1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	A	D	V	P	L	D	A	Q	E	R	L	E	L	C	D	L	L	E	E	L	G	P	A	V	A	T	L	I	E	G	W	T	A	H	D	L	A	A	H	I	V	L	R	E	R	D	L	V	A	G	L	C	I	V	L	P	G	P	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?																																											?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	R	F	A	E	R	R	R	A	R	L	A	Q	S	K	D	F	T	W	L	V	A	R	I	R	S	G	P	P	M	G	F	F	R	I	G	W	V	R	T	L	A	N	L	N	E	F	F	V	H	H	E	D	V	R	R	A	S	G	R
Secondary structure
SS confidence
Disorder			?										?	?	?															?	?				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	P	R	S	L	T	P	E	M	D	A	A	L	W	R	N	V	R	R	G	S	H	F	L	S	R	R	L	H	G	C	G	L	E	I	E	W	V	G	T	G	K	R	V	R	V	R	S	G	E	P	T	A	R	L	T	G	P	P	G
Secondary structure
SS confidence
Disorder			?																	?		?	?	?	?	?	?	?	?	?	?	?										?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.
Sequence		E	L	L	L	Y	V	F	G	R	R	A	V	A	R	V	E	V	S	G	P	L	E	A	I	A	A	V	H	R	T	H	F	G	M
Secondary structure
SS confidence
Disorder																?														?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 18%) Alpha helix ( 54%) Beta strand ( 7%)

Rank Aligned region

PDB 2nsf chain A Region: 4 - 200 Aligned: 192 Modelled: 197 Confidence: 100.0% Identity: 15% PDB header:isomerase Chain: A: PDB Molecule:hypothetical protein cgl3021; PDBTitle: crystal structure of the mycothiol-dependent maleylpyruvate isomerase Phyre2 PDB 2nsf chain A domain 1 Region: 1 - 120 Aligned: 120 Modelled: 120 Confidence: 99.8% Identity: 15% Fold: DinB/YfiT-like putative metalloenzymes Superfamily: DinB/YfiT-like putative metalloenzymes Family: Maleylpyruvate isomerase-like Phyre2 PDB 5cog chain B Region: 1 - 86 Aligned: 86 Modelled: 86 Confidence: 97.7% Identity: 7% PDB header:unknown function Chain: B: PDB Molecule:irc4; PDBTitle: crystal structure of yeast irc4 Phyre2 PDB 2nsf chain A domain 2 Region: 125 - 200 Aligned: 73 Modelled: 76 Confidence: 97.6% Identity: 15% Fold: SCP-like Superfamily: SCP-like Family: Micothiol-dependent maleylpyruvate isomerase C-terminal domain-like Phyre2 PDB 5civ chain A Region: 4 - 87 Aligned: 84 Modelled: 84 Confidence: 97.2% Identity: 12% PDB header:unknown function Chain: A: PDB Molecule:sibling bacteriocin; PDBTitle: sibling lethal factor precursor - dfsb Phyre2 PDB 2yqy chain B Region: 4 - 118 Aligned: 114 Modelled: 114 Confidence: 97.2% Identity: 19% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein ttha0303; PDBTitle: crystal structure of tt2238, a four-helix bundle protein Phyre2 PDB 4n6c chain B Region: 4 - 87 Aligned: 84 Modelled: 83 Confidence: 96.8% Identity: 8% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the b1rzq2 protein from streptococcus pneumoniae.2 northeast structural genomics consortium (nesg) target spr36. Phyre2 PDB 1rxq chain A Region: 1 - 86 Aligned: 86 Modelled: 86 Confidence: 96.4% Identity: 7% Fold: DinB/YfiT-like putative metalloenzymes Superfamily: DinB/YfiT-like putative metalloenzymes Family: YfiT-like putative metal-dependent hydrolases Phyre2 PDB 2rd9 chain C Region: 4 - 86 Aligned: 83 Modelled: 83 Confidence: 96.1% Identity: 12% PDB header:hydrolase Chain: C: PDB Molecule:bh0186 protein; PDBTitle: crystal structure of a putative yfit-like metal-dependent hydrolase2 (bh0186) from bacillus halodurans c-125 at 2.30 a resolution Phyre2 PDB 5cof chain A Region: 4 - 87 Aligned: 84 Modelled: 84 Confidence: 95.4% Identity: 13% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterised protein q1r1x2 from escherichia2 coli uti89 Phyre2 PDB 6anr chain A Region: 4 - 87 Aligned: 84 Modelled: 84 Confidence: 93.7% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:colibactin self-protection protein clbs; PDBTitle: crystal structure of a self resistance protein clbs from colibactin2 biosynthetic gene cluster Phyre2 PDB 5cqv chain B Region: 4 - 87 Aligned: 84 Modelled: 84 Confidence: 91.4% Identity: 11% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein q8dwv2 from streptococcus2 agalactiae Phyre2 PDB 1ikt chain A Region: 153 - 209 Aligned: 57 Modelled: 57 Confidence: 90.2% Identity: 12% Fold: SCP-like Superfamily: SCP-like Family: Sterol carrier protein, SCP Phyre2 PDB 3bdq chain B Region: 168 - 209 Aligned: 42 Modelled: 42 Confidence: 89.6% Identity: 19% PDB header:lipid transport Chain: B: PDB Molecule:sterol carrier protein 2-like 2; PDBTitle: room tempreture crystal structure of sterol carrier protein-2 2 like-2 Phyre2 PDB 2cfu chain A domain 1 Region: 130 - 209 Aligned: 80 Modelled: 80 Confidence: 89.3% Identity: 13% Fold: SCP-like Superfamily: SCP-like Family: Alkylsulfatase C-terminal domain-like Phyre2 PDB 6iz2 chain A Region: 1 - 125 Aligned: 123 Modelled: 123 Confidence: 89.3% Identity: 15% PDB header:unknown function Chain: A: PDB Molecule:dinb/yfit family protein; PDBTitle: crystal structure of dinb/yfit protein dr0053 from d. radiodurans r1 Phyre2 PDB 1pz4 chain A Region: 153 - 209 Aligned: 57 Modelled: 57 Confidence: 86.3% Identity: 16% Fold: SCP-like Superfamily: SCP-like Family: Sterol carrier protein, SCP Phyre2 PDB 6h6p chain A Region: 124 - 209 Aligned: 86 Modelled: 86 Confidence: 86.3% Identity: 17% PDB header:lipid binding protein Chain: A: PDB Molecule:ubiquinone biosynthesis protein ubij; PDBTitle: ubij-scp2 ubiquinone synthesis protein Phyre2 PDB 2hkv chain A domain 1 Region: 3 - 111 Aligned: 109 Modelled: 109 Confidence: 86.1% Identity: 9% Fold: DinB/YfiT-like putative metalloenzymes Superfamily: DinB/YfiT-like putative metalloenzymes Family: DinB-like Phyre2 PDB 1c44 chain A Region: 153 - 209 Aligned: 57 Modelled: 57 Confidence: 81.6% Identity: 11% Fold: SCP-like Superfamily: SCP-like Family: Sterol carrier protein, SCP Phyre2 1 c2nsfA_ 2 d2nsfa1 3 c5cogB_ 4 d2nsfa2 5 c5civA_ 6 c2yqyB_ 7 c4n6cB_ 8 d1rxqa_ 9 c2rd9C_ 10 c5cofA_ 11 c6anrA_ 12 c5cqvB_ 13 d1ikta_ 14 c3bdqB_ 15 d2cfua1 16 c6iz2A_ 17 d1pz4a_ 18 c6h6pA_ 19 d2hkva1 20 d1c44a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49