1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	L	D	R	Y	G	T	D	V	L	A	A	G	G	R	R	R	P	R	S	V	E	H	P	V	E	L	G	M	V	V	E	D	A	E	T	G	Y	V	G	A	V	V	R	V	E	Y	G	R	I	D	L	E	D	R	Y	G	K	T	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?				?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?																															?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	F	P	L	G	P	G	Y	L	L	D	G	L	P	V	I	L	T	A	P	R	C	A	A	A	A	G	P	R	R	T	A	S	G	S	V	A	V	P	G	A	R	A	R	V	A	R	A	S	R	I	Y	V	E	G	R	H	D	A	E
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	I	A	A	V	W	G	A	D	L	R	I	E	G	V	V	V	E	H	L	G	G	V	D	D	L	V	E	I	V	A	K	F	R	P	G	P	R	R	R	L	G	V	L	V	D	H	L	V	A	G	S	K	E	A	R	I	A	E	V
Secondary structure
SS confidence
Disorder																																				?			?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	R	R	G	P	G	G	S	D	T	L	V	V	G	H	P	Y	V	D	I	W	Q	A	V	K	P	Q	R	V	G	L	A	A	W	P	R	V	P	R	H	I	E	W	K	H	G	V	C	D	A	L	G	W	P	H	A	D	Q	A	D
Secondary structure
SS confidence
Disorder				?	?	?																					?	?	?			?																										?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence		I	A	A	A	W	R	R	I	R	S	Q	V	R	D	W	T	D	L	E	P	A	L	I	G	R	V	E	E	L	I	D	F	V	T	Q	P	A	G	D	E
Secondary structure
SS confidence
Disorder																																				?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 26%) Alpha helix ( 36%) Beta strand ( 20%)

Rank Aligned region

PDB 4r36 chain A Region: 228 - 273 Aligned: 46 Modelled: 46 Confidence: 28.2% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:putative acyl-[acyl-carrier-protein]--udp-n- PDBTitle: crystal structure analysis of lpxa, a udp-n-acetylglucosamine2 acyltransferase from bacteroides fragilis 9343 Phyre2 PDB 4wxl chain B Region: 71 - 115 Aligned: 45 Modelled: 45 Confidence: 24.4% Identity: 27% PDB header:hydrolase Chain: B: PDB Molecule:peptide deformylase; PDBTitle: crystal structure of a peptide deformylase from haemophilus influenzae2 complex with actinonin Phyre2 PDB 2def chain A Region: 71 - 116 Aligned: 46 Modelled: 46 Confidence: 24.0% Identity: 22% Fold: Peptide deformylase Superfamily: Peptide deformylase Family: Peptide deformylase Phyre2 PDB 5xxe chain D Region: 230 - 248 Aligned: 19 Modelled: 19 Confidence: 23.4% Identity: 32% PDB header:dna binding protein Chain: D: PDB Molecule:protection of telomeres protein tpz1; PDBTitle: crystal structure of poz1 and tpz1 Phyre2 PDB 2jf2 chain A domain 1 Region: 228 - 273 Aligned: 46 Modelled: 46 Confidence: 23.0% Identity: 17% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: UDP N-acetylglucosamine acyltransferase Phyre2 PDB 5xxe chain C Region: 230 - 248 Aligned: 19 Modelled: 19 Confidence: 22.8% Identity: 32% PDB header:dna binding protein Chain: C: PDB Molecule:protection of telomeres protein tpz1; PDBTitle: crystal structure of poz1 and tpz1 Phyre2 PDB 4cg4 chain D Region: 63 - 85 Aligned: 23 Modelled: 23 Confidence: 21.1% Identity: 22% PDB header:actin-binding protein Chain: D: PDB Molecule:pyrin; PDBTitle: crystal structure of the chs-b30.2 domains of trim20 Phyre2 PDB 3mml chain D Region: 66 - 101 Aligned: 34 Modelled: 36 Confidence: 17.6% Identity: 32% PDB header:hydrolase Chain: D: PDB Molecule:allophanate hydrolase subunit 1; PDBTitle: allophanate hydrolase complex from mycobacterium smegmatis, msmeg0435-2 msmeg0436 Phyre2 PDB 6e1j chain B Region: 199 - 275 Aligned: 70 Modelled: 77 Confidence: 16.2% Identity: 20% PDB header:plant protein Chain: B: PDB Molecule:2-isopropylmalate synthase, a genome specific 1; PDBTitle: crystal structure of methylthioalkylmalate synthase (bjumam1.1) from2 brassica juncea Phyre2 PDB 3qu1 chain B Region: 68 - 116 Aligned: 49 Modelled: 49 Confidence: 14.0% Identity: 27% PDB header:hydrolase, metal binding protein Chain: B: PDB Molecule:peptide deformylase 2; PDBTitle: peptide deformylase from vibrio cholerae Phyre2 PDB 1xeo chain A domain 1 Region: 71 - 115 Aligned: 45 Modelled: 45 Confidence: 14.0% Identity: 22% Fold: Peptide deformylase Superfamily: Peptide deformylase Family: Peptide deformylase Phyre2 PDB 5j46 chain A Region: 71 - 115 Aligned: 45 Modelled: 45 Confidence: 14.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:peptide deformylase; PDBTitle: crystal structure of a peptide deformylase from burkholderia2 multivorans Phyre2 PDB 2kdc chain C Region: 262 - 277 Aligned: 16 Modelled: 16 Confidence: 13.7% Identity: 19% PDB header:transferase Chain: C: PDB Molecule:diacylglycerol kinase; PDBTitle: nmr solution structure of e. coli diacylglycerol kinase2 (dagk) in dpc micelles Phyre2 PDB 2epg chain B Region: 55 - 77 Aligned: 23 Modelled: 23 Confidence: 12.4% Identity: 48% PDB header:ligase Chain: B: PDB Molecule:hypothetical protein ttha1785; PDBTitle: crystal structure of ttha1785 Phyre2 PDB 5ip0 chain C Region: 249 - 274 Aligned: 23 Modelled: 23 Confidence: 11.8% Identity: 13% PDB header:structural protein Chain: C: PDB Molecule:pha granule-associated protein; PDBTitle: pha binding protein phap (phasin) Phyre2 PDB 6fln chain E Region: 63 - 80 Aligned: 18 Modelled: 18 Confidence: 11.4% Identity: 22% PDB header:protein binding Chain: E: PDB Molecule:e3 ubiquitin/isg15 ligase trim25; PDBTitle: crystal structure of the human trim25 coiled-coil and pryspry domains Phyre2 PDB 5vwx chain B Region: 175 - 184 Aligned: 10 Modelled: 10 Confidence: 11.1% Identity: 60% PDB header:apoptosis Chain: B: PDB Molecule:bcl-2-like protein 11; PDBTitle: bak core latch dimer in complex with bim-h0-h3glt Phyre2 PDB 5vwx chain D Region: 175 - 184 Aligned: 10 Modelled: 10 Confidence: 11.1% Identity: 60% PDB header:apoptosis Chain: D: PDB Molecule:bcl-2-like protein 11; PDBTitle: bak core latch dimer in complex with bim-h0-h3glt Phyre2 PDB 1e3o chain C domain 2 Region: 237 - 269 Aligned: 28 Modelled: 33 Confidence: 11.1% Identity: 29% Fold: lambda repressor-like DNA-binding domains Superfamily: lambda repressor-like DNA-binding domains Family: POU-specific domain Phyre2 PDB 2e6i chain A Region: 66 - 73 Aligned: 8 Modelled: 8 Confidence: 11.0% Identity: 38% PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase itk/tsk; PDBTitle: solution structure of the btk motif of tyrosine-protein2 kinase itk from human Phyre2 1 c4r36A_ 2 c4wxlB_ 3 d2defa_ 4 c5xxeD_ 5 d2jf2a1 6 c5xxeC_ 7 c4cg4D_ 8 c3mmlD_ 9 c6e1jB_ 10 c3qu1B_ 11 d1xeoa1 12 c5j46A_ 13 c2kdcC_ 14 c2epgB_ 15 c5ip0C_ 16 c6flnE_ 17 c5vwxB_ 18 c5vwxD_ 19 d1e3oc2 20 c2e6iA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79