 Aligned: 16 Modelled: 23 Confidence: 10.1% Identity: 25% PDB header:membrane protein Chain: A: PDB Molecule:target of rapamycin complex 2 subunit mapkap1; PDBTitle: crystal structure of the pleckstrin homology domain of human sin1, a2 torc2 subunit Phyre2 PDB 5xtd chain K Region: 1 - 9 Aligned: 9 Modelled: 9 Confidence: 9.9% Identity: 67% PDB header:oxidoreductase/electron transport Chain: K: PDB Molecule:nadh dehydrogenase [ubiquinone] flavoprotein 3, PDBTitle: cryo-em structure of human respiratory complex i Phyre2 PDB 1u3u chain A domain 1 Region: 108 - 146 Aligned: 39 Modelled: 39 Confidence: 9.6% Identity: 18% Fold: GroES-like Superfamily: GroES-like Family: Alcohol dehydrogenase-like, N-terminal domain Phyre2 PDB 5lcy chain D Region: 132 - 152 Aligned: 21 Modelled: 21 Confidence: 8.2% Identity: 14% PDB header:transcription Chain: D: PDB Molecule:frmr; PDBTitle: formaldehyde-responsive regulator frmr e64h variant from salmonella2 enterica serovar typhimurium Phyre2 PDB 5lbm chain D Region: 132 - 152 Aligned: 21 Modelled: 21 Confidence: 7.4% Identity: 24% PDB header:transcription Chain: D: PDB Molecule:transcriptional repressor frmr; PDBTitle: the asymmetric tetrameric structure of the formaldehyde sensing2 transcriptional repressor frmr from escherichia coli Phyre2 PDB 2y69 chain S Region: 17 - 48 Aligned: 31 Modelled: 32 Confidence: 7.3% Identity: 19% PDB header:electron transport Chain: S: PDB Molecule:cytochrome c oxidase subunit 5b; PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular oxygen Phyre2 PDB 2dyj chain A domain 1 Region: 145 - 176 Aligned: 31 Modelled: 32 Confidence: 6.9% Identity: 19% Fold: Alpha-lytic protease prodomain-like Superfamily: Ribosome-binding factor A, RbfA Family: Ribosome-binding factor A, RbfA Phyre2 PDB 1u3w chain A domain 1 Region: 117 - 146 Aligned: 30 Modelled: 30 Confidence: 6.6% Identity: 20% Fold: GroES-like Superfamily: GroES-like Family: Alcohol dehydrogenase-like, N-terminal domain Phyre2 1 c5mwwA_ 2 c2v3sB_ 3 d1zmba1 4 c2k6xA_ 5 c2idcA_ 6 c6a6yA_ 7 d2i32a1 8 c2i32A_ 9 d1roca_ 10 c3zpmA_ 11 c3jb9E_ 12 c5fmnB_ 13 c3voqA_ 14 c5xtdK_ 15 d1u3ua1 16 c5lcyD_ 17 c5lbmD_ 18 c2y69S_ 19 d2dyja1 20 d1u3wa1 21 22 23 24 25 26 27