1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	F	P	R	W	P	Q	Q	A	H	N	H	E	V	S	R	A	D	T	V	S	V	P	R	A	P	T	Q	A	E	V	A	A	V	L	R	I	M	T	P	L	R	K	V	I	K	P	K	V	Y	G	I	E	N	V	P	T	E	R	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?				?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	L	V	G	N	H	N	T	L	G	L	V	D	A	P	L	L	A	A	E	L	W	E	R	G	R	I	V	R	S	L	G	D	H	A	H	F	K	I	P	G	W	R	D	A	L	T	R	T	G	V	V	E	G	T	R	E	I	T	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	L	M	R	R	G	E	L	V	M	V	F	P	G	G	A	R	E	V	N	K	R	K	N	E	R	Y	K	L	V	W	K	N	R	L	G	F	A	R	L	A	I	Q	H	G	Y	P	I	V	P	F	A	S	V	G	A	E	H	G	I
Secondary structure
SS confidence
Disorder																					?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	I	V	L	D	N	E	S	P	L	L	A	P	V	Q	F	L	A	E	K	L	L	G	T	K	D	G	P	A	L	V	R	G	V	G	L	T	P	V	P	R	P	E	R	Q	Y	Y	W	F	G	E	P	I	D	T	T	E	F	M	G
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?	?	?	?	?		?			?	?													?		?	?																					?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.
Sequence		Q	Q	A	D	D	N	A	A	R	R	V	R	E	R	A	A	A	A	I	E	H	G	I	E	L	M	L	A	E	R	A	A	D	P	N	R	S	L	V	G	R	L	L	R	S	D	A
Secondary structure
SS confidence
Disorder		?	?	?																											?	?			?										?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 17%) Alpha helix ( 36%) Beta strand ( 19%) TM helix ( 13%) (View membrane topology prediction)

Rank Aligned region

PDB 5kym chain A Region: 46 - 269 Aligned: 171 Modelled: 191 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:1-acyl-sn-glycerol-3-phosphate acyltransferase; PDBTitle: crystal structure of the 1-acyl-sn-glycerophosphate (lpa)2 acyltransferase, plsc, from thermotoga maritima Phyre2 PDB 5f34 chain A Region: 46 - 265 Aligned: 161 Modelled: 175 Confidence: 99.2% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol mannoside acyltransferase; PDBTitle: crystal structure of membrane associated pata from mycobacterium2 smegmatis in complex with s-hexadecyl coenzyme a - p21 space group Phyre2 PDB 5knk chain B Region: 47 - 265 Aligned: 161 Modelled: 175 Confidence: 98.9% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:lipid a biosynthesis lauroyl acyltransferase; PDBTitle: lipid a secondary acyltransferase lpxm from acinetobacter baumannii2 with catalytic residue substitution (e127a) Phyre2 PDB 1iuq chain A Region: 60 - 269 Aligned: 173 Modelled: 181 Confidence: 98.0% Identity: 18% Fold: Glycerol-3-phosphate (1)-acyltransferase Superfamily: Glycerol-3-phosphate (1)-acyltransferase Family: Glycerol-3-phosphate (1)-acyltransferase Phyre2 PDB 2dp3 chain A Region: 159 - 265 Aligned: 91 Modelled: 93 Confidence: 52.0% Identity: 13% PDB header:isomerase Chain: A: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of a double mutant (c202a/a198v) of triosephosphate2 isomerase from giardia lamblia Phyre2 PDB 1ttj chain A Region: 159 - 265 Aligned: 89 Modelled: 91 Confidence: 44.8% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Triosephosphate isomerase (TIM) Family: Triosephosphate isomerase (TIM) Phyre2 PDB 3qst chain A Region: 159 - 265 Aligned: 89 Modelled: 91 Confidence: 44.5% Identity: 12% PDB header:isomerase Chain: A: PDB Molecule:triosephosphate isomerase, putative; PDBTitle: crystal structure of trichomonas vaginalis triosephosphate isomerase2 tvag_096350 gene (val-45 variant) Phyre2 PDB 4ohq chain B Region: 159 - 265 Aligned: 87 Modelled: 89 Confidence: 42.3% Identity: 13% PDB header:isomerase Chain: B: PDB Molecule:triosephosphate isomerase, chloroplastic; PDBTitle: crystal structure of chloroplast triose phosphate isomerase from2 arabidopsis thaliana Phyre2 PDB 4x22 chain A Region: 158 - 261 Aligned: 84 Modelled: 88 Confidence: 41.5% Identity: 13% PDB header:isomerase Chain: A: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of leptospira interrogans triosephosphate isomerase2 (litim) Phyre2 PDB 4mkn chain A Region: 159 - 265 Aligned: 87 Modelled: 89 Confidence: 40.6% Identity: 13% PDB header:isomerase Chain: A: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of chloroplastic triosephosphate isomerase from2 chlamydomonas reinhardtii at 1.1 a of resolution Phyre2 PDB 5eyw chain B Region: 159 - 265 Aligned: 87 Modelled: 89 Confidence: 40.0% Identity: 11% PDB header:isomerase Chain: B: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of litopenaeus vannamei triosephosphate isomerase2 complexed with 2-phosphoglycolic acid Phyre2 PDB 1np7 chain A domain 2 Region: 161 - 235 Aligned: 65 Modelled: 75 Confidence: 37.6% Identity: 11% Fold: Cryptochrome/photolyase, N-terminal domain Superfamily: Cryptochrome/photolyase, N-terminal domain Family: Cryptochrome/photolyase, N-terminal domain Phyre2 PDB 4wbd chain A Region: 101 - 178 Aligned: 72 Modelled: 73 Confidence: 37.0% Identity: 17% PDB header:ligase Chain: A: PDB Molecule:bshc; PDBTitle: the crystal structure of bshc from bacillus subtilis complexed with2 citrate and adp Phyre2 PDB 1sux chain A Region: 159 - 265 Aligned: 89 Modelled: 91 Confidence: 36.2% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Triosephosphate isomerase (TIM) Family: Triosephosphate isomerase (TIM) Phyre2 PDB 1yya chain A Region: 159 - 265 Aligned: 89 Modelled: 91 Confidence: 35.5% Identity: 19% PDB header:isomerase Chain: A: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of tt0473, putative triosephosphate isomerase from2 thermus thermophilus hb8 Phyre2 PDB 5upr chain A Region: 159 - 265 Aligned: 90 Modelled: 92 Confidence: 35.2% Identity: 8% PDB header:isomerase Chain: A: PDB Molecule:triosephosphate isomerase; PDBTitle: x-ray structure of a putative triosephosphate isomerase from2 toxoplasma gondii me49 Phyre2 PDB 1m6j chain A Region: 168 - 265 Aligned: 80 Modelled: 82 Confidence: 33.7% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Triosephosphate isomerase (TIM) Family: Triosephosphate isomerase (TIM) Phyre2 PDB 4y8f chain A Region: 159 - 265 Aligned: 89 Modelled: 91 Confidence: 33.6% Identity: 16% PDB header:isomerase Chain: A: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of triosephosphate isomerase from clostridium2 perfringens Phyre2 PDB 1zgg chain A Region: 230 - 271 Aligned: 40 Modelled: 42 Confidence: 32.5% Identity: 10% PDB header:hydrolase Chain: A: PDB Molecule:putative low molecular weight protein-tyrosine- PDBTitle: solution structure of a low molecular weight protein2 tyrosine phosphatase from bacillus subtilis Phyre2 PDB 4eti chain A Region: 230 - 271 Aligned: 40 Modelled: 42 Confidence: 32.5% Identity: 10% PDB header:hydrolase Chain: A: PDB Molecule:low molecular weight protein-tyrosine-phosphatase ywle; PDBTitle: crystal structure of ywle from bacillus subtilis Phyre2 1 c5kymA_ 2 c5f34A_ 3 c5knkB_ 4 d1iuqa_ 5 c2dp3A_ 6 d1ttja_ 7 c3qstA_ 8 c4ohqB_ 9 c4x22A_ 10 c4mknA_ 11 c5eywB_ 12 d1np7a2 13 c4wbdA_ 14 d1suxa_ 15 c1yyaA_ 16 c5uprA_ 17 d1m6ja_ 18 c4y8fA_ 19 c1zggA_ 20 c4etiA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64