1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	N	S	P	L	V	V	G	F	L	A	C	F	T	L	I	A	A	I	G	A	Q	N	A	F	V	L	R	Q	G	I	Q	R	E	H	V	L	P	V	V	A	L	C	T	V	S	D	I	V	L	I	A	A	G	I	A	G	F	G	A
Secondary structure
SS confidence
Disorder		?	?																													?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	I	G	A	H	P	R	A	L	N	V	V	K	F	G	G	A	A	F	L	I	G	Y	G	L	L	A	A	R	R	A	W	R	P	V	A	L	I	P	S	G	A	T	P	V	R	L	A	E	V	L	V	T	C	A	A	F	T	F	L
Secondary structure
SS confidence
Disorder																															?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	P	H	V	Y	L	D	T	V	V	L	L	G	A	L	A	N	E	H	S	D	Q	R	W	L	F	G	L	G	A	V	T	A	S	A	V	W	F	A	T	L	G	F	G	A	G	R	L	R	G	L	F	T	N	P	G	S	W	R	I
Secondary structure
SS confidence
Disorder															?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.
Sequence		L	D	G	L	I	A	V	M	M	V	A	L	G	I	S	L	T	V	T
Secondary structure
SS confidence
Disorder																			?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 82%) Beta strand ( 0%) TM helix ( 59%) (View membrane topology prediction)

Rank Aligned region

PDB 5vkv chain A Region: 1 - 199 Aligned: 196 Modelled: 199 Confidence: 99.2% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c-type biogenesis protein ccda; PDBTitle: solution nmr structure of the membrane electron transporter ccda Phyre2 PDB 2n4x chain A Region: 8 - 199 Aligned: 180 Modelled: 192 Confidence: 95.0% Identity: 8% PDB header:membrane protein Chain: A: PDB Molecule:cytochrome c-type biogenesis protein (ccda); PDBTitle: structure of the transmembrane electron transporter ccda Phyre2 PDB 4zp0 chain A Region: 5 - 199 Aligned: 195 Modelled: 195 Confidence: 31.7% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:multidrug transporter mdfa; PDBTitle: crystal structure of e. coli multidrug transporter mdfa in complex2 with deoxycholate Phyre2 PDB 4x5m chain B Region: 1 - 99 Aligned: 93 Modelled: 99 Confidence: 29.7% Identity: 17% PDB header:transport protein Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of semisweet in the inward-open conformation Phyre2 PDB 5xyv chain C Region: 108 - 122 Aligned: 15 Modelled: 15 Confidence: 24.4% Identity: 7% PDB header:protein binding Chain: C: PDB Molecule:protein deadlock; PDBTitle: crystal structure of drosophila melanogaster rhino chromoshadow domain2 in complex with deadlock n-terminal domain Phyre2 PDB 2knc chain A Region: 66 - 103 Aligned: 38 Modelled: 38 Confidence: 19.9% Identity: 18% PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex Phyre2 PDB 4iu8 chain A Region: 88 - 194 Aligned: 107 Modelled: 107 Confidence: 10.6% Identity: 12% PDB header:transport protein Chain: A: PDB Molecule:nitrite extrusion protein 2; PDBTitle: crystal structure of a membrane transporter (selenomethionine2 derivative) Phyre2 PDB 1pw4 chain A Region: 5 - 194 Aligned: 190 Modelled: 190 Confidence: 10.5% Identity: 9% Fold: MFS general substrate transporter Superfamily: MFS general substrate transporter Family: Glycerol-3-phosphate transporter Phyre2 PDB 1jog chain A Region: 83 - 115 Aligned: 33 Modelled: 33 Confidence: 9.6% Identity: 12% Fold: Four-helical up-and-down bundle Superfamily: Nucleotidyltransferase substrate binding subunit/domain Family: Family 1 bi-partite nucleotidyltransferase subunit Phyre2 PDB 6e9o chain A Region: 5 - 199 Aligned: 195 Modelled: 195 Confidence: 9.2% Identity: 11% PDB header:membrane protein Chain: A: PDB Molecule:d-galactonate transport; PDBTitle: e. coli d-galactonate:proton symporter mutant e133q in the outward2 substrate-bound form Phyre2 PDB 2mic chain A Region: 66 - 96 Aligned: 31 Modelled: 31 Confidence: 7.9% Identity: 3% PDB header:membrane protein Chain: A: PDB Molecule:tumor necrosis factor receptor superfamily member 16; PDBTitle: nmr structure of p75 transmembrane domain in dpc micelles Phyre2 PDB 2mic chain B Region: 66 - 96 Aligned: 31 Modelled: 31 Confidence: 7.9% Identity: 3% PDB header:membrane protein Chain: B: PDB Molecule:tumor necrosis factor receptor superfamily member 16; PDBTitle: nmr structure of p75 transmembrane domain in dpc micelles Phyre2 PDB 4iu9 chain A Region: 87 - 194 Aligned: 108 Modelled: 108 Confidence: 7.6% Identity: 12% PDB header:transport protein Chain: A: PDB Molecule:nitrite extrusion protein 2; PDBTitle: crystal structure of a membrane transporter Phyre2 PDB 2zxe chain G Region: 179 - 199 Aligned: 21 Modelled: 21 Confidence: 6.5% Identity: 19% PDB header:hydrolase/transport protein Chain: G: PDB Molecule:phospholemman-like protein; PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state Phyre2 PDB 5azd chain A Region: 21 - 173 Aligned: 148 Modelled: 153 Confidence: 6.5% Identity: 9% PDB header:transport protein Chain: A: PDB Molecule:bacteriorhodopsin; PDBTitle: crystal structure of thermophilic rhodopsin. Phyre2 PDB 2mkv chain A Region: 179 - 199 Aligned: 21 Modelled: 21 Confidence: 6.4% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:sodium/potassium-transporting atpase subunit gamma; PDBTitle: structure of the na,k-atpase regulatory protein fxyd2b in micelles Phyre2 PDB 2jp3 chain A Region: 176 - 199 Aligned: 24 Modelled: 24 Confidence: 6.0% Identity: 17% PDB header:transcription Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4; PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles Phyre2 PDB 1q90 chain G Region: 1 - 14 Aligned: 14 Modelled: 14 Confidence: 5.8% Identity: 21% Fold: Single transmembrane helix Superfamily: PetG subunit of the cytochrome b6f complex Family: PetG subunit of the cytochrome b6f complex Phyre2 PDB 1q90 chain G Region: 1 - 14 Aligned: 14 Modelled: 14 Confidence: 5.8% Identity: 21% PDB header:photosynthesis Chain: G: PDB Molecule:cytochrome b6f complex subunit petg; PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii Phyre2 PDB 1jb0 chain L Region: 66 - 130 Aligned: 65 Modelled: 65 Confidence: 5.5% Identity: 3% Fold: Photosystem I reaction center subunit XI, PsaL Superfamily: Photosystem I reaction center subunit XI, PsaL Family: Photosystem I reaction center subunit XI, PsaL Phyre2 1 c5vkvA_ 2 c2n4xA_ 3 c4zp0A_ 4 c4x5mB_ 5 c5xyvC_ 6 c2kncA_ 7 c4iu8A_ 8 d1pw4a_ 9 d1joga_ 10 c6e9oA_ 11 c2micA_ 12 c2micB_ 13 c4iu9A_ 14 c2zxeG_ 15 c5azdA_ 16 c2mkvA_ 17 c2jp3A_ 18 d1q90g_ 19 c1q90G_ 20 d1jb0l_ 21 22 23 24 25 26