1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	A	V	V	I	T	K	H	G	D	P	S	V	L	Q	V	R	Q	R	P	D	P	P	P	P	G	P	G	Q	L	R	V	A	V	R	A	A	G	V	N	F	A	D	H	L	A	R	V	G	L	Y	P	D	A	P	K	L	P	A
Secondary structure
SS confidence
Disorder		?																					?																																	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	V	G	Y	E	V	A	G	T	V	E	A	V	G	D	G	V	D	P	N	R	V	G	E	R	V	L	A	G	T	R	F	G	G	Y	C	E	I	V	N	V	A	A	T	D	S	V	V	L	P	D	A	L	S	F	E	Q	G	A	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	P	V	N	Y	A	T	A	W	A	A	L	H	G	Y	G	S	L	R	A	G	E	R	V	L	I	H	A	A	A	G	G	V	G	I	A	A	V	Q	F	A	K	A	A	K	A	E	V	H	G	T	A	S	P	Q	K	H	Q	K	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	E	F	G	V	D	R	A	I	D	Y	R	R	D	G	W	W	Q	G	L	G	P	Y	D	V	V	L	D	A	L	G	G	T	S	L	R	R	S	Y	T	L	L	R	P	G	G	R	L	V	G	Y	G	I	S	N	M	Q	H	G	E
Secondary structure
SS confidence
Disorder																																																								?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		K	R	S	M	R	R	V	A	P	H	A	L	S	M	L	R	G	F	N	L	M	K	Q	L	E	E	S	K	T	V	I	G	L	N	M	L	R	L	W	D	D	R	R	T	L	E	P	W	I	A	P	L	T	K	A	L	N	D	G	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?					?	?	?	?	?	?	?	?	?		?												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.
Sequence		I	L	P	I	V	H	A	I	V	P	F	A	E	A	P	E	A	H	R	I	L	A	A	R	E	N	V	D	K	V	V	L	V	P
Secondary structure
SS confidence
Disorder																								?		?								?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 11%) Alpha helix ( 33%) Beta strand ( 27%) TM helix ( 5%) (View membrane topology prediction)

Rank Aligned region

PDB 2j8z chain A Region: 1 - 333 Aligned: 318 Modelled: 319 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:quinone oxidoreductase; PDBTitle: crystal structure of human p53 inducible oxidoreductase (2 tp53i3,pig3) Phyre2 PDB 3qwb chain C Region: 1 - 334 Aligned: 314 Modelled: 317 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: C: PDB Molecule:probable quinone oxidoreductase; PDBTitle: crystal structure of saccharomyces cerevisiae zeta-crystallin-like2 quinone oxidoreductase zta1 complexed with nadph Phyre2 PDB 3krt chain C Region: 1 - 333 Aligned: 330 Modelled: 333 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: C: PDB Molecule:crotonyl coa reductase; PDBTitle: crystal structure of putative crotonyl coa reductase from streptomyces2 coelicolor a3(2) Phyre2 PDB 4gi2 chain B Region: 1 - 334 Aligned: 333 Modelled: 334 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: B: PDB Molecule:crotonyl-coa carboxylase/reductase; PDBTitle: crotonyl-coa carboxylase/reductase Phyre2 PDB 1wly chain A Region: 1 - 334 Aligned: 310 Modelled: 319 Confidence: 100.0% Identity: 25% PDB header:oxidoreductase Chain: A: PDB Molecule:2-haloacrylate reductase; PDBTitle: crystal structure of 2-haloacrylate reductase Phyre2 PDB 4rvs chain A Region: 1 - 334 Aligned: 315 Modelled: 318 Confidence: 100.0% Identity: 33% PDB header:electron transport Chain: A: PDB Molecule:probable quinone reductase qor (nadph:quinone reductase) PDBTitle: the native structure of mycobacterial quinone oxidoreductase rv154c. Phyre2 PDB 3gms chain A Region: 1 - 334 Aligned: 317 Modelled: 318 Confidence: 100.0% Identity: 21% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative nadph:quinone reductase; PDBTitle: crystal structure of putative nadph:quinone reductase from bacillus2 thuringiensis Phyre2 PDB 3jyn chain A Region: 1 - 334 Aligned: 316 Modelled: 318 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: A: PDB Molecule:quinone oxidoreductase; PDBTitle: crystal structures of pseudomonas syringae pv. tomato dc30002 quinone oxidoreductase complexed with nadph Phyre2 PDB 2eih chain A Region: 1 - 333 Aligned: 332 Modelled: 333 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:alcohol dehydrogenase; PDBTitle: crystal structure of nad-dependent alcohol dehydrogenase Phyre2 PDB 4y0k chain A Region: 1 - 334 Aligned: 331 Modelled: 333 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: A: PDB Molecule:ante; PDBTitle: structure of crotonyl-coa carboxylase/reductase ante in complex with2 nadp Phyre2 PDB 1r37 chain B Region: 1 - 334 Aligned: 331 Modelled: 334 Confidence: 100.0% Identity: 16% PDB header:oxidoreductase Chain: B: PDB Molecule:nad-dependent alcohol dehydrogenase; PDBTitle: alcohol dehydrogenase from sulfolobus solfataricus2 complexed with nad(h) and 2-ethoxyethanol Phyre2 PDB 4j6f chain B Region: 1 - 334 Aligned: 333 Modelled: 332 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:putative alcohol dehydrogenase; PDBTitle: crystal structure of putative alcohol dehydrogenase from sinorhizobium2 meliloti 1021, nysgrc-target 012230 Phyre2 PDB 1qor chain A Region: 2 - 334 Aligned: 315 Modelled: 317 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: A: PDB Molecule:quinone oxidoreductase; PDBTitle: crystal structure of escherichia coli quinone oxidoreductase complexed2 with nadph Phyre2 PDB 2vcy chain A Region: 1 - 333 Aligned: 317 Modelled: 318 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:trans-2-enoyl-coa reductase; PDBTitle: crystal structure of 2-enoyl thioester reductase of human fas ii Phyre2 PDB 3uog chain B Region: 1 - 333 Aligned: 312 Modelled: 314 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: B: PDB Molecule:alcohol dehydrogenase; PDBTitle: crystal structure of putative alcohol dehydrogenase from sinorhizobium2 meliloti 1021 Phyre2 PDB 2xaa chain C Region: 1 - 334 Aligned: 329 Modelled: 334 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: C: PDB Molecule:secondary alcohol dehydrogenase; PDBTitle: alcohol dehydrogenase adh-'a' from rhodococcus ruber dsm2 44541 at ph 8.5 in complex with nad and butane-1,4-diol Phyre2 PDB 3pi7 chain A Region: 1 - 334 Aligned: 315 Modelled: 317 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: A: PDB Molecule:nadh oxidoreductase; PDBTitle: crystal structure of a putative nadph:quinone reductase (mll3093) from2 mesorhizobium loti at 1.71 a resolution Phyre2 PDB 2hcy chain D Region: 1 - 334 Aligned: 330 Modelled: 334 Confidence: 100.0% Identity: 16% PDB header:oxidoreductase Chain: D: PDB Molecule:alcohol dehydrogenase 1; PDBTitle: yeast alcohol dehydrogenase i, saccharomyces cerevisiae fermentative2 enzyme Phyre2 PDB 2c0c chain B Region: 1 - 334 Aligned: 323 Modelled: 334 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:zinc binding alcohol dehydrogenase, domain containing 2; PDBTitle: structure of the mgc45594 gene product Phyre2 PDB 4a2c chain B Region: 1 - 334 Aligned: 325 Modelled: 334 Confidence: 100.0% Identity: 16% PDB header:oxidoreductase Chain: B: PDB Molecule:galactitol-1-phosphate 5-dehydrogenase; PDBTitle: crystal structure of galactitol-1-phosphate dehydrogenase from2 escherichia coli Phyre2 1 c2j8zA_ 2 c3qwbC_ 3 c3krtC_ 4 c4gi2B_ 5 c1wlyA_ 6 c4rvsA_ 7 c3gmsA_ 8 c3jynA_ 9 c2eihA_ 10 c4y0kA_ 11 c1r37B_ 12 c4j6fB_ 13 c1qorA_ 14 c2vcyA_ 15 c3uogB_ 16 c2xaaC_ 17 c3pi7A_ 18 c2hcyD_ 19 c2c0cB_ 20 c4a2cB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166