1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	Q	S	H	K	P	P	S	I	V	V	G	I	D	G	S	K	P	A	V	Q	A	A	L	W	A	V	D	E	A	A	S	R	D	I	P	L	R	L	L	Y	A	I	E	P	D	D	P	G	Y	A	A	H	G	A	A	A	R	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																											?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	A	A	A	E	N	A	V	R	Y	A	F	T	A	V	E	A	A	D	R	P	V	K	V	E	V	E	I	T	Q	E	R	P	V	T	S	L	I	R	A	S	A	A	A	A	L	V	C	V	G	A	I	G	V	H	H	F	R	P	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	V	G	S	T	A	A	A	L	A	L	S	A	Q	C	P	V	A	I	V	R	P	H	R	V	P	I	G	R	D	A	A	W	I	V	V	E	A	D	G	S	S	D	I	G	V	L	L	G	A	V	M	A	E	A	R	L	R	D	S
Secondary structure
SS confidence
Disorder																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		P	V	R	V	V	T	C	R	Q	S	G	V	G	D	T	G	D	D	V	R	A	S	L	D	R	W	L	A	R	W	Q	P	R	Y	P	D	V	R	V	Q	S	A	A	V	H	G	E	L	L	D	Y	L	A	G	L	G	R	S	V	H
Secondary structure
SS confidence
Disorder														?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.
Sequence		M	V	V	L	S	A	S	D	Q	E	H	V	E	Q	L	V	G	A	P	G	N	A	V	L	Q	E	A	G	C	T	L	L	V	V	G	Q	Q	Y	L
Secondary structure
SS confidence
Disorder													?																							?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 9%) Alpha helix ( 40%) Beta strand ( 21%)

Rank Aligned region

PDB 3loq chain A Region: 5 - 277 Aligned: 264 Modelled: 273 Confidence: 100.0% Identity: 15% PDB header:structure genomics, unknown function Chain: A: PDB Molecule:universal stress protein; PDBTitle: the crystal structure of a universal stress protein from archaeoglobus2 fulgidus dsm 4304 Phyre2 PDB 2jax chain A Region: 10 - 276 Aligned: 249 Modelled: 267 Confidence: 100.0% Identity: 28% PDB header:protein binding Chain: A: PDB Molecule:hypothetical protein tb31.7; PDBTitle: universal stress protein rv2623 from mycobaterium2 tuberculosis Phyre2 PDB 3ab8 chain B Region: 7 - 275 Aligned: 255 Modelled: 265 Confidence: 100.0% Identity: 22% PDB header:unknown function Chain: B: PDB Molecule:putative uncharacterized protein ttha0350; PDBTitle: crystal structure of the hypothetical tandem-type universal stress2 protein ttha0350 complexed with atps. Phyre2 PDB 3mt0 chain A Region: 2 - 277 Aligned: 259 Modelled: 258 Confidence: 100.0% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pa1789; PDBTitle: the crystal structure of a functionally unknown protein pa1789 from2 pseudomonas aeruginosa pao1 Phyre2 PDB 3olq chain A Region: 5 - 277 Aligned: 270 Modelled: 273 Confidence: 100.0% Identity: 13% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:universal stress protein e; PDBTitle: the crystal structure of a universal stress protein e from proteus2 mirabilis hi4320 Phyre2 PDB 4r2j chain A Region: 8 - 277 Aligned: 264 Modelled: 270 Confidence: 100.0% Identity: 13% PDB header:metal binding protein, unknown function Chain: A: PDB Molecule:universal stress protein e; PDBTitle: crystal structure of ydaa (universal stress protein e) from salmonella2 typhimurium Phyre2 PDB 3s3t chain D Region: 4 - 275 Aligned: 141 Modelled: 141 Confidence: 99.9% Identity: 35% PDB header:chaperone Chain: D: PDB Molecule:nucleotide-binding protein, universal stress protein uspa PDBTitle: universal stress protein uspa from lactobacillus plantarum Phyre2 PDB 3dlo chain C Region: 151 - 275 Aligned: 125 Modelled: 123 Confidence: 99.8% Identity: 19% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:universal stress protein; PDBTitle: structure of universal stress protein from archaeoglobus fulgidus Phyre2 PDB 5ahw chain C Region: 150 - 276 Aligned: 127 Modelled: 127 Confidence: 99.8% Identity: 17% PDB header:signaling protein Chain: C: PDB Molecule:universal stress protein; PDBTitle: crystal structure of universal stress protein msmeg_3811 in2 complex with camp Phyre2 PDB 2z3v chain A domain 1 Region: 151 - 274 Aligned: 124 Modelled: 124 Confidence: 99.8% Identity: 16% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: Universal stress protein-like Phyre2 PDB 1mjh chain A Region: 151 - 278 Aligned: 128 Modelled: 128 Confidence: 99.8% Identity: 14% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: Universal stress protein-like Phyre2 PDB 3hgm chain D Region: 151 - 274 Aligned: 124 Modelled: 124 Confidence: 99.8% Identity: 19% PDB header:signaling protein Chain: D: PDB Molecule:universal stress protein tead; PDBTitle: universal stress protein tead from the trap transporter teaabc of2 halomonas elongata Phyre2 PDB 1tq8 chain A Region: 149 - 276 Aligned: 121 Modelled: 128 Confidence: 99.8% Identity: 15% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: Universal stress protein-like Phyre2 PDB 3fh0 chain A Region: 150 - 275 Aligned: 123 Modelled: 126 Confidence: 99.8% Identity: 25% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative universal stress protein kpn_01444; PDBTitle: crystal structure of putative universal stress protein kpn_01444 -2 atpase Phyre2 PDB 3fg9 chain B Region: 147 - 275 Aligned: 129 Modelled: 129 Confidence: 99.7% Identity: 15% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein of universal stress protein uspa family; PDBTitle: the crystal structure of an universal stress protein uspa2 family protein from lactobacillus plantarum wcfs1 Phyre2 PDB 4r2l chain B Region: 152 - 275 Aligned: 124 Modelled: 124 Confidence: 99.7% Identity: 27% PDB header:unknown function Chain: B: PDB Molecule:universal stress protein f; PDBTitle: crystal structure of ynaf (universal stress protein f) from salmonella2 typhimurium Phyre2 PDB 4wny chain A Region: 151 - 276 Aligned: 116 Modelled: 126 Confidence: 99.7% Identity: 22% PDB header:signaling protein Chain: A: PDB Molecule:universal stress protein; PDBTitle: crystal structure of a protein from the universal stress protein2 family from burkholderia pseudomallei Phyre2 PDB 1jmv chain A Region: 151 - 277 Aligned: 125 Modelled: 127 Confidence: 99.7% Identity: 16% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: Universal stress protein-like Phyre2 PDB 2gm3 chain A domain 1 Region: 151 - 278 Aligned: 121 Modelled: 128 Confidence: 99.7% Identity: 12% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: Universal stress protein-like Phyre2 PDB 2pfs chain A Region: 151 - 275 Aligned: 115 Modelled: 125 Confidence: 99.7% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:universal stress protein; PDBTitle: crystal structure of universal stress protein from nitrosomonas2 europaea Phyre2 1 c3loqA_ 2 c2jaxA_ 3 c3ab8B_ 4 c3mt0A_ 5 c3olqA_ 6 c4r2jA_ 7 c3s3tD_ 8 c3dloC_ 9 c5ahwC_ 10 d2z3va1 11 d1mjha_ 12 c3hgmD_ 13 d1tq8a_ 14 c3fh0A_ 15 c3fg9B_ 16 c4r2lB_ 17 c4wnyA_ 18 d1jmva_ 19 d2gm3a1 20 c2pfsA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108