1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.
Sequence		V	V	P	V	D	L	R	R	D	W	P	T	P	L	R	Q	A	G	F	D	P	N	Q	P	S	A	W	L	A	E	G	L	L	A	F	L	P	P	D	A	Q	D	R	L	L	D	N	I	T	A	L	S	A	P	G	S	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																												?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 25%) Alpha helix ( 44%) Beta strand ( 14%)

Rank Aligned region

PDB 2uyo chain A domain 1 Region: 1 - 57 Aligned: 57 Modelled: 57 Confidence: 99.7% Identity: 63% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: ML2640-like Phyre2 PDB 1rjd chain A Region: 1 - 56 Aligned: 56 Modelled: 56 Confidence: 99.4% Identity: 20% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Leucine carboxy methyltransferase Ppm1 Phyre2 PDB 3iei chain D Region: 1 - 50 Aligned: 50 Modelled: 50 Confidence: 99.2% Identity: 24% PDB header:transferase Chain: D: PDB Molecule:leucine carboxyl methyltransferase 1; PDBTitle: crystal structure of human leucine carboxylmethyltransferase-1 in2 complex with s-adenosyl homocysteine Phyre2 PDB 3mnt chain A Region: 1 - 56 Aligned: 56 Modelled: 56 Confidence: 99.2% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:leucine carboxyl methyltransferase 1; PDBTitle: crystal structure of human leucine carboxyl methyltransferase 1 Phyre2 PDB 2zwa chain A Region: 1 - 52 Aligned: 52 Modelled: 52 Confidence: 97.9% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:leucine carboxyl methyltransferase 2; PDBTitle: crystal structure of trna wybutosine synthesizing enzyme2 tyw4 Phyre2 PDB 2qe6 chain B Region: 1 - 57 Aligned: 57 Modelled: 57 Confidence: 97.8% Identity: 32% PDB header:transferase Chain: B: PDB Molecule:uncharacterized protein tfu_2867; PDBTitle: crystal structure of a putative methyltransferase (tfu_2867) from2 thermobifida fusca yx at 1.95 a resolution Phyre2 PDB 3giw chain A Region: 1 - 57 Aligned: 57 Modelled: 57 Confidence: 92.9% Identity: 16% PDB header:unknown function Chain: A: PDB Molecule:protein of unknown function duf574; PDBTitle: crystal structure of a duf574 family protein (sav_2177) from2 streptomyces avermitilis ma-4680 at 1.45 a resolution Phyre2 PDB 6e7k chain B Region: 11 - 31 Aligned: 21 Modelled: 21 Confidence: 37.3% Identity: 10% PDB header:hydrolase Chain: B: PDB Molecule:lipoprotein lipase; PDBTitle: structure of the lipoprotein lipase gpihbp1 complex that mediates2 plasma triglyceride hydrolysis Phyre2 PDB 1hpl chain B Region: 11 - 31 Aligned: 21 Modelled: 21 Confidence: 33.6% Identity: 14% PDB header:hydrolase(carboxylic esterase) Chain: B: PDB Molecule:lipase; PDBTitle: horse pancreatic lipase. the crystal structure at 2.3 angstroms2 resolution Phyre2 PDB 1rp1 chain A domain 2 Region: 11 - 31 Aligned: 21 Modelled: 21 Confidence: 33.3% Identity: 14% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Pancreatic lipase, N-terminal domain Phyre2 PDB 2pvs chain B Region: 11 - 31 Aligned: 21 Modelled: 21 Confidence: 31.4% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:pancreatic lipase-related protein 2; PDBTitle: structure of human pancreatic lipase related protein 22 mutant n336q Phyre2 PDB 1hpl chain A domain 2 Region: 11 - 31 Aligned: 21 Modelled: 21 Confidence: 31.3% Identity: 14% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Pancreatic lipase, N-terminal domain Phyre2 PDB 1eth chain A domain 2 Region: 11 - 31 Aligned: 21 Modelled: 21 Confidence: 30.2% Identity: 14% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Pancreatic lipase, N-terminal domain Phyre2 PDB 1af7 chain A domain 2 Region: 26 - 55 Aligned: 30 Modelled: 30 Confidence: 29.5% Identity: 17% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Chemotaxis receptor methyltransferase CheR, C-terminal domain Phyre2 PDB 2ppl chain A Region: 11 - 31 Aligned: 21 Modelled: 21 Confidence: 28.9% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:pancreatic lipase-related protein 1; PDBTitle: human pancreatic lipase-related protein 1 Phyre2 PDB 1gpl chain A Region: 11 - 31 Aligned: 21 Modelled: 21 Confidence: 28.3% Identity: 14% PDB header:serine esterase Chain: A: PDB Molecule:rp2 lipase; PDBTitle: rp2 lipase Phyre2 PDB 1gpl chain A domain 2 Region: 11 - 31 Aligned: 21 Modelled: 21 Confidence: 27.9% Identity: 14% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Pancreatic lipase, N-terminal domain Phyre2 PDB 1bu8 chain A domain 2 Region: 12 - 31 Aligned: 20 Modelled: 20 Confidence: 27.5% Identity: 10% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Pancreatic lipase, N-terminal domain Phyre2 PDB 1co6 chain A Region: 35 - 57 Aligned: 23 Modelled: 23 Confidence: 27.4% Identity: 22% Fold: Cytochrome c Superfamily: Cytochrome c Family: monodomain cytochrome c Phyre2 PDB 1lpb chain B domain 2 Region: 11 - 31 Aligned: 21 Modelled: 21 Confidence: 26.1% Identity: 14% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Pancreatic lipase, N-terminal domain Phyre2 1 d2uyoa1 2 d1rjda_ 3 c3ieiD_ 4 c3mntA_ 5 c2zwaA_ 6 c2qe6B_ 7 c3giwA_ 8 c6e7kB_ 9 c1hplB_ 10 d1rp1a2 11 c2pvsB_ 12 d1hpla2 13 d1etha2 14 d1af7a2 15 c2pplA_ 16 c1gplA_ 17 d1gpla2 18 d1bu8a2 19 d1co6a_ 20 d1lpbb2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71