Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD1899c_(lppD)_2145221_2146252
DateFri Aug 2 13:30:51 BST 2019
Unique Job ID1097483daef1183e
SequenceMSRAAGLPRL ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:50.698 Y:43.235 Z:47.998
Model (left) based on template c5fszA_
Top template information
PDB header:hydrolase
Chain: A: PDB Molecule:macrodomain;
PDBTitle: crystal structure of trypanosoma cruzi macrodomain
Confidence and coverage
Confidence:100.0% Coverage: 57%
196 residues ( 57% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

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Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c5fszA_



100.0 28
PDB header:hydrolase
Chain: A: PDB Molecule:macrodomain;
PDBTitle: crystal structure of trypanosoma cruzi macrodomain
2c5iitC_



100.0 26
PDB header:inositol phosphate binding protein
Chain: C: PDB Molecule:vacuolar transporter chaperone 4,core histone macro-h2a.1;
PDBTitle: structure of spx domain of the yeast inorganic polyphophate polymerase2 vtc4 crystallized by carrier-driven crystallization in fusion with3 the macro domain of human histone macroh2a1.1
3c5fsuA_



100.0 33
PDB header:hydrolase
Chain: A: PDB Molecule:macrodomain;
PDBTitle: crystal structure of trypanosoma brucei macrodomain2 (crystal form 1)
4c4iqyB_



100.0 28
PDB header:hydrolase
Chain: B: PDB Molecule:o-acetyl-adp-ribose deacetylase macrod2;
PDBTitle: crystal structure of the human protein-proximal adp-ribosyl-hydrolase2 macrod2
5c5kivA_



100.0 28
PDB header:hydrolase
Chain: A: PDB Molecule:protein-adp-ribose hydrolase;
PDBTitle: crystal structure of saumacro (sav0325)
6c2x47A_



100.0 32
PDB header:signaling protein
Chain: A: PDB Molecule:macro domain-containing protein 1;
PDBTitle: crystal structure of human macrod1
7d1zr5a1



100.0 22
Fold:Macro domain-like
Superfamily:Macro domain-like
Family:Macro domain
8c3vfqA_



100.0 31
PDB header:transferase
Chain: A: PDB Molecule:poly [adp-ribose] polymerase 14;
PDBTitle: human parp14 (artd8, bal2) - macro domains 1 and 2 in complex with2 adenosine-5-diphosphoribose
9c4umlA_



100.0 24
PDB header:signaling protein
Chain: A: PDB Molecule:ganglioside-induced differentiation-associated protein 2;
PDBTitle: crystal structure of ganglioside induced differentiation2 associated protein 2 (gdap2) macro domain
10c1zr5B_



100.0 22
PDB header:gene regulation
Chain: B: PDB Molecule:h2afy protein;
PDBTitle: crystal structure of the macro-domain of human core histone variant2 macroh2a1.2
11c2xd7B_



100.0 21
PDB header:dna binding protein
Chain: B: PDB Molecule:core histone macro-h2a.2;
PDBTitle: crystal structure of the macro domain of human core histone h2a
12d1yd9a1



100.0 24
Fold:Macro domain-like
Superfamily:Macro domain-like
Family:Macro domain
13c4ablA_



100.0 22
PDB header:transferase
Chain: A: PDB Molecule:poly [adp-ribose] polymerase 14;
PDBTitle: human parp14 (artd8, bal2) - macro domain 3
14c3q71A_



100.0 26
PDB header:transferase
Chain: A: PDB Molecule:poly [adp-ribose] polymerase 14;
PDBTitle: human parp14 (artd8) - macro domain 2 in complex with adenosine-5-2 diphosphoribose
15c3kh6A_



100.0 20
PDB header:transferase
Chain: A: PDB Molecule:poly [adp-ribose] polymerase 15;
PDBTitle: human poly(adp-ribose) polymerase 15, macro domain 2 in complex with2 adenosine-5-diphosphoribose
16c3q6zA_



100.0 31
PDB header:transferase
Chain: A: PDB Molecule:poly [adp-ribose] polymerase 14;
PDBTitle: human parp14 (artd8)-macro domain 1 in complex with adenosine-5-2 diphosphoribose
17d1vhua_



100.0 32
Fold:Macro domain-like
Superfamily:Macro domain-like
Family:Macro domain
18c5ailA_



100.0 22
PDB header:transcription
Chain: A: PDB Molecule:poly [adp-ribose] polymerase 9;
PDBTitle: human parp9 2nd macrodomain
19c5l9kB_



100.0 24
PDB header:hydrolase
Chain: B: PDB Molecule:macrod-type macrodomain;
PDBTitle: oceanobacillus iheyensis macrodomain with adpr
20d1spva_



100.0 33
Fold:Macro domain-like
Superfamily:Macro domain-like
Family:Macro domain
21d2acfa1



not modelled 100.0 26
Fold:Macro domain-like
Superfamily:Macro domain-like
Family:Macro domain
22c5dusA_



not modelled 100.0 20
PDB header:viral protein
Chain: A: PDB Molecule:orf1a;
PDBTitle: crystal structure of mers-cov macro domain in complex with adp-ribose
23c2vriA_



not modelled 100.0 22
PDB header:viral protein
Chain: A: PDB Molecule:non-structural protein 3;
PDBTitle: structure of the nsp3 x-domain of human coronavirus nl63
24c3ejfA_



not modelled 100.0 21
PDB header:hydrolase
Chain: A: PDB Molecule:non-structural protein 3;
PDBTitle: crystal structure of ibv x-domain at ph 8.5
25c2dx6B_



not modelled 100.0 39
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hypothetical protein ttha0132;
PDBTitle: crystal structure of conserved hypothetical protein, ttha0132 from2 thermus thermophilus hb8
26c3ew5B_



not modelled 100.0 25
PDB header:rna binding protein
Chain: B: PDB Molecule:macro domain of non-structural protein 3;
PDBTitle: structure of the tetragonal crystal form of x (adrp) domain2 from fcov
27c3ejgA_



not modelled 100.0 20
PDB header:hydrolase
Chain: A: PDB Molecule:non-structural protein 3;
PDBTitle: crystal structure of hcov-229e x-domain
28c3gqeA_



not modelled 100.0 18
PDB header:viral protein
Chain: A: PDB Molecule:non-structural protein 3;
PDBTitle: crystal structure of macro domain of venezuelan equine encephalitis2 virus
29c5iq5A_



not modelled 100.0 22
PDB header:viral protein
Chain: A: PDB Molecule:macro domain;
PDBTitle: nmr solution structure of mayaro virus macro domain
30c3ewqA_



not modelled 100.0 20
PDB header:hydrolase
Chain: A: PDB Molecule:non-structural protein 3;
PDBTitle: hcov-229e nsp3 adrp domain
31c3gpqA_



not modelled 100.0 19
PDB header:viral protein/rna
Chain: A: PDB Molecule:non-structural protein 3;
PDBTitle: crystal structure of macro domain of chikungunya virus in complex with2 rna
32c5m3iB_



not modelled 100.0 19
PDB header:antitoxin
Chain: B: PDB Molecule:rnase iii inhibitor;
PDBTitle: macrodomain of mycobacterium tuberculosis darg
33c5m31A_



not modelled 100.0 22
PDB header:antitoxin
Chain: A: PDB Molecule:appr-1-p processing domain protein;
PDBTitle: macrodomain of thermus aquaticus darg
34c4guaB_



not modelled 100.0 20
PDB header:hydrolase
Chain: B: PDB Molecule:non-structural polyprotein;
PDBTitle: alphavirus p23pro-zbd
35c2eeeA_



not modelled 99.9 13
PDB header:gene regulation
Chain: A: PDB Molecule:uncharacterized protein c6orf130;
PDBTitle: solution structure of the a1pp domain from human protein2 c6orf130
36c5lw0A_



not modelled 99.9 29
PDB header:adp-ribose-binding protein
Chain: A: PDB Molecule:basic helix-loop-helix, putative, expressed;
PDBTitle: oryza sativa apl macrodomain in complex with adp-ribose
37d1njra_



not modelled 99.9 19
Fold:Macro domain-like
Superfamily:Macro domain-like
Family:Macro domain
38c5e3bA_



not modelled 99.9 20
PDB header:hydrolase
Chain: A: PDB Molecule:macrodomain protein;
PDBTitle: structure of macrodomain protein from streptomyces coelicolor
39d2fg1a1



not modelled 99.9 13
Fold:Macro domain-like
Superfamily:Macro domain-like
Family:Macro domain
40c5zdcL_



not modelled 98.7 23
PDB header:hydrolase
Chain: L: PDB Molecule:poly adp-ribose glycohydrolase;
PDBTitle: crystal structure of poly(adp-ribose) glycohydrolase (parg) from2 deinococcus radiodurans in complex with adp-ribose (p32)
41c3siiA_



not modelled 98.5 32
PDB header:hydrolase/hydrolase inhibitor
Chain: A: PDB Molecule:poly(adp-ribose) glycohydrolase;
PDBTitle: the x-ray crystal structure of poly(adp-ribose) glycohydrolase bound2 to the inhibitor adp-hpd from thermomonospora curvata
42c5lw6A_



not modelled 98.4 8
PDB header:adp-ribose binding protein
Chain: A: PDB Molecule:ddb_g0293866;
PDBTitle: crystal structure of a se-met substituted dictyostelium discoideum2 adp-ribose binding macrodomain (residues 342-563) of ddb_g0293866
43d1gyta1



not modelled 97.6 13
Fold:Macro domain-like
Superfamily:Macro domain-like
Family:Leucine aminopeptidase (Aminopeptidase A), N-terminal domain
44c6omeA_



not modelled 92.5 10
PDB header:hydrolase
Chain: A: PDB Molecule:probable cytosol aminopeptidase;
PDBTitle: crystal structure of a probable cytosol aminopeptidase (leucine2 aminopeptidase, lap) from chlamydia trachomatis d/uw-3/cx
45c1gytG_



not modelled 91.4 13
PDB header:hydrolase
Chain: G: PDB Molecule:cytosol aminopeptidase;
PDBTitle: e. coli aminopeptidase a (pepa)
46c3jruB_



not modelled 85.0 13
PDB header:hydrolase
Chain: B: PDB Molecule:probable cytosol aminopeptidase;
PDBTitle: crystal structure of leucyl aminopeptidase (pepa) from xoo0834,2 xanthomonas oryzae pv. oryzae kacc10331
47c3kzwD_



not modelled 66.4 8
PDB header:hydrolase
Chain: D: PDB Molecule:cytosol aminopeptidase;
PDBTitle: crystal structure of cytosol aminopeptidase from staphylococcus aureus2 col
48c3h8gC_



not modelled 61.4 12
PDB header:hydrolase
Chain: C: PDB Molecule:cytosol aminopeptidase;
PDBTitle: bestatin complex structure of leucine aminopeptidase from pseudomonas2 putida
49c5gukA_



not modelled 49.1 17
PDB header:biosynthetic protein
Chain: A: PDB Molecule:cyclolavandulyl diphosphate synthase;
PDBTitle: crystal structure of apo form of cyclolavandulyl diphosphate synthase2 (clds) from streptomyces sp. cl190
50c2vg2C_



not modelled 47.9 21
PDB header:transferase
Chain: C: PDB Molecule:undecaprenyl pyrophosphate synthetase;
PDBTitle: rv2361 with ipp
51c5hc7A_



not modelled 45.8 20
PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:prenyltransference for protein;
PDBTitle: crystal structure of lavandulyl diphosphate synthase from lavandula x2 intermedia in complex with s-thiolo-isopentenyldiphosphate
52c4h8eA_



not modelled 37.7 19
PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:undecaprenyl pyrophosphate synthase;
PDBTitle: structure of s. aureus undecaprenyl diphosphate synthase in complex2 with fpp and sulfate
53c5wggA_



not modelled 30.9 11
PDB header:peptide binding protein
Chain: A: PDB Molecule:radical sam domain protein;
PDBTitle: structural insights into thioether bond formation in the biosynthesis2 of sactipeptides
54c4g56C_



not modelled 30.0 26
PDB header:transferase
Chain: C: PDB Molecule:hsl7 protein;
PDBTitle: crystal structure of full length prmt5/mep50 complexes from xenopus2 laevis
55c2k19A_



not modelled 28.9 45
PDB header:antimicrobial protein
Chain: A: PDB Molecule:putative piscicolin 126 immunity protein;
PDBTitle: nmr solution structure of pisi
56c3ua4A_



not modelled 26.6 21
PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 5;
PDBTitle: crystal structure of protein arginine methyltransferase prmt5
57c4dqvA_



not modelled 26.5 33
PDB header:ligase
Chain: A: PDB Molecule:probable peptide synthetase nrp (peptide synthase);
PDBTitle: crystal structure of reductase (r) domain of non-ribosomal peptide2 synthetase from mycobacterium tuberculosis
58c5v1tA_



not modelled 23.5 13
PDB header:metal binding protein
Chain: A: PDB Molecule:radical sam;
PDBTitle: crystal structure of streptococcus suis suib bound to precursor2 peptide suia
59c5th5C_



not modelled 21.0 14
PDB header:lyase
Chain: C: PDB Molecule:7-carboxy-7-deazaguanine synthase;
PDBTitle: crystal structure of quee from bacillus subtilis with 6-carboxypterin-2 5'-deoxyadenosyl ester bound
60c2h8bB_



not modelled 19.6 47
PDB header:hormone/growth factor
Chain: B: PDB Molecule:insulin-like 3;
PDBTitle: solution structure of insl3
61d1mlda1



not modelled 19.1 7
Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
62c4q9mA_



not modelled 18.5 14
PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:isoprenyl transferase;
PDBTitle: crystal structure of upps in complex with fpp and an allosteric2 inhibitor
63c5n4kA_



not modelled 17.8 15
PDB header:rna binding protein
Chain: A: PDB Molecule:nucleoprotein;
PDBTitle: n-terminal domain of a human coronavirus nl63 nucleocapsid protein
64d1gnfa_



not modelled 15.9 36
Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:Erythroid transcription factor GATA-1
65c3ugsB_



not modelled 15.8 16
PDB header:transferase
Chain: B: PDB Molecule:undecaprenyl pyrophosphate synthase;
PDBTitle: crystal structure of a probable undecaprenyl diphosphate synthase2 (upps) from campylobacter jejuni
66c4pg8B_



not modelled 15.1 22
PDB header:oxidoreductase
Chain: B: PDB Molecule:homoserine dehydrogenase;
PDBTitle: crystal structure of s. aureus homoserine dehydrogenase at ph8.5
67c5msuC_



not modelled 14.9 30
PDB header:oxidoreductase
Chain: C: PDB Molecule:carboxylic acid reductase;
PDBTitle: structure of the r domain of carboxylic acid reductase (car) from2 mycobacterium marinum in complex with nadp, p21 form
68d2vuti1



not modelled 14.5 31
Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:Erythroid transcription factor GATA-1
69c6bxwA_



not modelled 13.3 23
PDB header:membrane protein
Chain: A: PDB Molecule:mitochondrial association factor 1;
PDBTitle: crystal structure of toxoplasma gondii mitochondrial association2 factor 1 b (maf1b) in complex with adpribose
70c2kaeA_



not modelled 12.9 31
PDB header:transcription/dna
Chain: A: PDB Molecule:gata-type transcription factor;
PDBTitle: data-driven model of med1:dna complex
71c3a46B_



not modelled 12.9 27
PDB header:hydrolase
Chain: B: PDB Molecule:formamidopyrimidine-dna glycosylase;
PDBTitle: crystal structure of mvnei1/thf complex
72c5b37A_



not modelled 12.2 25
PDB header:oxidoreductase
Chain: A: PDB Molecule:tryptophan dehydrogenase;
PDBTitle: crystal structure of l-tryptophan dehydrogenase from nostoc2 punctiforme
73d1hyea1



not modelled 11.9 14
Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
74d1v5ma_



not modelled 11.7 25
Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Pleckstrin-homology domain (PH domain)
75d2amxa1



not modelled 11.5 8
Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Adenosine/AMP deaminase
76d1sska_



not modelled 11.4 56
Fold:Coronavirus RNA-binding domain
Superfamily:Coronavirus RNA-binding domain
Family:Coronavirus RNA-binding domain
77c3g5rA_



not modelled 11.2 22
PDB header:transferase
Chain: A: PDB Molecule:methylenetetrahydrofolate--trna-(uracil-5-)-
PDBTitle: crystal structure of thermus thermophilus trmfo in complex with2 tetrahydrofolate
78c4c4aA_



not modelled 10.5 13
PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 7;
PDBTitle: crystal structure of mouse protein arginine methyltransferase 7 in2 complex with sah
79c5xk9F_



not modelled 10.1 9
PDB header:transferase
Chain: F: PDB Molecule:undecaprenyl diphosphate synthase;
PDBTitle: crystal structure of isosesquilavandulyl diphosphate synthase from2 streptomyces sp. strain cnh-189 in complex with gspp and dmapp
80c4zr8B_



not modelled 10.1 21
PDB header:lyase
Chain: B: PDB Molecule:uroporphyrinogen decarboxylase;
PDBTitle: structure of uroporphyrinogen decarboxylase from acinetobacter2 baumannii
81d1y0ja1



not modelled 9.9 29
Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:Erythroid transcription factor GATA-1
82c2lo9A_



not modelled 9.9 75
PDB header:toxin
Chain: A: PDB Molecule:mu-conotoxin buiiib;
PDBTitle: nmr solution structure of mu-contoxin buiiib
83c2mxfA_



not modelled 9.9 45
PDB header:transcription regulator/dna
Chain: A: PDB Molecule:mvat;
PDBTitle: structure of the dna complex of the c-terminal domain of mvat
84c5cw9A_



not modelled 9.8 19
PDB header:de novo protein
Chain: A: PDB Molecule:de novo designed ferredoxin-ferredoxin domain insertion
PDBTitle: crystal structure of de novo designed ferredoxin-ferredoxin domain2 insertion protein
85c1jpkA_



not modelled 9.6 21
PDB header:lyase
Chain: A: PDB Molecule:uroporphyrinogen decarboxylase;
PDBTitle: gly156asp mutant of human urod, human uroporphyrinogen iii2 decarboxylase
86c5vslB_



not modelled 9.5 11
PDB header:antiviral protein
Chain: B: PDB Molecule:radical s-adenosyl methionine domain-containing protein 2;
PDBTitle: crystal structure of viperin with bound [4fe-4s] cluster and s-2 adenosylhomocysteine (sah)
87c2locA_



not modelled 9.4 75
PDB header:toxin
Chain: A: PDB Molecule:mu-conotoxin buiiib;
PDBTitle: conotoxin analogue [d-ala2]buiiib
88c6efnA_



not modelled 9.3 14
PDB header:oxidoreductase
Chain: A: PDB Molecule:sporulation killing factor maturation protein skfb;
PDBTitle: structure of a ripp maturase, skfb
89c5imuA_



not modelled 9.2 78
PDB header:signaling protein
Chain: A: PDB Molecule:tat (twin-arginine translocation) pathway signal sequence
PDBTitle: a fragment of conserved hypothetical protein rv3899c (residues 184-2 410) from mycobacterium tuberculosis
90d1r8ka_



not modelled 9.1 12
Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:PdxA-like
91c6nd1A_



not modelled 9.1 50
PDB header:protein transport
Chain: A: PDB Molecule:protein translocation protein sec63;
PDBTitle: cryoem structure of the sec complex from yeast
92d1c0pa1



not modelled 8.9 35
Fold:Nucleotide-binding domain
Superfamily:Nucleotide-binding domain
Family:D-aminoacid oxidase, N-terminal domain
93c4ndlC_



not modelled 8.8 53
PDB header:de novo protein
Chain: C: PDB Molecule:enh-c2b, computational designed homodimer;
PDBTitle: computational design and experimental verification of a symmetric2 homodimer
94c3hd4A_



not modelled 8.8 53
PDB header:viral protein
Chain: A: PDB Molecule:nucleoprotein;
PDBTitle: mhv nucleocapsid protein ntd
95c2vfwB_



not modelled 8.6 15
PDB header:transferase
Chain: B: PDB Molecule:short-chain z-isoprenyl diphosphate synthetase;
PDBTitle: rv1086 native
96c3ckvA_



not modelled 8.5 15
PDB header:unknown function
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of a mycobacterial protein
97d2cmda1



not modelled 8.1 8
Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
98c3ingA_



not modelled 8.0 9
PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: crystal structure of homoserine dehydrogenase (np_394635.1) from2 thermoplasma acidophilum at 1.95 a resolution
99c6pdmA_



not modelled 7.9 8
PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 9;
PDBTitle: crystal structure of human protein arginine methyltransferase 92 (prmt9)

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