1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	V	V	S	T	L	L	S	I	P	L	M	I	G	L	A	V	P	A	H	A	G	P	S	G	D	D	A	V	F	L	A	S	L	E	R	A	G	I	T	Y	S	H	P	D	Q	A	I	A	S	G	K	A	V	C	A	L	V	E
Secondary structure
SS confidence
Disorder		?																			?		?	?	?	?	?	?											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.
Sequence		S	G	E	S	G	L	Q	V	V	N	E	L	R	T	R	N	P	G	F	S	M	D	G	C	C	K	F	A	A	I	S	A	H	V	Y	C	P	H	Q	I	T	K	T	S	V	S	A	K
Secondary structure
SS confidence
Disorder		?			?										?	?		?	?	?																						?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 22%) Alpha helix ( 67%) Beta strand ( 0%)

Rank Aligned region

PDB 6c3r chain B Region: 69 - 105 Aligned: 37 Modelled: 37 Confidence: 61.7% Identity: 14% PDB header:viral protein Chain: B: PDB Molecule:cricket paralysis virus 1a protein; PDBTitle: cricket paralysis virus rnai suppressor protein crpv-1a Phyre2 PDB 4rl6 chain A Region: 15 - 42 Aligned: 24 Modelled: 28 Confidence: 22.3% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: crystal structure of the q04l03_strp2 protein from streptococcus2 pneumoniae. northeast structural genomics consortium target spr105 Phyre2 PDB 3pvs chain A Region: 31 - 95 Aligned: 61 Modelled: 65 Confidence: 21.3% Identity: 16% PDB header:recombination Chain: A: PDB Molecule:replication-associated recombination protein a; PDBTitle: structure and biochemical activities of escherichia coli mgsa Phyre2 PDB 2csu chain A domain 3 Region: 24 - 51 Aligned: 28 Modelled: 28 Confidence: 20.4% Identity: 25% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 PDB 1mke chain A domain 1 Region: 39 - 61 Aligned: 23 Modelled: 23 Confidence: 15.0% Identity: 22% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 4ina chain A Region: 15 - 42 Aligned: 24 Modelled: 28 Confidence: 14.5% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: crystal structure of the q7mss8_wolsu protein from wolinella2 succinogenes. northeast structural genomics consortium target wsr35 Phyre2 PDB 5k9x chain A Region: 30 - 74 Aligned: 43 Modelled: 41 Confidence: 14.2% Identity: 21% PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of tryptophan synthase alpha chain from legionella2 pneumophila subsp. pneumophila Phyre2 PDB 2ekc chain A Region: 39 - 74 Aligned: 34 Modelled: 36 Confidence: 13.3% Identity: 21% PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 Phyre2 PDB 5uqd chain A Region: 28 - 43 Aligned: 16 Modelled: 16 Confidence: 11.8% Identity: 38% PDB header:oxidoreductase Chain: A: PDB Molecule:dumpy: shorter than wild-type; PDBTitle: dpy-21 in complex with fe(ii) and alpha-ketoglutarate Phyre2 PDB 5kin chain C Region: 23 - 80 Aligned: 56 Modelled: 58 Confidence: 10.5% Identity: 20% PDB header:lyase Chain: C: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of tryptophan synthase alpha beta complex from2 streptococcus pneumoniae Phyre2 PDB 2lwe chain A Region: 29 - 43 Aligned: 15 Modelled: 15 Confidence: 9.5% Identity: 20% PDB header:signaling protein Chain: A: PDB Molecule:probable atp-dependent rna helicase ddx58; PDBTitle: solution structure of mutant (t170e) second card of human rig-i Phyre2 PDB 3j9x chain J Region: 33 - 72 Aligned: 40 Modelled: 40 Confidence: 9.0% Identity: 28% PDB header:virus Chain: J: PDB Molecule:coat protein; PDBTitle: a virus that infects a hyperthermophile encapsidates a-form dna Phyre2 PDB 5tch chain G Region: 39 - 74 Aligned: 34 Modelled: 36 Confidence: 9.0% Identity: 24% PDB header:lyase Chain: G: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of tryptophan synthase from m. tuberculosis -2 ligand-free form, trpa-g66v mutant Phyre2 PDB 5l78 chain A Region: 2 - 42 Aligned: 38 Modelled: 41 Confidence: 8.9% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:alpha-aminoadipic semialdehyde synthase, mitochondrial; PDBTitle: crystal structure of human aminoadipate semialdehyde synthase,2 saccharopine dehydrogenase domain (in nad+ bound form) Phyre2 PDB 3ss4 chain C Region: 30 - 45 Aligned: 16 Modelled: 16 Confidence: 8.5% Identity: 31% PDB header:hydrolase Chain: C: PDB Molecule:glutaminase c; PDBTitle: crystal structure of mouse glutaminase c, phosphate-bound form Phyre2 PDB 2j9g chain A domain 2 Region: 26 - 52 Aligned: 27 Modelled: 27 Confidence: 8.3% Identity: 22% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: BC N-terminal domain-like Phyre2 PDB 1zsq chain A domain 2 Region: 24 - 64 Aligned: 40 Modelled: 41 Confidence: 7.8% Identity: 25% Fold: (Phosphotyrosine protein) phosphatases II Superfamily: (Phosphotyrosine protein) phosphatases II Family: Myotubularin-like phosphatases Phyre2 PDB 1ulz chain A domain 2 Region: 26 - 52 Aligned: 27 Modelled: 27 Confidence: 7.7% Identity: 33% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: BC N-terminal domain-like Phyre2 PDB 2mul chain A Region: 24 - 35 Aligned: 12 Modelled: 12 Confidence: 7.1% Identity: 58% PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase huwe1; PDBTitle: solution structure of the ubm1 domain of human huwe1/arf-bp1 Phyre2 PDB 3f2e chain A Region: 29 - 72 Aligned: 44 Modelled: 44 Confidence: 6.6% Identity: 23% PDB header:viral protein Chain: A: PDB Molecule:sirv coat protein; PDBTitle: crystal structure of yellowstone sirv coat protein c-terminus Phyre2 1 c6c3rB_ 2 c4rl6A_ 3 c3pvsA_ 4 d2csua3 5 d1mkea1 6 c4inaA_ 7 c5k9xA_ 8 c2ekcA_ 9 c5uqdA_ 10 c5kinC_ 11 c2lweA_ 12 c3j9xJ_ 13 c5tchG_ 14 c5l78A_ 15 c3ss4C_ 16 d2j9ga2 17 d1zsqa2 18 d1ulza2 19 c2mulA_ 20 c3f2eA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34