1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	T	A	L	P	A	R	G	E	V	W	W	C	E	M	A	E	I	G	R	R	P	V	V	V	L	S	R	D	A	A	I	P	R	L	R	R	A	L	V	A	P	C	T	T	T	I	R	G	L	A	S	E	V	V	L	E	P	G	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?																									?	?	?	?																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.
Sequence		D	P	I	P	R	R	S	A	V	N	L	D	S	V	E	S	V	S	V	A	V	L	V	N	R	L	G	R	L	A	D	I	R	M	R	A	I	C	T	A	L	E	V	A	V	D	C	S	R
Secondary structure
SS confidence
Disorder		?																																													?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 24%) Beta strand ( 30%)

Rank Aligned region

PDB 1ub4 chain A Region: 2 - 106 Aligned: 100 Modelled: 105 Confidence: 100.0% Identity: 29% Fold: SH3-like barrel Superfamily: Cell growth inhibitor/plasmid maintenance toxic component Family: Kid/PemK Phyre2 PDB 5xe3 chain B Region: 3 - 107 Aligned: 96 Modelled: 96 Confidence: 100.0% Identity: 26% PDB header:hydrolase/antitoxin Chain: B: PDB Molecule:endoribonuclease mazf4; PDBTitle: endoribonuclease in complex with its cognate antitoxin from2 mycobacterial species Phyre2 PDB 5wyg chain C Region: 3 - 107 Aligned: 102 Modelled: 105 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: C: PDB Molecule:probable endoribonuclease mazf7; PDBTitle: the crystal structure of the apo form of mtb mazf Phyre2 PDB 4mzp chain C Region: 6 - 108 Aligned: 103 Modelled: 103 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: C: PDB Molecule:mazf mrna interferase; PDBTitle: mazf from s. aureus crystal form iii, c2221, 2.7 a Phyre2 PDB 1ne8 chain A Region: 4 - 107 Aligned: 104 Modelled: 104 Confidence: 100.0% Identity: 25% Fold: SH3-like barrel Superfamily: Cell growth inhibitor/plasmid maintenance toxic component Family: Kid/PemK Phyre2 PDB 5hk3 chain B Region: 6 - 107 Aligned: 98 Modelled: 102 Confidence: 100.0% Identity: 27% PDB header:hydrolase/dna Chain: B: PDB Molecule:endoribonuclease mazf6; PDBTitle: crystal structure of m. tuberculosis mazf-mt3 t52d-f62d mutant in2 complex with dna Phyre2 PDB 1m1f chain A Region: 6 - 105 Aligned: 98 Modelled: 99 Confidence: 99.9% Identity: 28% Fold: SH3-like barrel Superfamily: Cell growth inhibitor/plasmid maintenance toxic component Family: Kid/PemK Phyre2 PDB 5hjz chain A Region: 6 - 107 Aligned: 102 Modelled: 101 Confidence: 99.9% Identity: 25% PDB header:hydrolase/rna Chain: A: PDB Molecule:endoribonuclease mazf9; PDBTitle: structure of m. tuberculosis mazf-mt1 (rv2801c) in complex with rna Phyre2 PDB 5cca chain A Region: 19 - 107 Aligned: 88 Modelled: 89 Confidence: 99.9% Identity: 34% PDB header:hydrolase Chain: A: PDB Molecule:endoribonuclease mazf3; PDBTitle: crystal structure of mtb toxin Phyre2 PDB 3jrz chain A Region: 18 - 105 Aligned: 82 Modelled: 88 Confidence: 95.1% Identity: 17% PDB header:toxin Chain: A: PDB Molecule:ccdb; PDBTitle: ccdbvfi-formii-ph5.6 Phyre2 PDB 3vub chain A Region: 11 - 105 Aligned: 93 Modelled: 95 Confidence: 95.1% Identity: 18% Fold: SH3-like barrel Superfamily: Cell growth inhibitor/plasmid maintenance toxic component Family: CcdB Phyre2 PDB 2l89 chain A Region: 8 - 106 Aligned: 87 Modelled: 99 Confidence: 71.8% Identity: 18% PDB header:protein binding Chain: A: PDB Molecule:pwwp domain-containing protein 1; PDBTitle: solution structure of pdp1 pwwp domain reveals its unique binding2 sites for methylated h4k20 and dna Phyre2 PDB 1h3z chain A Region: 1 - 106 Aligned: 94 Modelled: 104 Confidence: 71.5% Identity: 13% Fold: SH3-like barrel Superfamily: Tudor/PWWP/MBT Family: PWWP domain Phyre2 PDB 3llr chain A Region: 8 - 104 Aligned: 82 Modelled: 84 Confidence: 63.3% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:dna (cytosine-5)-methyltransferase 3a; PDBTitle: crystal structure of the pwwp domain of human dna (cytosine-5-)-2 methyltransferase 3 alpha Phyre2 PDB 5ikj chain A Region: 8 - 32 Aligned: 24 Modelled: 25 Confidence: 50.7% Identity: 25% PDB header:transcription Chain: A: PDB Molecule:cryptic loci regulator 2; PDBTitle: structure of clr2 bound to the clr1 c-terminus Phyre2 PDB 2daq chain A domain 1 Region: 8 - 33 Aligned: 26 Modelled: 26 Confidence: 41.2% Identity: 8% Fold: SH3-like barrel Superfamily: Tudor/PWWP/MBT Family: PWWP domain Phyre2 PDB 3bxp chain A Region: 1 - 26 Aligned: 26 Modelled: 23 Confidence: 35.2% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:putative lipase/esterase; PDBTitle: crystal structure of a putative carboxylesterase (lp_2923) from2 lactobacillus plantarum wcfs1 at 1.70 a resolution Phyre2 PDB 4ld6 chain A Region: 8 - 108 Aligned: 88 Modelled: 101 Confidence: 23.5% Identity: 16% PDB header:unknown function Chain: A: PDB Molecule:pwwp domain-containing protein 2b; PDBTitle: pwwp domain of human pwwp domain-containing protein 2b Phyre2 PDB 4bed chain A Region: 63 - 104 Aligned: 42 Modelled: 42 Confidence: 17.8% Identity: 21% PDB header:oxygen transport Chain: A: PDB Molecule:hemocyanin klh1; PDBTitle: keyhole limpet hemocyanin (klh): 9a cryoem structure and molecular2 model of the klh1 didecamer reveal the interfaces and intricate3 topology of the 160 functional units Phyre2 PDB 4me8 chain A Region: 4 - 20 Aligned: 17 Modelled: 17 Confidence: 16.9% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:signal peptidase i; PDBTitle: crystal structure of a signal peptidase i (ef3073) from enterococcus2 faecalis v583 at 2.27 a resolution Phyre2 1 d1ub4a_ 2 c5xe3B_ 3 c5wygC_ 4 c4mzpC_ 5 d1ne8a_ 6 c5hk3B_ 7 d1m1fa_ 8 c5hjzA_ 9 c5ccaA_ 10 c3jrzA_ 11 d3vuba_ 12 c2l89A_ 13 d1h3za_ 14 c3llrA_ 15 c5ikjA_ 16 d2daqa1 17 c3bxpA_ 18 c4ld6A_ 19 c4bedA_ 20 c4me8A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48