1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	A	G	T	R	D	A	D	A	C	P	G	A	L	R	P	H	Q	A	A	D	G	A	L	A	R	I	R	L	P	G	G	M	I	T	A	A	Q	L	A	T	L	A	S	V	A	S	D	F	G	S	A	T	L	E	L	T	A	R	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		N	V	Q	L	R	G	I	R	D	V	A	A	V	A	D	A	V	A	K	A	G	L	L	P	S	A	T	H	E	R	V	R	N	I	V	A	S	P	L	S	G	R	A	G	G	L	A	D	V	R	A	W	V	G	E	L	D	A	A	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	A	E	P	R	L	A	E	L	G	G	R	F	W	F	G	L	D	D	G	R	A	D	V	S	G	L	G	A	D	V	G	V	Q	V	F	P	D	G	P	R	L	L	L	T	G	R	D	T	G	V	R	V	A	D	V	A	E	T	L
Secondary structure
SS confidence
Disorder								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	E	V	A	L	R	F	V	K	I	R	E	T	A	W	R	V	T	E	L	A	D	I	G	E	L	Q	S	G	V	E	L	G	P	S	V	R	P	V	T	K	T	P	V	G	W	I	P	Q	D	D	S	R	V	T	L	G	A	A	V
Secondary structure
SS confidence
Disorder																																					?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	L	G	V	L	P	A	R	V	A	E	C	L	A	A	I	E	A	P	L	V	I	T	P	W	R	S	V	L	I	C	D	L	D	D	A	T	A	D	A	A	L	R	V	L	A	P	L	G	L	V	F	D	E	N	S	P	W	L	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		I	S	A	C	T	G	S	P	G	C	A	H	S	A	A	D	V	R	A	D	A	A	R	S	L	N	V	E	S	A	G	H	R	H	F	V	G	C	E	R	A	C	G	S	P	P	A	G	E	V	L	V	A	T	G	G	G	Y	R	R
Secondary structure
SS confidence
Disorder																															?																											?	?	?	?
Disorder confidence
		.	.	.
Sequence		L	R	P
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 6%) Alpha helix ( 31%) Beta strand ( 22%)

Rank Aligned region

PDB 1zj8 chain B Region: 12 - 361 Aligned: 349 Modelled: 350 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: B: PDB Molecule:probable ferredoxin-dependent nitrite reductase nira; PDBTitle: structure of mycobacterium tuberculosis nira protein Phyre2 PDB 3b0n chain A Region: 12 - 361 Aligned: 350 Modelled: 350 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: A: PDB Molecule:nitrite reductase; PDBTitle: q448k mutant of assimilatory nitrite reductase (nii3) from tobbaco2 leaf Phyre2 PDB 2akj chain A Region: 12 - 361 Aligned: 350 Modelled: 350 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:ferredoxin--nitrite reductase, chloroplast; PDBTitle: structure of spinach nitrite reductase Phyre2 PDB 5h92 chain A Region: 18 - 361 Aligned: 344 Modelled: 344 Confidence: 100.0% Identity: 23% PDB header:oxidoreductase/electron transport Chain: A: PDB Molecule:sulfite reductase [ferredoxin], chloroplastic; PDBTitle: crystal structure of the complex between maize sulfite reductase and2 ferredoxin in the form-3 crystal Phyre2 PDB 5aop chain A Region: 24 - 361 Aligned: 329 Modelled: 334 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:sulfite reductase hemoprotein; PDBTitle: sulfite reductase structure reduced with crii edta, 5-coordinate2 siroheme, siroheme feii, [4fe-4s] +1 Phyre2 PDB 2v4j chain E Region: 11 - 220 Aligned: 209 Modelled: 209 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: E: PDB Molecule:sulfite reductase, dissimilatory-type subunit PDBTitle: the crystal structure of desulfovibrio vulgaris2 dissimilatory sulfite reductase bound to dsrc provides3 novel insights into the mechanism of sulfate respiration Phyre2 PDB 3c7b chain E Region: 11 - 220 Aligned: 208 Modelled: 209 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: E: PDB Molecule:sulfite reductase, dissimilatory-type subunit beta; PDBTitle: structure of the dissimilatory sulfite reductase from archaeoglobus2 fulgidus Phyre2 PDB 2v4j chain A Region: 23 - 213 Aligned: 191 Modelled: 190 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:sulfite reductase, dissimilatory-type subunit PDBTitle: the crystal structure of desulfovibrio vulgaris2 dissimilatory sulfite reductase bound to dsrc provides3 novel insights into the mechanism of sulfate respiration Phyre2 PDB 3c7b chain A Region: 23 - 220 Aligned: 198 Modelled: 198 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:sulfite reductase, dissimilatory-type subunit alpha; PDBTitle: structure of the dissimilatory sulfite reductase from archaeoglobus2 fulgidus Phyre2 PDB 1zj8 chain A domain 4 Region: 88 - 229 Aligned: 141 Modelled: 142 Confidence: 99.9% Identity: 17% Fold: Nitrite and sulphite reductase 4Fe-4S domain-like Superfamily: Nitrite and sulphite reductase 4Fe-4S domain-like Family: Nitrite and sulphite reductase 4Fe-4S domain-like Phyre2 PDB 2akj chain A domain 4 Region: 89 - 220 Aligned: 132 Modelled: 132 Confidence: 99.9% Identity: 17% Fold: Nitrite and sulphite reductase 4Fe-4S domain-like Superfamily: Nitrite and sulphite reductase 4Fe-4S domain-like Family: Nitrite and sulphite reductase 4Fe-4S domain-like Phyre2 PDB 1aop chain A domain 3 Region: 88 - 224 Aligned: 132 Modelled: 137 Confidence: 99.9% Identity: 13% Fold: Nitrite and sulphite reductase 4Fe-4S domain-like Superfamily: Nitrite and sulphite reductase 4Fe-4S domain-like Family: Nitrite and sulphite reductase 4Fe-4S domain-like Phyre2 PDB 3c7b chain A domain 3 Region: 90 - 220 Aligned: 131 Modelled: 131 Confidence: 99.9% Identity: 13% Fold: Nitrite and sulphite reductase 4Fe-4S domain-like Superfamily: Nitrite and sulphite reductase 4Fe-4S domain-like Family: Nitrite and sulphite reductase 4Fe-4S domain-like Phyre2 PDB 2v4j chain A domain 3 Region: 88 - 220 Aligned: 133 Modelled: 133 Confidence: 99.9% Identity: 14% Fold: Nitrite and sulphite reductase 4Fe-4S domain-like Superfamily: Nitrite and sulphite reductase 4Fe-4S domain-like Family: Nitrite and sulphite reductase 4Fe-4S domain-like Phyre2 PDB 2akj chain A domain 2 Region: 12 - 88 Aligned: 77 Modelled: 77 Confidence: 99.9% Identity: 30% Fold: Ferredoxin-like Superfamily: Nitrite/Sulfite reductase N-terminal domain-like Family: Duplicated SiR/NiR-like domains 1 and 3 Phyre2 PDB 1zj8 chain A domain 2 Region: 12 - 87 Aligned: 76 Modelled: 76 Confidence: 99.9% Identity: 30% Fold: Ferredoxin-like Superfamily: Nitrite/Sulfite reductase N-terminal domain-like Family: Duplicated SiR/NiR-like domains 1 and 3 Phyre2 PDB 2v4j chain B domain 3 Region: 88 - 220 Aligned: 133 Modelled: 133 Confidence: 99.8% Identity: 17% Fold: Nitrite and sulphite reductase 4Fe-4S domain-like Superfamily: Nitrite and sulphite reductase 4Fe-4S domain-like Family: Nitrite and sulphite reductase 4Fe-4S domain-like Phyre2 PDB 3c7b chain B domain 2 Region: 11 - 91 Aligned: 79 Modelled: 81 Confidence: 99.8% Identity: 22% Fold: Ferredoxin-like Superfamily: Nitrite/Sulfite reductase N-terminal domain-like Family: DsrA/DsrB N-terminal-domain-like Phyre2 PDB 3c7b chain B domain 3 Region: 90 - 220 Aligned: 131 Modelled: 130 Confidence: 99.8% Identity: 13% Fold: Nitrite and sulphite reductase 4Fe-4S domain-like Superfamily: Nitrite and sulphite reductase 4Fe-4S domain-like Family: Nitrite and sulphite reductase 4Fe-4S domain-like Phyre2 PDB 2v4j chain B domain 2 Region: 11 - 88 Aligned: 78 Modelled: 78 Confidence: 99.8% Identity: 15% Fold: Ferredoxin-like Superfamily: Nitrite/Sulfite reductase N-terminal domain-like Family: DsrA/DsrB N-terminal-domain-like Phyre2 1 c1zj8B_ 2 c3b0nA_ 3 c2akjA_ 4 c5h92A_ 5 c5aopA_ 6 c2v4jE_ 7 c3c7bE_ 8 c2v4jA_ 9 c3c7bA_ 10 d1zj8a4 11 d2akja4 12 d1aopa3 13 d3c7ba3 14 d2v4ja3 15 d2akja2 16 d1zj8a2 17 d2v4jb3 18 d3c7bb2 19 d3c7bb3 20 d2v4jb2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99