1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	V	V	C	L	I	G	G	V	A	G	S	L	W	P	R	P	A	G	R	L	R	G	G	C	Y	F	A	F	M	G	V	A	W	V	L	L	A	I	S	A	I	A	N	A	V	K	G	S	L	W	W	D	I	W	S	L	G	L	L
Secondary structure
SS confidence
Disorder		?	?			?	?	?				?					?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.
Sequence		V	L	I	P	A	V	V	Y	G	K	M	R	R	S	R	R	I	S	S	D	Q	D	R
Secondary structure
SS confidence
Disorder													?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 24%) Alpha helix ( 65%) Beta strand ( 11%) TM helix ( 34%) (View membrane topology prediction)

Rank Aligned region

PDB 6n3q chain D Region: 54 - 81 Aligned: 28 Modelled: 28 Confidence: 47.3% Identity: 14% PDB header:transport protein Chain: D: PDB Molecule:protein translocation protein sec63; PDBTitle: cryo-em structure of the yeast sec complex Phyre2 PDB 6nd1 chain A Region: 27 - 81 Aligned: 53 Modelled: 55 Confidence: 42.1% Identity: 17% PDB header:protein transport Chain: A: PDB Molecule:protein translocation protein sec63; PDBTitle: cryoem structure of the sec complex from yeast Phyre2 PDB 2dfx chain I Region: 6 - 25 Aligned: 20 Modelled: 20 Confidence: 33.1% Identity: 30% PDB header:hydrolase Chain: I: PDB Molecule:colicin-e5 immunity protein; PDBTitle: crystal structure of the carboxy terminal domain of colicin2 e5 complexed with its inhibitor Phyre2 PDB 6g67 chain A Region: 28 - 48 Aligned: 18 Modelled: 18 Confidence: 17.2% Identity: 56% PDB header:de novo protein Chain: A: PDB Molecule:cc-type2-ii; PDBTitle: crystal structure of a parallel eight-helix coiled coil cc-type2-ii Phyre2 PDB 6g67 chain B Region: 28 - 48 Aligned: 18 Modelled: 18 Confidence: 17.2% Identity: 56% PDB header:de novo protein Chain: B: PDB Molecule:cc-type2-ii; PDBTitle: crystal structure of a parallel eight-helix coiled coil cc-type2-ii Phyre2 PDB 3gek chain A Region: 15 - 41 Aligned: 27 Modelled: 27 Confidence: 14.4% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative thioesterase yhda; PDBTitle: crystal structure of putative thioesterase yhda from lactococcus2 lactis. northeast structural genomics consortium target kr113 Phyre2 PDB 6g66 chain C Region: 28 - 48 Aligned: 18 Modelled: 18 Confidence: 13.4% Identity: 56% PDB header:de novo protein Chain: C: PDB Molecule:cc-type2-iv; PDBTitle: crystal structure of a parallel seven-helix coiled coil cc-type2-iv Phyre2 PDB 6g66 chain D Region: 28 - 48 Aligned: 18 Modelled: 18 Confidence: 13.4% Identity: 56% PDB header:de novo protein Chain: D: PDB Molecule:cc-type2-iv; PDBTitle: crystal structure of a parallel seven-helix coiled coil cc-type2-iv Phyre2 PDB 6g66 chain E Region: 28 - 48 Aligned: 18 Modelled: 18 Confidence: 13.4% Identity: 56% PDB header:de novo protein Chain: E: PDB Molecule:cc-type2-iv; PDBTitle: crystal structure of a parallel seven-helix coiled coil cc-type2-iv Phyre2 PDB 6g66 chain B Region: 28 - 48 Aligned: 18 Modelled: 18 Confidence: 13.4% Identity: 56% PDB header:de novo protein Chain: B: PDB Molecule:cc-type2-iv; PDBTitle: crystal structure of a parallel seven-helix coiled coil cc-type2-iv Phyre2 PDB 6g66 chain G Region: 28 - 48 Aligned: 18 Modelled: 18 Confidence: 13.4% Identity: 56% PDB header:de novo protein Chain: G: PDB Molecule:cc-type2-iv; PDBTitle: crystal structure of a parallel seven-helix coiled coil cc-type2-iv Phyre2 PDB 6g66 chain A Region: 28 - 48 Aligned: 18 Modelled: 18 Confidence: 13.4% Identity: 56% PDB header:de novo protein Chain: A: PDB Molecule:cc-type2-iv; PDBTitle: crystal structure of a parallel seven-helix coiled coil cc-type2-iv Phyre2 PDB 6g66 chain F Region: 28 - 48 Aligned: 18 Modelled: 18 Confidence: 13.4% Identity: 56% PDB header:de novo protein Chain: F: PDB Molecule:cc-type2-iv; PDBTitle: crystal structure of a parallel seven-helix coiled coil cc-type2-iv Phyre2 PDB 2f0x chain A domain 1 Region: 14 - 40 Aligned: 27 Modelled: 27 Confidence: 12.8% Identity: 15% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 1zmm chain A Region: 4 - 9 Aligned: 6 Modelled: 6 Confidence: 11.6% Identity: 100% PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 4; PDBTitle: crystal structure of human alpha-defensin-4 Phyre2 PDB 1zmm chain C Region: 4 - 9 Aligned: 6 Modelled: 6 Confidence: 11.6% Identity: 100% PDB header:antimicrobial protein Chain: C: PDB Molecule:neutrophil defensin 4; PDBTitle: crystal structure of human alpha-defensin-4 Phyre2 PDB 6dmq chain E Region: 4 - 9 Aligned: 6 Modelled: 6 Confidence: 11.5% Identity: 100% PDB header:antimicrobial protein Chain: E: PDB Molecule:neutrophil defensin 4; PDBTitle: crystal structure of the t27a mutant of human alpha defensin hnp4. Phyre2 PDB 6dmq chain H Region: 4 - 9 Aligned: 6 Modelled: 6 Confidence: 11.5% Identity: 100% PDB header:antimicrobial protein Chain: H: PDB Molecule:neutrophil defensin 4; PDBTitle: crystal structure of the t27a mutant of human alpha defensin hnp4. Phyre2 PDB 6dmq chain C Region: 4 - 9 Aligned: 6 Modelled: 6 Confidence: 11.5% Identity: 100% PDB header:antimicrobial protein Chain: C: PDB Molecule:neutrophil defensin 4; PDBTitle: crystal structure of the t27a mutant of human alpha defensin hnp4. Phyre2 PDB 6dmq chain G Region: 4 - 9 Aligned: 6 Modelled: 6 Confidence: 11.5% Identity: 100% PDB header:antimicrobial protein Chain: G: PDB Molecule:neutrophil defensin 4; PDBTitle: crystal structure of the t27a mutant of human alpha defensin hnp4. Phyre2 1 c6n3qD_ 2 c6nd1A_ 3 c2dfxI_ 4 c6g67A_ 5 c6g67B_ 6 c3gekA_ 7 c6g66C_ 8 c6g66D_ 9 c6g66E_ 10 c6g66B_ 11 c6g66G_ 12 c6g66A_ 13 c6g66F_ 14 d2f0xa1 15 c1zmmA_ 16 c1zmmC_ 17 c6dmqE_ 18 c6dmqH_ 19 c6dmqC_ 20 c6dmqG_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55