1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	T	V	A	P	R	R	L	A	W	T	N	A	R	Q	S	Y	P	V	R	V	A	H	V	L	S	V	N	L	A	R	V	R	A	N	P	D	P	R	A	Q	S	K	L	T	G	I	D	K	V	A	A	S	E	A	V	M	V	R	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?										?	?	?	?	?	?	?	?	?																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	G	S	M	H	A	G	V	G	S	G	L	V	G	D	T	V	G	N	P	K	L	H	G	G	D	D	Q	A	V	Y	A	Y	A	R	E	D	L	D	A	W	E	T	Q	L	H	R	T	L	H	N	G	M	F	G	E	N	L	T	T
Secondary structure
SS confidence
Disorder			?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	G	V	D	V	T	Y	A	R	I	G	E	R	W	R	I	G	S	D	G	L	V	L	E	V	S	A	P	R	I	P	C	R	T	F	A	A	F	L	D	L	R	Y	W	I	K	T	F	T	R	A	A	K	P	G	A	Y	L	R	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	A	P	G	T	V	R	A	G	D	T	I	T	V	D	Y	R	P	E	H	N	V	T	V	G	L	V	F	R	A	R	T	S	E	S	E	L	L	P	Q	L	L	A	A	D	A	L	A	A	E	L	K	A	Y	A	R	E	R	T	P
Secondary structure
SS confidence
Disorder																																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.
Sequence		S	P	P	P	V	D	S	A	D	D	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 19%) Alpha helix ( 28%) Beta strand ( 25%)

Rank Aligned region

PDB 1o65 chain A Region: 41 - 241 Aligned: 186 Modelled: 201 Confidence: 100.0% Identity: 28% Fold: PK beta-barrel domain-like Superfamily: PK beta-barrel domain-like Family: MOSC (MOCO sulphurase C-terminal) domain Phyre2 PDB 5yhh chain A Region: 18 - 240 Aligned: 191 Modelled: 198 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: A: PDB Molecule:uncharacterized conserved protein yiim; PDBTitle: crystal structure of yiim from geobacillus stearothermophilus Phyre2 PDB 1oru chain A Region: 20 - 196 Aligned: 154 Modelled: 164 Confidence: 100.0% Identity: 21% Fold: PK beta-barrel domain-like Superfamily: PK beta-barrel domain-like Family: MOSC (MOCO sulphurase C-terminal) domain Phyre2 PDB 6fw2 chain A Region: 90 - 196 Aligned: 102 Modelled: 107 Confidence: 98.4% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:mitochondrial amidoxime-reducing component 1,endolysin, PDBTitle: crystal structure of human marc1 Phyre2 PDB 2qam chain N domain 1 Region: 163 - 199 Aligned: 34 Modelled: 37 Confidence: 51.7% Identity: 38% Fold: Prokaryotic ribosomal protein L17 Superfamily: Prokaryotic ribosomal protein L17 Family: Prokaryotic ribosomal protein L17 Phyre2 PDB 2q8i chain B Region: 108 - 203 Aligned: 79 Modelled: 81 Confidence: 46.5% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase component of PDBTitle: pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug2 radicicol Phyre2 PDB 3rj1 chain P Region: 227 - 247 Aligned: 21 Modelled: 21 Confidence: 37.6% Identity: 33% PDB header:transcription Chain: P: PDB Molecule:mediator of rna polymerase ii transcription subunit 17; PDBTitle: architecture of the mediator head module Phyre2 PDB 1jvw chain A Region: 174 - 194 Aligned: 21 Modelled: 21 Confidence: 37.1% Identity: 33% Fold: FKBP-like Superfamily: FKBP-like Family: FKBP immunophilin/proline isomerase Phyre2 PDB 1gd8 chain A Region: 163 - 190 Aligned: 26 Modelled: 28 Confidence: 32.6% Identity: 31% Fold: Prokaryotic ribosomal protein L17 Superfamily: Prokaryotic ribosomal protein L17 Family: Prokaryotic ribosomal protein L17 Phyre2 PDB 1vw4 chain L Region: 171 - 198 Aligned: 27 Modelled: 28 Confidence: 32.3% Identity: 33% PDB header:ribosome Chain: L: PDB Molecule:54s ribosomal protein l8, mitochondrial; PDBTitle: structure of the yeast mitochondrial large ribosomal subunit Phyre2 PDB 2dnc chain A Region: 108 - 203 Aligned: 79 Modelled: 81 Confidence: 31.0% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase protein x component; PDBTitle: solution structure of rsgi ruh-054, a lipoyl domain from2 human 2-oxoacid dehydrogenase Phyre2 PDB 1q6h chain A Region: 174 - 194 Aligned: 21 Modelled: 21 Confidence: 30.1% Identity: 29% Fold: FKBP-like Superfamily: FKBP-like Family: FKBP immunophilin/proline isomerase Phyre2 PDB 1y8o chain B domain 1 Region: 113 - 203 Aligned: 74 Modelled: 76 Confidence: 28.8% Identity: 18% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 2vcd chain A Region: 174 - 194 Aligned: 21 Modelled: 21 Confidence: 28.3% Identity: 43% PDB header:isomerase Chain: A: PDB Molecule:outer membrane protein mip; PDBTitle: solution structure of the fkbp-domain of legionella pneumophila mip in2 complex with rapamycin Phyre2 PDB 1fd9 chain A Region: 174 - 194 Aligned: 21 Modelled: 21 Confidence: 26.6% Identity: 43% Fold: FKBP-like Superfamily: FKBP-like Family: FKBP immunophilin/proline isomerase Phyre2 PDB 1vje chain A Region: 143 - 181 Aligned: 39 Modelled: 39 Confidence: 26.3% Identity: 26% Fold: LuxS/MPP-like metallohydrolase Superfamily: LuxS/MPP-like metallohydrolase Family: Autoinducer-2 production protein LuxS Phyre2 PDB 2gez chain E Region: 108 - 152 Aligned: 42 Modelled: 45 Confidence: 25.3% Identity: 33% PDB header:hydrolase Chain: E: PDB Molecule:l-asparaginase alpha subunit; PDBTitle: crystal structure of potassium-independent plant asparaginase Phyre2 PDB 1q6u chain A Region: 174 - 194 Aligned: 21 Modelled: 21 Confidence: 23.8% Identity: 29% PDB header:isomerase Chain: A: PDB Molecule:fkbp-type peptidyl-prolyl cis-trans isomerase fkpa; PDBTitle: crystal structure of fkpa from escherichia coli Phyre2 PDB 1j98 chain A Region: 143 - 181 Aligned: 39 Modelled: 39 Confidence: 23.0% Identity: 21% Fold: LuxS/MPP-like metallohydrolase Superfamily: LuxS/MPP-like metallohydrolase Family: Autoinducer-2 production protein LuxS Phyre2 PDB 3gwq chain B Region: 115 - 186 Aligned: 52 Modelled: 56 Confidence: 21.9% Identity: 29% PDB header:lyase Chain: B: PDB Molecule:d-serine deaminase; PDBTitle: crystal structure of a putative d-serine deaminase (bxe_a4060) from2 burkholderia xenovorans lb400 at 2.00 a resolution Phyre2 1 d1o65a_ 2 c5yhhA_ 3 d1orua_ 4 c6fw2A_ 5 d2qamn1 6 c2q8iB_ 7 c3rj1P_ 8 d1jvwa_ 9 d1gd8a_ 10 c1vw4L_ 11 c2dncA_ 12 d1q6ha_ 13 d1y8ob1 14 c2vcdA_ 15 d1fd9a_ 16 d1vjea_ 17 c2gezE_ 18 c1q6uA_ 19 d1j98a_ 20 c3gwqB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99