1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		L	I	G	P	A	R	R	S	T	T	T	R	R	S	T	P	R	A	D	R	L	A	G	C	W	C	L	P	G	A	I	C	Q	T	P	R	A	W	W	S	Q	A	R	R	D	G	D	D	E	T	G	M	R	R	K	G	A	E	M	C
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																								?	?	?	?	?	?	?	?	?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		W	M	C	D	H	P	E	A	T	A	E	E	Y	L	D	E	V	Y	G	I	M	L	M	H	G	W	A	V	Q	H	V	E	C	E	R	R	P	F	A	Y	T	V	G	L	T	R	R	G	L	P	E	L	V	V	T	G	L	S	P	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	G	Q	R	L	L	N	I	A	A	R	R	A	L	V	G	D	L	L	T	P	G	M	Q	T	T	L	P	A	G	P	L	V	E	T	V	Q	A	T	H	P	D	A	H	L	Y	C	A	I	A	I	F	G	D	K	V	T	A	L	Q
Secondary structure
SS confidence
Disorder																?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.
Sequence		L	V	W	A	D	R	R	G	R	W	P	W	A	A	D	F	D	E	G	R	G	T	Q	P	V	L	G	M	R	A	T	R	R	S	A
Secondary structure
SS confidence
Disorder																													?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 37%) Beta strand ( 11%)

Rank Aligned region

PDB 2l6p chain A Region: 178 - 193 Aligned: 16 Modelled: 16 Confidence: 60.2% Identity: 38% PDB header:structure genomics, unknown function Chain: A: PDB Molecule:phac1, phac2 and phad genes; PDBTitle: nmr solution structure of the protein np_253742.1 Phyre2 PDB 3luu chain A Region: 178 - 193 Aligned: 16 Modelled: 16 Confidence: 60.1% Identity: 38% PDB header:biosynthetic protein Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of protein with unknown function which belongs to2 pfam duf971 family (afe_2189) from acidithiobacillus ferrooxidans3 atcc 23270 at 1.93 a resolution Phyre2 PDB 2fb1 chain A Region: 22 - 52 Aligned: 31 Modelled: 30 Confidence: 53.6% Identity: 29% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of protein bt0354 from bacteroides thetaiotaomicron Phyre2 PDB 2l6n chain A Region: 178 - 193 Aligned: 16 Modelled: 16 Confidence: 45.9% Identity: 38% PDB header:structure genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein yp_001092504.1; PDBTitle: nmr solution structure of the protein yp_001092504.1 Phyre2 PDB 4i62 chain A Region: 78 - 130 Aligned: 49 Modelled: 53 Confidence: 44.6% Identity: 16% PDB header:transport protein Chain: A: PDB Molecule:amino acid abc transporter, periplasmic amino acid-binding PDBTitle: 1.05 angstrom crystal structure of an amino acid abc transporter2 substrate-binding protein abpa from streptococcus pneumoniae canada3 mdr_19a bound to l-arginine Phyre2 PDB 2yyh chain C Region: 23 - 53 Aligned: 31 Modelled: 31 Confidence: 41.8% Identity: 26% PDB header:hydrolase Chain: C: PDB Molecule:8-oxo-dgtpase domain; PDBTitle: crystal structure of nudix family protein from aquifex aeolicus Phyre2 PDB 1h9h chain I Region: 13 - 35 Aligned: 23 Modelled: 23 Confidence: 36.2% Identity: 43% Fold: Knottins (small inhibitors, toxins, lectins) Superfamily: Plant inhibitors of proteinases and amylases Family: Plant inhibitors of proteinases and amylases Phyre2 PDB 3uv1 chain B Region: 69 - 119 Aligned: 51 Modelled: 51 Confidence: 36.1% Identity: 16% PDB header:allergen Chain: B: PDB Molecule:der f 7 allergen; PDBTitle: crystal structure a major allergen from dust mite Phyre2 PDB 3i9x chain A Region: 16 - 52 Aligned: 37 Modelled: 37 Confidence: 33.2% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:mutt/nudix family protein; PDBTitle: crystal structure of a mutt/nudix family protein from listeria innocua Phyre2 PDB 2fml chain B Region: 22 - 52 Aligned: 31 Modelled: 31 Confidence: 29.9% Identity: 26% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:mutt/nudix family protein; PDBTitle: crystal structure of mutt/nudix family protein from enterococcus2 faecalis Phyre2 PDB 2m2q chain A Region: 22 - 31 Aligned: 10 Modelled: 10 Confidence: 26.9% Identity: 70% PDB header:unknown function Chain: A: PDB Molecule:inhibitor cystine knot peptide mch-1; PDBTitle: solution structure of mch-1: a novel inhibitor cystine knot peptide2 from momordica charantia Phyre2 PDB 1hw4 chain A Region: 66 - 87 Aligned: 20 Modelled: 22 Confidence: 26.5% Identity: 30% PDB header:transferase Chain: A: PDB Molecule:thymidylate synthase; PDBTitle: structure of thymidylate synthase suggests advantages of chemotherapy2 with noncompetitive inhibitors Phyre2 PDB 3egy chain X Region: 66 - 85 Aligned: 18 Modelled: 20 Confidence: 25.1% Identity: 33% PDB header:transferase Chain: X: PDB Molecule:thymidylate synthase; PDBTitle: crystal structure of human thymidyalte synthase a191k with loop 181-2 197 stabilized in the inactive conformation Phyre2 PDB 2fml chain A domain 2 Region: 22 - 52 Aligned: 31 Modelled: 31 Confidence: 25.0% Identity: 26% Fold: Nudix Superfamily: Nudix Family: BT0354 N-terminal domain-like Phyre2 PDB 5t3p chain B Region: 15 - 55 Aligned: 41 Modelled: 41 Confidence: 24.6% Identity: 32% PDB header:hydrolase Chain: B: PDB Molecule:peroxisomal coenzyme a diphosphatase nudt7; PDBTitle: crystal structure of human peroxisomal coenzyme a diphosphatase nudt7 Phyre2 PDB 5cw9 chain A Region: 98 - 135 Aligned: 38 Modelled: 38 Confidence: 24.0% Identity: 37% PDB header:de novo protein Chain: A: PDB Molecule:de novo designed ferredoxin-ferredoxin domain insertion PDBTitle: crystal structure of de novo designed ferredoxin-ferredoxin domain2 insertion protein Phyre2 PDB 6btm chain B Region: 59 - 66 Aligned: 8 Modelled: 8 Confidence: 23.8% Identity: 50% PDB header:membrane protein Chain: B: PDB Molecule:alternative complex iii subunit b; PDBTitle: structure of alternative complex iii from flavobacterium johnsoniae2 (wild type) Phyre2 PDB 1hvy chain A Region: 66 - 87 Aligned: 20 Modelled: 22 Confidence: 23.2% Identity: 30% Fold: Thymidylate synthase/dCMP hydroxymethylase Superfamily: Thymidylate synthase/dCMP hydroxymethylase Family: Thymidylate synthase/dCMP hydroxymethylase Phyre2 PDB 1mcv chain I Region: 13 - 32 Aligned: 20 Modelled: 20 Confidence: 23.1% Identity: 45% Fold: Knottins (small inhibitors, toxins, lectins) Superfamily: Plant inhibitors of proteinases and amylases Family: Plant inhibitors of proteinases and amylases Phyre2 PDB 1mcv chain I Region: 13 - 32 Aligned: 20 Modelled: 20 Confidence: 23.1% Identity: 45% PDB header:hydrolase Chain: I: PDB Molecule:hei-toe i; PDBTitle: crystal structure analysis of a hybrid squash inhibitor in2 complex with porcine pancreatic elastase Phyre2 1 c2l6pA_ 2 c3luuA_ 3 c2fb1A_ 4 c2l6nA_ 5 c4i62A_ 6 c2yyhC_ 7 d1h9hi_ 8 c3uv1B_ 9 c3i9xA_ 10 c2fmlB_ 11 c2m2qA_ 12 c1hw4A_ 13 c3egyX_ 14 d2fmla2 15 c5t3pB_ 16 c5cw9A_ 17 c6btmB_ 18 d1hvya_ 19 d1mcvi_ 20 c1mcvI_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99