1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	G	R	K	F	S	F	E	V	T	K	T	S	S	A	P	A	A	T	L	F	R	L	V	T	D	G	G	N	W	A	T	W	A	K	P	I	V	A	Q	S	S	W	A	R	R	G	D	P	A	P	G	G	I	G	A	I	R	K
Secondary structure
SS confidence
Disorder		?	?	?	?																																									?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	G	M	W	P	V	F	V	Q	E	E	T	V	E	Y	E	Q	D	R	R	H	V	Y	K	L	V	G	A	R	T	P	V	Q	D	Y	F	G	E	V	V	L	T	P	N	A	S	G	G	T	D	L	R	W	S	G	S	F	T	E	K
Secondary structure
SS confidence
Disorder																												?	?																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.
Sequence		V	R	G	T	G	P	V	M	R	A	A	L	G	G	A	V	R	F	F	A	G	Q	L	V	K	A	A	E	R	E	A	V	R	R
Secondary structure
SS confidence
Disorder				?																											?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 12%) Alpha helix ( 28%) Beta strand ( 45%)

Rank Aligned region

PDB 4xrw chain A Region: 5 - 153 Aligned: 145 Modelled: 149 Confidence: 99.9% Identity: 18% PDB header:lyase Chain: A: PDB Molecule:bexl; PDBTitle: crystal structure of the di-domain aro/cyc bexl from the be-7585a2 biosynthetic pathway Phyre2 PDB 2kf2 chain A Region: 1 - 154 Aligned: 150 Modelled: 154 Confidence: 99.9% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative polyketide cyclase; PDBTitle: solution nmr structure of of streptomyces coelicolor2 polyketide cyclase sco5315. northeast structural genomics3 consortium target rr365 Phyre2 PDB 3tfz chain B Region: 5 - 152 Aligned: 146 Modelled: 148 Confidence: 99.9% Identity: 16% PDB header:biosynthetic protein Chain: B: PDB Molecule:cyclase; PDBTitle: crystal structure of zhui aromatase/cyclase from streptomcyes sp.2 r1128 Phyre2 PDB 2rer chain A domain 1 Region: 1 - 151 Aligned: 147 Modelled: 151 Confidence: 99.9% Identity: 14% Fold: TBP-like Superfamily: Bet v1-like Family: oligoketide cyclase/dehydrase-like Phyre2 PDB 4n0g chain C Region: 4 - 149 Aligned: 142 Modelled: 146 Confidence: 99.9% Identity: 9% PDB header:hydrolase/receptor Chain: C: PDB Molecule:abscisic acid receptor pyl13; PDBTitle: crystal structure of pyl13-pp2ca complex Phyre2 PDB 5z8o chain A Region: 6 - 149 Aligned: 142 Modelled: 144 Confidence: 99.9% Identity: 15% PDB header:unknown function Chain: A: PDB Molecule:cyclase/dehydrase; PDBTitle: structural of start superfamily protein msmeg_0129 from mycobacterium2 smegmatis Phyre2 PDB 4xrt chain B Region: 7 - 152 Aligned: 137 Modelled: 146 Confidence: 99.9% Identity: 22% PDB header:lyase Chain: B: PDB Molecule:stfq aromatase/cyclase; PDBTitle: crystal structure of the di-domain aro/cyc stfq from the steffimycin2 biosynthetic pathway Phyre2 PDB 2le1 chain A Region: 7 - 149 Aligned: 141 Modelled: 143 Confidence: 99.9% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of tfu_2981 from thermobifida fusca, northeast2 structural genomics consortium target tfr85a Phyre2 PDB 1t17 chain A Region: 5 - 149 Aligned: 142 Modelled: 145 Confidence: 99.8% Identity: 18% Fold: TBP-like Superfamily: Bet v1-like Family: oligoketide cyclase/dehydrase-like Phyre2 PDB 2d4r chain A domain 1 Region: 7 - 152 Aligned: 141 Modelled: 146 Confidence: 99.8% Identity: 16% Fold: TBP-like Superfamily: Bet v1-like Family: oligoketide cyclase/dehydrase-like Phyre2 PDB 3qtj chain A Region: 5 - 152 Aligned: 147 Modelled: 148 Confidence: 99.8% Identity: 14% PDB header:hormone receptor Chain: A: PDB Molecule:abscisic acid receptor pyl10; PDBTitle: crystal strcuture of aba receptor pyl10 (apo) Phyre2 PDB 3cnw chain A domain 1 Region: 7 - 148 Aligned: 134 Modelled: 142 Confidence: 99.8% Identity: 14% Fold: TBP-like Superfamily: Bet v1-like Family: Atu1531-like Phyre2 PDB 2b79 chain A domain 1 Region: 6 - 148 Aligned: 135 Modelled: 143 Confidence: 99.8% Identity: 17% Fold: TBP-like Superfamily: Bet v1-like Family: Smu440-like Phyre2 PDB 3oqu chain B Region: 4 - 153 Aligned: 149 Modelled: 150 Confidence: 99.8% Identity: 12% PDB header:hormone receptor Chain: B: PDB Molecule:abscisic acid receptor pyl9; PDBTitle: crystal structure of native abscisic acid receptor pyl9 with aba Phyre2 PDB 5vgl chain A Region: 2 - 147 Aligned: 146 Modelled: 146 Confidence: 99.8% Identity: 11% PDB header:isomerase Chain: A: PDB Molecule:lachrymatory-factor synthase; PDBTitle: crystal structure of lachrymatory factor synthase from allium cepa Phyre2 PDB 2m47 chain A Region: 4 - 151 Aligned: 142 Modelled: 148 Confidence: 99.8% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein cgl2373; PDBTitle: solution nmr structure of the polyketide_cyc-like protein cgl2372 from2 corynebacterium glutamicum, northeast structural genomics consortium3 target cgr160 Phyre2 PDB 2pcs chain A domain 1 Region: 6 - 149 Aligned: 142 Modelled: 143 Confidence: 99.8% Identity: 8% Fold: TBP-like Superfamily: Bet v1-like Family: CoxG-like Phyre2 PDB 4oic chain A Region: 5 - 151 Aligned: 147 Modelled: 147 Confidence: 99.8% Identity: 16% PDB header:hormone receptor/hydrolase Chain: A: PDB Molecule:bet v i allergen-like; PDBTitle: crystal structrual of a soluble protein Phyre2 PDB 5ujv chain A Region: 4 - 151 Aligned: 148 Modelled: 148 Confidence: 99.8% Identity: 16% PDB header:abscisic acid binding protein Chain: A: PDB Molecule:pyr1; PDBTitle: crystal structure of fepyr1 in complex with abscisic acid Phyre2 PDB 5wox chain A Region: 5 - 148 Aligned: 138 Modelled: 143 Confidence: 99.8% Identity: 14% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: nmr solution structure of kany protein (ms6282) using two 4d-spectra Phyre2 1 c4xrwA_ 2 c2kf2A_ 3 c3tfzB_ 4 d2rera1 5 c4n0gC_ 6 c5z8oA_ 7 c4xrtB_ 8 c2le1A_ 9 d1t17a_ 10 d2d4ra1 11 c3qtjA_ 12 d3cnwa1 13 d2b79a1 14 c3oquB_ 15 c5vglA_ 16 c2m47A_ 17 d2pcsa1 18 c4oicA_ 19 c5ujvA_ 20 c5woxA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103