1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	T	T	L	P	V	Q	R	H	P	R	S	L	F	P	E	F	S	E	L	F	A	A	F	P	S	F	A	G	L	R	P	T	F	D	T	R	L	M	R	L	E	D	E	M	K	E	G	R	Y	E	V	R	A	E	L	P	G	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?		?	?	?	?													?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	P	D	K	D	V	D	I	M	V	R	D	G	Q	L	T	I	K	A	E	R	T	E	Q	K	D	F	D	G	R	S	E	F	A	Y	G	S	F	V	R	T	V	S	L	P	V	G	A	D	E	D	D	I	K	A	T	Y	D	K	G
Secondary structure
SS confidence
Disorder																								?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.
Sequence		I	L	T	V	S	V	A	V	S	E	G	K	P	T	E	K	H	I	Q	I	R	S	T	N
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?	?	?	?						?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 30%) Alpha helix ( 12%) Beta strand ( 48%)

Rank Aligned region

PDB 5mb8 chain J Region: 1 - 141 Aligned: 139 Modelled: 141 Confidence: 100.0% Identity: 22% PDB header:chaperone Chain: J: PDB Molecule:25.3 kda heat shock protein, chloroplastic; PDBTitle: hsp21 dodecamer, structural model based on cryo-em and homology2 modelling Phyre2 PDB 1gme chain A Region: 2 - 142 Aligned: 138 Modelled: 141 Confidence: 100.0% Identity: 30% Fold: HSP20-like chaperones Superfamily: HSP20-like chaperones Family: HSP20 Phyre2 PDB 3w1z chain A Region: 18 - 141 Aligned: 123 Modelled: 124 Confidence: 99.9% Identity: 33% PDB header:chaperone Chain: A: PDB Molecule:heat shock protein 16; PDBTitle: heat shock protein 16.0 from schizosaccharomyces pombe Phyre2 PDB 2ygd chain V Region: 1 - 141 Aligned: 137 Modelled: 141 Confidence: 99.9% Identity: 23% PDB header:chaperone Chain: V: PDB Molecule: PDBTitle: molecular architectures of the 24meric eye lens chaperone alphab-2 crystallin elucidated by a triple hybrid approach Phyre2 PDB 3w1z chain D Region: 38 - 141 Aligned: 103 Modelled: 104 Confidence: 99.9% Identity: 33% PDB header:chaperone Chain: D: PDB Molecule:heat shock protein 16; PDBTitle: heat shock protein 16.0 from schizosaccharomyces pombe Phyre2 PDB 6dv5 chain T Region: 1 - 141 Aligned: 136 Modelled: 140 Confidence: 99.9% Identity: 21% PDB header:chaperone Chain: T: PDB Molecule:heat shock protein beta-1; PDBTitle: oligomeric complex of a hsp27 24-mer at 3.6 a resolution Phyre2 PDB 4ydz chain A Region: 18 - 144 Aligned: 122 Modelled: 127 Confidence: 99.9% Identity: 18% PDB header:chaperone Chain: A: PDB Molecule:stress-induced protein 1; PDBTitle: stress-induced protein 1 from caenorhabditis elegans Phyre2 PDB 5mb8 chain L Region: 40 - 141 Aligned: 101 Modelled: 102 Confidence: 99.9% Identity: 26% PDB header:chaperone Chain: L: PDB Molecule:25.3 kda heat shock protein, chloroplastic; PDBTitle: hsp21 dodecamer, structural model based on cryo-em and homology2 modelling Phyre2 PDB 1gme chain B Region: 40 - 142 Aligned: 102 Modelled: 103 Confidence: 99.9% Identity: 36% Fold: HSP20-like chaperones Superfamily: HSP20-like chaperones Family: HSP20 Phyre2 PDB 2bol chain A Region: 1 - 139 Aligned: 133 Modelled: 139 Confidence: 99.9% Identity: 16% PDB header:heat shock protein Chain: A: PDB Molecule:small heat shock protein; PDBTitle: crystal structure and assembly of tsp36, a metazoan small heat shock2 protein Phyre2 PDB 1shs chain D Region: 30 - 141 Aligned: 110 Modelled: 112 Confidence: 99.9% Identity: 23% PDB header:heat shock protein Chain: D: PDB Molecule:small heat shock protein; PDBTitle: small heat shock protein from methanococcus jannaschii Phyre2 PDB 1shs chain A Region: 30 - 141 Aligned: 110 Modelled: 112 Confidence: 99.9% Identity: 23% Fold: HSP20-like chaperones Superfamily: HSP20-like chaperones Family: HSP20 Phyre2 PDB 3gla chain A Region: 38 - 129 Aligned: 91 Modelled: 92 Confidence: 99.9% Identity: 31% PDB header:chaperone Chain: A: PDB Molecule:low molecular weight heat shock protein; PDBTitle: crystal structure of the hspa from xanthomonas axonopodis Phyre2 PDB 4fei chain A Region: 35 - 132 Aligned: 96 Modelled: 98 Confidence: 99.9% Identity: 22% PDB header:chaperone Chain: A: PDB Molecule:heat shock protein-related protein; PDBTitle: hsp17.7 from deinococcus radiodurans Phyre2 PDB 3l1e chain A Region: 39 - 141 Aligned: 99 Modelled: 103 Confidence: 99.9% Identity: 20% PDB header:chaperone Chain: A: PDB Molecule:alpha-crystallin a chain; PDBTitle: bovine alphaa crystallin zinc bound Phyre2 PDB 6ewn chain A Region: 37 - 132 Aligned: 95 Modelled: 96 Confidence: 99.8% Identity: 34% PDB header:chaperone Chain: A: PDB Molecule:hspa; PDBTitle: hspa from thermosynechococcus vulcanus in the presence of 2m urea with2 initial stages of denaturation Phyre2 PDB 5ltw chain K Region: 25 - 129 Aligned: 101 Modelled: 100 Confidence: 99.8% Identity: 20% PDB header:protein binding Chain: K: PDB Molecule:heat shock protein beta-6; PDBTitle: complex of human 14-3-3 sigma clu1 mutant with phosphorylated heat2 shock protein b6 Phyre2 PDB 6f2r chain K Region: 28 - 141 Aligned: 110 Modelled: 98 Confidence: 99.8% Identity: 20% PDB header:chaperone Chain: K: PDB Molecule:hspb2,heat shock protein beta-2,heat shock protein beta-2, PDBTitle: a hetrotetramer of human hspb2 and hspb3 Phyre2 PDB 4ylc chain F Region: 11 - 127 Aligned: 106 Modelled: 117 Confidence: 99.8% Identity: 18% PDB header:chaperone Chain: F: PDB Molecule:heat shock protein hsp20; PDBTitle: crystal structure of del-c4 mutant of hsp14.1 from sulfolobus2 solfatataricus p2 Phyre2 PDB 3aab chain A Region: 39 - 136 Aligned: 97 Modelled: 98 Confidence: 99.8% Identity: 19% PDB header:chaperone Chain: A: PDB Molecule:putative uncharacterized protein st1653; PDBTitle: small heat shock protein hsp14.0 with the mutations of i120f and i122f2 in the form i crystal Phyre2 1 c5mb8J_ 2 d1gmea_ 3 c3w1zA_ 4 c2ygdV_ 5 c3w1zD_ 6 c6dv5T_ 7 c4ydzA_ 8 c5mb8L_ 9 d1gmeb_ 10 c2bolA_ 11 c1shsD_ 12 d1shsa_ 13 c3glaA_ 14 c4feiA_ 15 c3l1eA_ 16 c6ewnA_ 17 c5ltwK_ 18 c6f2rK_ 19 c4ylcF_ 20 c3aabA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99