1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	D	T	L	L	E	A	G	I	T	V	V	V	I	S	P	N	Q	L	K	N	L	R	G	R	Y	G	S	A	G	N	K	D	D	R	F	D	A	F	V	L	A	D	T	L	R	T	D	R	S	R	L	R	P	L	L	P	D	T	P
Secondary structure
SS confidence
Disorder		?																									?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	T	A	T	L	R	R	T	C	R	P	R	K	D	L	V	A	H	R	V	A	L	A	N	Q	L	R	A	H	L	R	V	V	F	P	G	V	V	G	L	F	A	D	L	D	S	P	I	S	L	A	F	L	T	F	L	P	R	F	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.
Sequence		C	Q	D	R	A	D	W	L	S	V	K	R	L	A	G	W	L	A	A	A	G	Y	C	G	R	A	P	R	P	A	H	R	C	P	A	R	R	H	R
Secondary structure
SS confidence
Disorder						?	?		?												?	?	?	?	?	?	?	?	?									?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 67%) Beta strand ( 3%)

Rank Aligned region

PDB 1hjr chain A Region: 3 - 51 Aligned: 49 Modelled: 49 Confidence: 68.9% Identity: 20% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: RuvC resolvase Phyre2 PDB 4ep5 chain A Region: 3 - 47 Aligned: 44 Modelled: 45 Confidence: 62.2% Identity: 32% PDB header:hydrolase Chain: A: PDB Molecule:crossover junction endodeoxyribonuclease ruvc; PDBTitle: thermus thermophilus ruvc structure Phyre2 PDB 2fi0 chain A domain 1 Region: 90 - 142 Aligned: 53 Modelled: 53 Confidence: 59.5% Identity: 21% Fold: SP0561-like Superfamily: SP0561-like Family: SP0561-like Phyre2 PDB 2ozb chain B domain 1 Region: 58 - 103 Aligned: 46 Modelled: 46 Confidence: 54.8% Identity: 11% Fold: Nop domain Superfamily: Nop domain Family: Nop domain Phyre2 PDB 1y81 chain A domain 1 Region: 2 - 16 Aligned: 15 Modelled: 15 Confidence: 53.2% Identity: 33% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 3ff4 chain A Region: 2 - 16 Aligned: 15 Modelled: 15 Confidence: 47.7% Identity: 13% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein chu_1412 Phyre2 PDB 2duw chain A Region: 2 - 16 Aligned: 15 Modelled: 15 Confidence: 42.5% Identity: 40% PDB header:ligand binding protein Chain: A: PDB Molecule:putative coa-binding protein; PDBTitle: solution structure of putative coa-binding protein of2 klebsiella pneumoniae Phyre2 PDB 2d59 chain A domain 1 Region: 2 - 16 Aligned: 15 Modelled: 15 Confidence: 41.6% Identity: 40% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 1a9x chain A domain 3 Region: 1 - 16 Aligned: 16 Modelled: 16 Confidence: 36.1% Identity: 25% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: BC N-terminal domain-like Phyre2 PDB 5xav chain B Region: 1 - 15 Aligned: 15 Modelled: 15 Confidence: 35.2% Identity: 27% PDB header:biosynthetic protein Chain: B: PDB Molecule:intracellular polyhydroxyalkanoate synthase; PDBTitle: structure of phac from chromobacterium sp. usm2 Phyre2 PDB 5t6o chain A Region: 1 - 15 Aligned: 15 Modelled: 15 Confidence: 31.2% Identity: 40% PDB header:biosynthetic protein Chain: A: PDB Molecule:poly-beta-hydroxybuterate polymerase; PDBTitle: structure of the catalytic domain of the class i polyhydroxybutyrate2 synthase from cupriavidus necator Phyre2 PDB 5o9z chain H Region: 58 - 103 Aligned: 46 Modelled: 46 Confidence: 26.4% Identity: 11% PDB header:splicing Chain: H: PDB Molecule:u4/u6 small nuclear ribonucleoprotein prp31; PDBTitle: cryo-em structure of a pre-catalytic human spliceosome primed for2 activation (b complex) Phyre2 PDB 5dot chain A Region: 1 - 16 Aligned: 16 Modelled: 16 Confidence: 25.9% Identity: 25% PDB header:ligase Chain: A: PDB Molecule:carbamoyl-phosphate synthase [ammonia], mitochondrial; PDBTitle: crystal structure of human carbamoyl phosphate synthetase i (cps1),2 apo form Phyre2 PDB 5dou chain C Region: 1 - 16 Aligned: 16 Modelled: 16 Confidence: 23.6% Identity: 25% PDB header:ligase Chain: C: PDB Molecule:carbamoyl-phosphate synthase [ammonia], mitochondrial; PDBTitle: crystal structure of human carbamoyl phosphate synthetase i (cps1),2 ligand-bound form Phyre2 PDB 4as2 chain D Region: 1 - 14 Aligned: 14 Modelled: 14 Confidence: 22.9% Identity: 50% PDB header:hydrolase Chain: D: PDB Molecule:phosphorylcholine phosphatase; PDBTitle: pseudomonas aeruginosa phosphorylcholine phosphatase. monoclinic form Phyre2 PDB 1iuk chain A Region: 1 - 16 Aligned: 16 Modelled: 16 Confidence: 22.2% Identity: 31% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 5axw chain A Region: 6 - 44 Aligned: 39 Modelled: 39 Confidence: 20.9% Identity: 18% PDB header:hydrolase/rna/dna Chain: A: PDB Molecule:crispr-associated endonuclease cas9; PDBTitle: crystal structure of staphylococcus aureus cas9 in complex with sgrna2 and target dna (ttgggt pam) Phyre2 PDB 4gxt chain A Region: 1 - 14 Aligned: 14 Modelled: 14 Confidence: 19.9% Identity: 29% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:a conserved functionally unknown protein; PDBTitle: the crystal structure of a conserved functionally unknown protein from2 anaerococcus prevotii dsm 20548 Phyre2 PDB 3dee chain A Region: 79 - 139 Aligned: 57 Modelled: 61 Confidence: 17.1% Identity: 7% PDB header:transcription Chain: A: PDB Molecule:putative regulatory protein; PDBTitle: crystal structure of a putative regulatory protein involved in2 transcription (ngo1945) from neisseria gonorrhoeae fa 1090 at 2.25 a3 resolution Phyre2 PDB 4e17 chain B Region: 71 - 94 Aligned: 24 Modelled: 24 Confidence: 16.8% Identity: 25% PDB header:cell adhesion Chain: B: PDB Molecule:catenin alpha-1; PDBTitle: alpha-e-catenin is an autoinhibited molecule that co-activates2 vinculin Phyre2 1 d1hjra_ 2 c4ep5A_ 3 d2fi0a1 4 d2ozbb1 5 d1y81a1 6 c3ff4A_ 7 c2duwA_ 8 d2d59a1 9 d1a9xa3 10 c5xavB_ 11 c5t6oA_ 12 c5o9zH_ 13 c5dotA_ 14 c5douC_ 15 c4as2D_ 16 d1iuka_ 17 c5axwA_ 18 c4gxtA_ 19 c3deeA_ 20 c4e17B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45