1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	S	S	R	Y	L	L	S	P	A	A	Q	A	H	L	E	E	I	W	D	C	T	Y	D	R	W	G	V	D	Q	A	E	Q	Y	L	R	E	L	Q	H	A	I	D	R	A	A	A	N	P	R	I	G	R	A	C	D	E	I	R	P
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.
Sequence		G	Y	R	K	L	S	A	G	S	H	T	L	F	Y	R	V	T	G	E	G	T	I	D	V	V	R	V	L	H	Q	R	M	D	V	D	R	N	L
Secondary structure
SS confidence
Disorder																																	?	?				?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 8%) Alpha helix ( 45%) Beta strand ( 28%)

Rank Aligned region

PDB 5ceg chain B Region: 1 - 97 Aligned: 96 Modelled: 97 Confidence: 99.9% Identity: 28% PDB header:toxin Chain: B: PDB Molecule:plasmid stabilization system; PDBTitle: x-ray structure of toxin/anti-toxin complex from mesorhizobium2 opportunistum Phyre2 PDB 3kxe chain B Region: 3 - 98 Aligned: 94 Modelled: 96 Confidence: 99.9% Identity: 43% PDB header:protein binding Chain: B: PDB Molecule:toxin protein pare-1; PDBTitle: a conserved mode of protein recognition and binding in a2 pard-pare toxin-antitoxin complex Phyre2 PDB 5cw7 chain H Region: 2 - 95 Aligned: 92 Modelled: 93 Confidence: 99.9% Identity: 21% PDB header:toxin Chain: H: PDB Molecule:plasmid stabilization protein pare; PDBTitle: crystal structure of the paaa2-pare2 antitoxin-toxin complex Phyre2 PDB 1wmi chain A domain 1 Region: 1 - 89 Aligned: 77 Modelled: 89 Confidence: 98.4% Identity: 13% Fold: RelE-like Superfamily: RelE-like Family: RelE-like Phyre2 PDB 2khe chain A Region: 1 - 89 Aligned: 81 Modelled: 89 Confidence: 98.3% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:toxin-like protein; PDBTitle: solution structure of the bacterial toxin rele from thermus2 thermophilus hb8 Phyre2 PDB 3g5o chain C Region: 1 - 89 Aligned: 78 Modelled: 89 Confidence: 98.1% Identity: 19% PDB header:toxin/antitoxin Chain: C: PDB Molecule:uncharacterized protein rv2866; PDBTitle: the crystal structure of the toxin-antitoxin complex relbe2 (rv2865-2 2866) from mycobacterium tuberculosis Phyre2 PDB 3oei chain H Region: 2 - 90 Aligned: 79 Modelled: 80 Confidence: 98.0% Identity: 16% PDB header:toxin, protein binding Chain: H: PDB Molecule:relk (toxin rv3358); PDBTitle: crystal structure of mycobacterium tuberculosis reljk (rv3357-rv3358-2 relbe3) Phyre2 PDB 2a6s chain A domain 1 Region: 3 - 90 Aligned: 78 Modelled: 88 Confidence: 97.8% Identity: 14% Fold: RelE-like Superfamily: RelE-like Family: YoeB/Txe-like Phyre2 PDB 3bpq chain D Region: 5 - 89 Aligned: 72 Modelled: 73 Confidence: 97.4% Identity: 22% PDB header:toxin Chain: D: PDB Molecule:toxin rele3; PDBTitle: crystal structure of relb-rele antitoxin-toxin complex from2 methanococcus jannaschii Phyre2 PDB 3kix chain Y Region: 2 - 89 Aligned: 76 Modelled: 76 Confidence: 96.9% Identity: 24% PDB header:ribosome Chain: Y: PDB Molecule: PDBTitle: structure of rele nuclease bound to the 70s ribosome (postcleavage2 state; part 3 of 4) Phyre2 PDB 2otr chain A Region: 2 - 92 Aligned: 84 Modelled: 91 Confidence: 95.6% Identity: 13% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein hp0892; PDBTitle: solution structure of conserved hypothetical protein hp0892 from2 helicobacter pylori Phyre2 PDB 5ja9 chain D Region: 36 - 89 Aligned: 53 Modelled: 54 Confidence: 91.8% Identity: 21% PDB header:toxin Chain: D: PDB Molecule:toxin higb-2; PDBTitle: crystal structure of the higb2 toxin in complex with nb6 Phyre2 PDB 1z8m chain A domain 1 Region: 2 - 87 Aligned: 76 Modelled: 86 Confidence: 87.9% Identity: 16% Fold: RelE-like Superfamily: RelE-like Family: RelE-like Phyre2 PDB 4q2u chain H Region: 2 - 87 Aligned: 76 Modelled: 86 Confidence: 38.7% Identity: 16% PDB header:toxin/toxin repressor Chain: H: PDB Molecule:mrna interferase yafq; PDBTitle: crystal structure of the e. coli dinj-yafq toxin-antitoxin complex Phyre2 PDB 2apn chain A Region: 1 - 20 Aligned: 20 Modelled: 20 Confidence: 38.5% Identity: 10% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein hi1723; PDBTitle: hi1723 solution structure Phyre2 PDB 2dbh chain A Region: 9 - 52 Aligned: 43 Modelled: 44 Confidence: 37.9% Identity: 14% PDB header:signaling protein Chain: A: PDB Molecule:tumor necrosis factor receptor superfamily PDBTitle: solution structure of the carboxyl-terminal card-like2 domain in human tnfr-related death receptor-6 Phyre2 PDB 4mct chain D Region: 26 - 89 Aligned: 63 Modelled: 64 Confidence: 18.9% Identity: 13% PDB header:toxin Chain: D: PDB Molecule:killer protein; PDBTitle: p. vulgaris higba structure, crystal form 1 Phyre2 PDB 3w8h chain B Region: 10 - 44 Aligned: 34 Modelled: 35 Confidence: 16.7% Identity: 15% PDB header:protein binding/transferase Chain: B: PDB Molecule:serine/threonine-protein kinase 25; PDBTitle: crystal structure of ccm3 in complex with the c-terminal regulatory2 domain of stk25 Phyre2 PDB 1pmm chain A Region: 26 - 49 Aligned: 24 Modelled: 24 Confidence: 15.1% Identity: 21% Fold: PLP-dependent transferase-like Superfamily: PLP-dependent transferases Family: Pyridoxal-dependent decarboxylase Phyre2 PDB 1egx chain A Region: 27 - 46 Aligned: 20 Modelled: 20 Confidence: 13.9% Identity: 15% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 1 c5cegB_ 2 c3kxeB_ 3 c5cw7H_ 4 d1wmia1 5 c2kheA_ 6 c3g5oC_ 7 c3oeiH_ 8 d2a6sa1 9 c3bpqD_ 10 c3kixy_ 11 c2otrA_ 12 c5ja9D_ 13 d1z8ma1 14 c4q2uH_ 15 c2apnA_ 16 c2dbhA_ 17 c4mctD_ 18 c3w8hB_ 19 d1pmma_ 20 d1egxa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47