1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	H	P	P	T	D	L	P	R	W	V	Y	L	P	A	I	A	G	I	V	F	V	A	M	P	L	V	A	I	A	I	R	V	D	W	P	R	F	W	A	L	I	T	T	P	S	S	Q	T	A	L	L	L	S	V	K	T	A	A	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	T	V	L	C	V	L	L	G	V	P	M	A	L	V	L	A	R	S	R	G	R	L	V	R	S	L	R	P	L	I	L	L	P	L	V	L	P	P	V	V	G	G	I	A	L	L	Y	A	F	G	R	L	G	L	I	G	R	Y	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	A	A	G	I	S	I	A	F	S	T	A	A	V	V	L	A	Q	T	F	V	S	L	P	Y	L	V	I	S	L	E	G	A	A	R	T	A	G	A	D	Y	E	V	V	A	A	T	L	G	A	R	P	G	T	V	W	W	R	V	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	P	L	L	L	P	G	V	V	S	G	S	V	L	A	F	A	R	S	L	G	E	F	G	A	T	L	T	F	A	G	S	R	Q	G	V	T	R	T	L	P	L	E	I	Y	L	Q	R	V	T	D	P	D	A	A	V	A	L	S	L
Secondary structure
SS confidence
Disorder																																?	?	?	?	?													?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.
Sequence		L	L	V	V	V	A	A	L	V	V	L	G	V	G	A	R	T	P	I	G	T	D	T	R
Secondary structure
SS confidence
Disorder																	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 10%) Alpha helix ( 80%) Beta strand ( 0%) TM helix ( 49%) (View membrane topology prediction)

Rank Aligned region

PDB 4tqv chain I Region: 1 - 264 Aligned: 264 Modelled: 264 Confidence: 100.0% Identity: 13% PDB header:transport protein Chain: I: PDB Molecule:algm1; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 3d31 chain C domain 1 Region: 3 - 251 Aligned: 247 Modelled: 249 Confidence: 100.0% Identity: 30% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain D Region: 3 - 251 Aligned: 247 Modelled: 249 Confidence: 100.0% Identity: 30% PDB header:transport protein Chain: D: PDB Molecule:sulfate/molybdate abc transporter, permease protein; PDBTitle: modbc from methanosarcina acetivorans Phyre2 PDB 2r6g chain F Region: 33 - 253 Aligned: 221 Modelled: 221 Confidence: 100.0% Identity: 20% PDB header:hydrolase/transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: the crystal structure of the e. coli maltose transporter Phyre2 PDB 3fh6 chain F Region: 3 - 262 Aligned: 260 Modelled: 260 Confidence: 100.0% Identity: 21% PDB header:transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: crystal structure of the resting state maltose transporter from e.2 coli Phyre2 PDB 2onk chain C Region: 8 - 251 Aligned: 240 Modelled: 244 Confidence: 100.0% Identity: 30% PDB header:membrane protein Chain: C: PDB Molecule:molybdate/tungstate abc transporter, permease PDBTitle: abc transporter modbc in complex with its binding protein2 moda Phyre2 PDB 2onk chain C domain 1 Region: 8 - 251 Aligned: 240 Modelled: 244 Confidence: 100.0% Identity: 30% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain F domain 2 Region: 35 - 253 Aligned: 219 Modelled: 218 Confidence: 100.0% Identity: 18% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain G domain 1 Region: 2 - 264 Aligned: 256 Modelled: 263 Confidence: 100.0% Identity: 22% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 4tqv chain J Region: 2 - 257 Aligned: 240 Modelled: 240 Confidence: 100.0% Identity: 14% PDB header:transport protein Chain: J: PDB Molecule:algm2; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 4ymu chain C Region: 34 - 259 Aligned: 212 Modelled: 226 Confidence: 100.0% Identity: 14% PDB header:protein binding/transport protein Chain: C: PDB Molecule:abc-type amino acid transport system, permease component; PDBTitle: crystal structure of an amino acid abc transporter complex with2 arginines and atps Phyre2 PDB 3dhw chain A domain 1 Region: 47 - 252 Aligned: 198 Modelled: 206 Confidence: 99.9% Identity: 15% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2m8g chain X Region: 149 - 179 Aligned: 31 Modelled: 31 Confidence: 57.9% Identity: 19% PDB header:transcription Chain: X: PDB Molecule:transcriptional regulator; PDBTitle: structure, function, and tethering of dna-binding domains in 542 transcriptional activators Phyre2 PDB 5kbu chain A Region: 53 - 184 Aligned: 85 Modelled: 88 Confidence: 57.9% Identity: 27% PDB header:transport protein Chain: A: PDB Molecule:glutamate receptor 2,voltage-dependent calcium channel PDBTitle: cryo-em structure of glua2-2xstz complex at 7.8 angstrom resolution Phyre2 PDB 4l5e chain A Region: 149 - 179 Aligned: 31 Modelled: 31 Confidence: 57.7% Identity: 13% PDB header:protein binding Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of a. aeolicus ntrc1 dna binding domain Phyre2 PDB 1umq chain A Region: 149 - 179 Aligned: 31 Modelled: 31 Confidence: 54.1% Identity: 10% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1umq chain A Region: 149 - 179 Aligned: 31 Modelled: 31 Confidence: 54.1% Identity: 10% PDB header:dna-binding protein Chain: A: PDB Molecule:photosynthetic apparatus regulatory protein; PDBTitle: solution structure and dna binding of the effector domain2 from the global regulator prra(rega) from r. sphaeroides:3 insights into dna binding specificity Phyre2 PDB 1fip chain A Region: 149 - 179 Aligned: 31 Modelled: 31 Confidence: 52.8% Identity: 16% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1ntc chain A Region: 148 - 179 Aligned: 32 Modelled: 32 Confidence: 51.7% Identity: 22% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1eto chain B Region: 149 - 179 Aligned: 31 Modelled: 31 Confidence: 48.8% Identity: 16% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 1 c4tqvI_ 2 d3d31c1 3 c3d31D_ 4 c2r6gF_ 5 c3fh6F_ 6 c2onkC_ 7 d2onkc1 8 d2r6gf2 9 d2r6gg1 10 c4tqvJ_ 11 c4ymuC_ 12 d3dhwa1 13 c2m8gX_ 14 c5kbuA_ 15 c4l5eA_ 16 d1umqa_ 17 c1umqA_ 18 d1fipa_ 19 d1ntca_ 20 d1etob_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34