1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	V	R	L	V	P	R	A	F	A	A	T	V	A	L	L	A	A	G	F	S	P	A	T	A	S	A	D	P	V	L	V	F	P	G	M	E	I	R	Q	D	N	H	V	C	T	L	G	Y	V	D	P	A	L	K	I	A	F	T	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?				?	?	?	?	?	?		?	?	?	?	?	?	?	?												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	H	C	R	G	G	G	A	V	T	S	R	D	Y	K	V	I	G	H	L	R	A	F	R	D	N	T	P	S	G	S	T	V	A	T	H	E	L	I	A	D	Y	E	A	I	V	L	A	D	D	V	T	A	S	N	I	L	P	S	G
Secondary structure
SS confidence
Disorder												?												?	?	?	?	?		?		?			?																			?	?		?		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	A	L	E	S	R	P	G	V	V	L	H	P	G	Q	A	V	C	H	F	G	V	S	T	G	E	T	C	G	T	V	E	S	V	N	N	G	W	F	T	M	S	H	G	V	L	S	E	K	G	D	S	G	G	P	V	Y	L	A	P
Secondary structure
SS confidence
Disorder		?	?		?	?	?	?	?	?	?	?								?																												?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.
Sequence		D	G	G	P	A	Q	I	V	G	I	F	N	S	V	W	G	G	F	P	A	A	V	S	W	R	S	T	S	E	Q	V	H	A	D	L	G	V	T	P	L	A
Secondary structure
SS confidence
Disorder																	?																			?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 27%) Alpha helix ( 12%) Beta strand ( 47%)

Rank Aligned region

PDB 5mrt chain A Region: 31 - 221 Aligned: 175 Modelled: 191 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:lytic endopeptidase preproenzyme; PDBTitle: crystal structure of l5 protease lysobacter sp. xl1 Phyre2 PDB 2h5c chain A domain 1 Region: 32 - 220 Aligned: 173 Modelled: 189 Confidence: 100.0% Identity: 24% Fold: Trypsin-like serine proteases Superfamily: Trypsin-like serine proteases Family: Prokaryotic proteases Phyre2 PDB 2pfe chain A Region: 31 - 221 Aligned: 171 Modelled: 176 Confidence: 99.9% Identity: 24% PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:alkaline serine protease; PDBTitle: crystal structure of thermobifida fusca protease a (tfpa) Phyre2 PDB 2sga chain A Region: 32 - 220 Aligned: 167 Modelled: 172 Confidence: 99.9% Identity: 26% Fold: Trypsin-like serine proteases Superfamily: Trypsin-like serine proteases Family: Prokaryotic proteases Phyre2 PDB 2qaa chain A domain 1 Region: 32 - 218 Aligned: 171 Modelled: 187 Confidence: 99.9% Identity: 23% Fold: Trypsin-like serine proteases Superfamily: Trypsin-like serine proteases Family: Prokaryotic proteases Phyre2 PDB 2oua chain A Region: 32 - 218 Aligned: 168 Modelled: 174 Confidence: 99.9% Identity: 22% PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:serine protease; PDBTitle: crystal structure of nocardiopsis protease (napase) Phyre2 PDB 1hpg chain A Region: 32 - 218 Aligned: 172 Modelled: 187 Confidence: 99.9% Identity: 27% Fold: Trypsin-like serine proteases Superfamily: Trypsin-like serine proteases Family: Prokaryotic proteases Phyre2 PDB 2ea3 chain A Region: 31 - 220 Aligned: 168 Modelled: 173 Confidence: 99.9% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:chymotrypsin; PDBTitle: crystal structure of cellulomonas bogoriensis chymotrypsin Phyre2 PDB 2sfa chain A Region: 32 - 218 Aligned: 173 Modelled: 187 Confidence: 99.9% Identity: 24% Fold: Trypsin-like serine proteases Superfamily: Trypsin-like serine proteases Family: Prokaryotic proteases Phyre2 PDB 1agj chain A Region: 35 - 214 Aligned: 174 Modelled: 180 Confidence: 99.3% Identity: 13% Fold: Trypsin-like serine proteases Superfamily: Trypsin-like serine proteases Family: Prokaryotic proteases Phyre2 PDB 4ink chain A Region: 48 - 215 Aligned: 161 Modelled: 168 Confidence: 99.1% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:serine protease spld; PDBTitle: crystal structure of spld protease from staphylococcus aureus at 1.562 a resolution Phyre2 PDB 6e0u chain B Region: 35 - 193 Aligned: 151 Modelled: 157 Confidence: 99.1% Identity: 12% PDB header:hydrolase, toxin Chain: B: PDB Molecule:serine protease; PDBTitle: staphylococcus pseudintermedius exfoliative toxin exi Phyre2 PDB 5c2z chain A Region: 39 - 196 Aligned: 150 Modelled: 156 Confidence: 99.1% Identity: 17% PDB header:toxin Chain: A: PDB Molecule:exfoliative toxin d2; PDBTitle: molecular insights into the specificity of exfoliative toxins from2 staphylococcus aureus Phyre2 PDB 2w7u chain C Region: 45 - 214 Aligned: 161 Modelled: 168 Confidence: 99.0% Identity: 14% PDB header:hydrolase Chain: C: PDB Molecule:serine protease spla; PDBTitle: spla serine protease of staphylococcus aureus (2.4a) Phyre2 PDB 3cp7 chain B Region: 41 - 218 Aligned: 174 Modelled: 178 Confidence: 99.0% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:alkaline serine protease al20; PDBTitle: crystal structure of a thermostable serine protease al20 from2 extremophilic microoganism Phyre2 PDB 1zyo chain A Region: 19 - 213 Aligned: 177 Modelled: 195 Confidence: 98.9% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:serine protease; PDBTitle: crystal structure of the serine protease domain of sesbania mosaic2 virus polyprotein Phyre2 PDB 1qtf chain A Region: 35 - 205 Aligned: 165 Modelled: 171 Confidence: 98.9% Identity: 13% Fold: Trypsin-like serine proteases Superfamily: Trypsin-like serine proteases Family: Prokaryotic proteases Phyre2 PDB 2o8l chain A domain 1 Region: 36 - 214 Aligned: 173 Modelled: 179 Confidence: 98.8% Identity: 12% Fold: Trypsin-like serine proteases Superfamily: Trypsin-like serine proteases Family: Prokaryotic proteases Phyre2 PDB 2o8l chain A Region: 36 - 214 Aligned: 173 Modelled: 179 Confidence: 98.8% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:v8 protease; PDBTitle: structure of v8 protease from staphylococcus aureus Phyre2 PDB 1qy6 chain A Region: 36 - 214 Aligned: 173 Modelled: 177 Confidence: 98.8% Identity: 12% PDB header:protease Chain: A: PDB Molecule:serine protease; PDBTitle: structue of v8 protease from staphylococcus aureus Phyre2 1 c5mrtA_ 2 d2h5ca1 3 c2pfeA_ 4 d2sgaa_ 5 d2qaaa1 6 c2ouaA_ 7 d1hpga_ 8 c2ea3A_ 9 d2sfaa_ 10 d1agja_ 11 c4inkA_ 12 c6e0uB_ 13 c5c2zA_ 14 c2w7uC_ 15 c3cp7B_ 16 c1zyoA_ 17 d1qtfa_ 18 d2o8la1 19 c2o8lA_ 20 c1qy6A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228