1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	I	T	A	T	T	E	F	S	A	M	N	L	D	G	K	T	G	I	G	W	L	G	Y	I	V	I	G	G	I	A	G	W	L	A	S	K	I	V	K	G	G	G	S	G	I	L	M	N	V	V	I	G	V	V	G	A	F	G
Secondary structure
SS confidence
Disorder		?	?	?	?										?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.
Sequence		A	G	L	V	L	N	A	L	G	V	D	V	N	H	G	G	Y	W	F	T	F	F	V	A	L	G	G	A	V	V	L	L	W	I	V	G	M	V	R	K	T
Secondary structure
SS confidence
Disorder																																								?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 12%) Alpha helix ( 80%) Beta strand ( 0%) TM helix ( 59%) (View membrane topology prediction)

Rank Aligned region

PDB 5wuf chain A Region: 27 - 100 Aligned: 74 Modelled: 74 Confidence: 88.0% Identity: 19% PDB header:membrane protein Chain: A: PDB Molecule:putative membrane protein; PDBTitle: structural basis for conductance through tric cation channels Phyre2 PDB 1l7v chain A Region: 28 - 97 Aligned: 67 Modelled: 70 Confidence: 80.8% Identity: 15% Fold: ABC transporter involved in vitamin B12 uptake, BtuC Superfamily: ABC transporter involved in vitamin B12 uptake, BtuC Family: ABC transporter involved in vitamin B12 uptake, BtuC Phyre2 PDB 5h36 chain E Region: 27 - 100 Aligned: 74 Modelled: 74 Confidence: 78.5% Identity: 20% PDB header:membrane protein Chain: E: PDB Molecule:uncharacterized protein tric; PDBTitle: crystal structures of the tric trimeric intracellular cation channel2 orthologue from rhodobacter sphaeroides Phyre2 PDB 5b57 chain B Region: 28 - 99 Aligned: 69 Modelled: 72 Confidence: 78.4% Identity: 17% PDB header:metal transport Chain: B: PDB Molecule:putative hemin abc transport system, membrane protein; PDBTitle: inward-facing conformation of abc heme importer bhuuv from2 burkholderia cenocepacia Phyre2 PDB 4dbl chain B Region: 28 - 97 Aligned: 67 Modelled: 70 Confidence: 75.7% Identity: 15% PDB header:transport protein Chain: B: PDB Molecule:vitamin b12 import system permease protein btuc; PDBTitle: crystal structure of e159q mutant of btucdf Phyre2 PDB 2nq2 chain A Region: 28 - 98 Aligned: 67 Modelled: 71 Confidence: 69.6% Identity: 21% PDB header:metal transport Chain: A: PDB Molecule:hypothetical abc transporter permease protein PDBTitle: an inward-facing conformation of a putative metal-chelate2 type abc transporter. Phyre2 PDB 5h35 chain C Region: 27 - 100 Aligned: 74 Modelled: 74 Confidence: 65.3% Identity: 18% PDB header:immune system/membrane protein Chain: C: PDB Molecule:membrane protein tric; PDBTitle: crystal structures of the tric trimeric intracellular cation channel2 orthologue from sulfolobus solfataricus Phyre2 PDB 5wud chain A Region: 19 - 100 Aligned: 82 Modelled: 82 Confidence: 63.1% Identity: 21% PDB header:membrane protein Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: structural basis for conductance through tric cation channels Phyre2 PDB 4hzu chain S Region: 22 - 100 Aligned: 78 Modelled: 79 Confidence: 51.0% Identity: 21% PDB header:hydrolase, transport protein Chain: S: PDB Molecule:predicted membrane protein; PDBTitle: structure of a bacterial energy-coupling factor transporter Phyre2 PDB 4iky chain A Region: 35 - 100 Aligned: 66 Modelled: 66 Confidence: 50.4% Identity: 9% PDB header:transport protein Chain: A: PDB Molecule:di-tripeptide abc transporter (permease); PDBTitle: crystal structure of peptide transporter pot (e310q mutant) in complex2 with sulfate Phyre2 PDB 4rfs chain S Region: 3 - 100 Aligned: 98 Modelled: 98 Confidence: 46.6% Identity: 19% PDB header:hydrolase, transport protein Chain: S: PDB Molecule:substrate binding pritein s; PDBTitle: structure of a pantothenate energy coupling factor transporter Phyre2 PDB 6e9o chain A Region: 48 - 100 Aligned: 50 Modelled: 53 Confidence: 45.6% Identity: 22% PDB header:membrane protein Chain: A: PDB Molecule:d-galactonate transport; PDBTitle: e. coli d-galactonate:proton symporter mutant e133q in the outward2 substrate-bound form Phyre2 PDB 4g1u chain B Region: 28 - 95 Aligned: 65 Modelled: 68 Confidence: 44.3% Identity: 15% PDB header:transport protein/hydrolase Chain: B: PDB Molecule:hemin transport system permease protein hmuu; PDBTitle: x-ray structure of the bacterial heme transporter hmuuv from yersinia2 pestis Phyre2 PDB 6exs chain A Region: 23 - 100 Aligned: 78 Modelled: 78 Confidence: 38.6% Identity: 12% PDB header:membrane protein Chain: A: PDB Molecule:peptide abc transporter permease; PDBTitle: crystal structure of a pot family transporter in complex with2 thioalcohol conjugated peptide. Phyre2 PDB 1xoo chain A Region: 27 - 37 Aligned: 11 Modelled: 11 Confidence: 19.8% Identity: 36% PDB header:viral protein Chain: A: PDB Molecule:hemagglutinin; PDBTitle: nmr structure of g1s mutant of influenza hemagglutinin2 fusion peptide in dpc micelles at ph 5 Phyre2 PDB 1ibo chain A Region: 27 - 37 Aligned: 11 Modelled: 11 Confidence: 18.7% Identity: 36% PDB header:viral protein Chain: A: PDB Molecule:hemagglutinin ha2 chain peptide; PDBTitle: nmr structure of hemagglutinin fusion peptide in dpc2 micelles at ph 7.4 Phyre2 PDB 1ibn chain A Region: 27 - 37 Aligned: 11 Modelled: 11 Confidence: 18.7% Identity: 36% PDB header:viral protein Chain: A: PDB Molecule:hemagglutinin ha2 chain peptide; PDBTitle: nmr structure of hemagglutinin fusion peptide in dpc2 micelles at ph 5 Phyre2 PDB 1xop chain A Region: 27 - 37 Aligned: 11 Modelled: 11 Confidence: 18.3% Identity: 36% PDB header:viral protein Chain: A: PDB Molecule:hemagglutinin; PDBTitle: nmr structure of g1v mutant of influenza hemagglutinin2 fusion peptide in dpc micelles at ph 5 Phyre2 PDB 2kxa chain A Region: 27 - 37 Aligned: 11 Modelled: 11 Confidence: 17.9% Identity: 36% PDB header:viral protein, immune system Chain: A: PDB Molecule:haemagglutinin ha2 chain peptide; PDBTitle: the hemagglutinin fusion peptide (h1 subtype) at ph 7.4 Phyre2 PDB 2l4g chain A Region: 27 - 38 Aligned: 12 Modelled: 12 Confidence: 17.6% Identity: 33% PDB header:viral protein Chain: A: PDB Molecule:haemagglutinin; PDBTitle: influenza haemagglutinin fusion peptide mutant g13a Phyre2 1 c5wufA_ 2 d1l7va_ 3 c5h36E_ 4 c5b57B_ 5 c4dblB_ 6 c2nq2A_ 7 c5h35C_ 8 c5wudA_ 9 c4hzuS_ 10 c4ikyA_ 11 c4rfsS_ 12 c6e9oA_ 13 c4g1uB_ 14 c6exsA_ 15 c1xooA_ 16 c1iboA_ 17 c1ibnA_ 18 c1xopA_ 19 c2kxaA_ 20 c2l4gA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70