1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	A	T	L	S	Q	I	R	A	W	S	T	E	H	L	I	D	A	A	G	Y	W	T	E	T	A	D	R	W	E	D	V	F	L	Q	M	R	N	Q	A	H	A	I	A	W	N	G	A	G	G	D	G	L	R	Q	R	T	R	A
Secondary structure
SS confidence
Disorder		?	?	?	?					?																														?		?	?	?	?	?	?	?		?											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	F	S	T	V	S	G	I	A	D	Q	L	R	R	A	A	T	I	A	R	N	G	A	G	T	I	D	A	A	Q	R	R	V	M	Y	A	V	E	D	A	Q	D	A	G	F	N	V	G	E	D	L	S	V	T	D	T	K	T	T	Q
Secondary structure
SS confidence
Disorder																						?	?																								?										?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	A	A	V	Q	A	A	R	L	A	Q	A	Q	A	L	A	G	D	I	R	L	R	V	G	Q	L	V	A	A	E	N	E	V	S	G	Q	L	A	A	T	T	G	D	V	G	N	V	R	F	A	G	A	P	V	V	A	H	S	A	V
Secondary structure
SS confidence
Disorder		?																																?	?	?									?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	L	V	D	F	F	K	Q	D	G	P	T	P	P	P	P	G	A	P	H	P	S	G	G	A	D	G	P	Y	S	D	P	I	T	S	M	M	L	P	P	A	G	T	E	A	P	V	S	D	A	T	K	R	W	V	D	N	M	V	N
Secondary structure
SS confidence
Disorder				?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	L	A	A	R	P	P	D	D	P	I	A	V	E	A	R	R	L	A	F	Q	A	L	H	R	P	C	N	S	A	E	W	T	A	A	V	A	G	F	A	G	S	S	A	G	V	V	G	T	A	L	A	I	P	A	G	P	A	D	W
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?																											?	?		?	?	?	?	?	?	?	?	?	?	?			?	?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.
Sequence		A	L	L	G	A	A	L	L	G	V	G	G	S	G	A	A	V	V	N	C	A	T	K
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?							?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 40%) Alpha helix ( 63%) Beta strand ( 2%)

Rank Aligned region

PDB 3gvm chain A Region: 12 - 97 Aligned: 86 Modelled: 86 Confidence: 98.2% Identity: 15% PDB header:viral protein Chain: A: PDB Molecule:putative uncharacterized protein sag1039; PDBTitle: structure of the homodimeric wxg-100 family protein from streptococcus2 agalactiae Phyre2 PDB 3zbh chain C Region: 12 - 97 Aligned: 86 Modelled: 86 Confidence: 98.1% Identity: 14% PDB header:unknown function Chain: C: PDB Molecule:esxa; PDBTitle: geobacillus thermodenitrificans esxa crystal form i Phyre2 PDB 4iog chain D Region: 12 - 87 Aligned: 76 Modelled: 76 Confidence: 98.1% Identity: 16% PDB header:unknown function Chain: D: PDB Molecule:secreted protein esxb; PDBTitle: the crystal structure of a secreted protein esxb (wild-type, in p212 space group) from bacillus anthracis str. sterne Phyre2 PDB 2vs0 chain B Region: 12 - 87 Aligned: 76 Modelled: 76 Confidence: 98.1% Identity: 13% PDB header:cell invasion Chain: B: PDB Molecule:virulence factor esxa; PDBTitle: structural analysis of homodimeric staphylococcal aureus2 virulence factor esxa Phyre2 PDB 2g38 chain B Region: 13 - 102 Aligned: 90 Modelled: 90 Confidence: 97.8% Identity: 12% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:ppe family protein; PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis Phyre2 PDB 2g38 chain B domain 1 Region: 13 - 102 Aligned: 90 Modelled: 90 Confidence: 97.8% Identity: 12% Fold: Ferritin-like Superfamily: PE/PPE dimer-like Family: PPE Phyre2 PDB 4lws chain A Region: 12 - 102 Aligned: 91 Modelled: 91 Confidence: 97.8% Identity: 13% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata Phyre2 PDB 1wa8 chain A domain 1 Region: 12 - 83 Aligned: 72 Modelled: 72 Confidence: 97.6% Identity: 17% Fold: Ferritin-like Superfamily: EsxAB dimer-like Family: ESAT-6 like Phyre2 PDB 4lws chain B Region: 3 - 84 Aligned: 82 Modelled: 82 Confidence: 97.5% Identity: 11% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata Phyre2 PDB 1wa8 chain B domain 1 Region: 11 - 86 Aligned: 76 Modelled: 76 Confidence: 97.5% Identity: 16% Fold: Ferritin-like Superfamily: EsxAB dimer-like Family: ESAT-6 like Phyre2 PDB 5xfs chain B Region: 13 - 103 Aligned: 91 Modelled: 91 Confidence: 97.2% Identity: 13% PDB header:protein transport Chain: B: PDB Molecule:ppe family protein ppe15; PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis Phyre2 PDB 4i0x chain J Region: 12 - 83 Aligned: 72 Modelled: 72 Confidence: 96.4% Identity: 14% PDB header:structural genomics, unknown function Chain: J: PDB Molecule:esat-6-like protein mab_3113; PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex Phyre2 PDB 2kg7 chain B Region: 10 - 84 Aligned: 75 Modelled: 75 Confidence: 95.7% Identity: 11% PDB header:unknown function Chain: B: PDB Molecule:esat-6-like protein esxh; PDBTitle: structure and features of the complex formed by the tuberculosis2 virulence factors rv0287 and rv0288 Phyre2 PDB 4i0x chain A Region: 14 - 83 Aligned: 70 Modelled: 70 Confidence: 94.9% Identity: 13% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:esat-6-like protein mab_3112; PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex Phyre2 PDB 4wj2 chain A Region: 15 - 92 Aligned: 76 Modelled: 78 Confidence: 93.9% Identity: 17% PDB header:unknown function Chain: A: PDB Molecule:antigen mtb48; PDBTitle: mycobacterial protein Phyre2 PDB 4xy3 chain A Region: 15 - 105 Aligned: 88 Modelled: 91 Confidence: 89.5% Identity: 13% PDB header:protein transport Chain: A: PDB Molecule:esx-1 secretion-associated protein espb; PDBTitle: structure of esx-1 secreted protein espb Phyre2 PDB 2eap chain A Region: 2 - 19 Aligned: 18 Modelled: 18 Confidence: 56.1% Identity: 22% PDB header:signaling protein Chain: A: PDB Molecule:lymphocyte cytosolic protein 2; PDBTitle: solution structure of the n-terminal sam-domain of human2 lymphocyte cytosolic protein 2 Phyre2 PDB 5j1h chain B Region: 4 - 72 Aligned: 63 Modelled: 69 Confidence: 19.7% Identity: 19% PDB header:structural protein Chain: B: PDB Molecule:plectin,plectin; PDBTitle: structure of the spectrin repeats 5 and 6 of the plakin domain of2 plectin Phyre2 PDB 6cg8 chain A Region: 66 - 107 Aligned: 42 Modelled: 42 Confidence: 15.8% Identity: 17% PDB header:dna binding protein/dna Chain: A: PDB Molecule:upf0335 protein b7z12_12435; PDBTitle: structure of c. crescentus gapr-dna Phyre2 PDB 2mwq chain A Region: 190 - 245 Aligned: 55 Modelled: 56 Confidence: 13.7% Identity: 24% PDB header:plant protein Chain: A: PDB Molecule:oxygen-evolving enhancer protein 3, chloroplastic; PDBTitle: solution structure of psbq from spinacia oleracea Phyre2 1 c3gvmA_ 2 c3zbhC_ 3 c4iogD_ 4 c2vs0B_ 5 c2g38B_ 6 d2g38b1 7 c4lwsA_ 8 d1wa8a1 9 c4lwsB_ 10 d1wa8b1 11 c5xfsB_ 12 c4i0xJ_ 13 c2kg7B_ 14 c4i0xA_ 15 c4wj2A_ 16 c4xy3A_ 17 c2eapA_ 18 c5j1hB_ 19 c6cg8A_ 20 c2mwqA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45